PANTHER Gene Information

Gene Symbol(s):

20205479

Organism:

helobdella robusta

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Gene Name:

Death domain-containing protein

Gene ID:

HelroG175669

Protein ID:

T1F9I0

Persistent Id:

PTN004468175

Alternate Ids:

HelroP175669(Ensembl_PRO)	XM_009023075(refSeq)
T1F9I0(Synonym)	HelroT175669(Ensembl_TRS)
HelroG175669(Ensembl)	675871526(GI)
T1F9I0_HELRO(UniProtKB-ID)	AMQM01005394(EMBL)
ESO00686(EMBL-CDS)	20205479(GeneID)
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PANTHER Classification

PANTHER Family:	MYD88 (PTHR15079)
PANTHER Subfamily:	MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 (PTHR15079:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

Toll receptor signaling pathway

myeloid differentiation factor 88

Toll pathway-drosophila

MyD88

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	Toll-like receptor binding, TIR domain binding
GO BP Complete:	Toll signaling pathway, MyD88-dependent toll-like receptor signaling pathway, innate immune response, toll-like receptor 4 signaling pathway, positive regulation of canonical NF-kappaB signal transduction, defense response to Gram-positive bacterium
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000014754.4\|UniProtKB=A0A2I3RAM8	Pan troglodytes	O
GORGO\|Gene=MYD88\|UniProtKB=B3Y680	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000995.4\|UniProtKB=H9Z267	Macaca mulatta	O
HUMAN\|HGNC=7562\|UniProtKB=Q99836	Homo sapiens	O
PANTR\|Gene=MYD88\|UniProtKB=B3Y678	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000003831.3\|UniProtKB=G3QML9	Gorilla gorilla gorilla	O
MACMU\|Gene=MYD88\|UniProtKB=B3Y683	Macaca mulatta	O
MOUSE\|MGI=MGI=108005\|UniProtKB=P22366	Mus musculus	O
RAT\|RGD=735043\|UniProtKB=Q6Y1S1	Rattus norvegicus	O
BOVIN\|Gene=MYD88\|UniProtKB=Q599T9	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000000563.6\|UniProtKB=A0A452DHW6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000011251.6\|UniProtKB=A0A140TAK4	Sus scrofa	O
PIG\|Gene=MYD88\|UniProtKB=A2TF48	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000001774.4\|UniProtKB=F6TAV5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000034951.3\|UniProtKB=A0A2I2UWG9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029799.1\|UniProtKB=A0A8I3Q209	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000001175.3\|UniProtKB=F6PH80	Ornithorhynchus anatinus	O
CHICK\|Gene_ORFName=RCJMB04_14h3\|UniProtKB=A5HNF6	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010026550.1\|UniProtKB=A0A8V1ABC8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009971.4\|UniProtKB=R4GCS1	Anolis carolinensis	O
XENLA\|Gene=myd88-b\|UniProtKB=Q5FWM2	Xenopus laevis	O
XENLA\|Gene=myd88-a\|UniProtKB=Q9DF60	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486650\|UniProtKB=Q28DJ2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009788.2\|UniProtKB=H2M1J7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040219-3\|UniProtKB=Q5XJ85	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009811.1\|UniProtKB=W5MUD1	lepisosteus oculatus	O
BRAFL\|Gene=LOC118415609\|UniProtKB=A0A9J7L4I6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403304\|UniProtKB=A0A9J7HIH8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC575153\|UniProtKB=A0A7M7PU22	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575081\|UniProtKB=A0A7M7RCP5	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0033402\|UniProtKB=Q7K105	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP005252\|UniProtKB=Q7Q9F4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003185\|UniProtKB=D6WEI3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302514\|UniProtKB=E9GDJ6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305569\|UniProtKB=E9FWB5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW008802\|UniProtKB=B7Q0A8	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g82163\|UniProtKB=A7RHZ4	Nematostella vectensis	O