PANTHER Gene Information

Gene Symbol(s):

ADCY2

Organism:

Equus caballus

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Gene Name:

Adenylate cyclase type 2

Gene ID:

ENSECAG00000016266.3

Protein ID:

A0A9L0S6J9

Persistent Id:

PTN001376393

Alternate Ids:

ENSECAT00000114515(Ensembl_TRS)	ENSECAG00000016266(Ensembl)
ENSECAP00000070471(Ensembl_PRO)	A0A9L0S6J9(Synonym)
A0A9L0S6J9_HORSE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	ADENYLATE CYCLASE TYPE 1 (PTHR45627)
PANTHER Subfamily:	ADENYLATE CYCLASE TYPE 2 (PTHR45627:SF6)
PANTHER GO-slim Molecular Function:	adenylate cyclase activity
PANTHER GO-slim Biological Process:	purine ribonucleotide biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cyclic nucleotide metabolic process
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	adenylate cyclase

Pathway Categories:

Nicotine pharmacodynamics pathway

Adenylate cyclase 2

Opioid proopiomelanocortin pathway

adenylate cyclase

Opioid prodynorphin pathway

adenylate cyclase

5HT4 type receptor mediated signaling pathway

adenylate cyclase

Inflammation mediated by chemokine and cytokine signaling pathway

adenylate cyclase

Histamine H2 receptor mediated signaling pathway

adenylate cyclase

GABA-B receptor II signaling

adenylate cyclase

Enkephalin release

adenylate cyclase

Beta1 adrenergic receptor signaling pathway

adenylate cyclase

Opioid proenkephalin pathway

adenylate cyclase

5HT1 type receptor mediated signaling pathway

adenylate cyclase

Endothelin signaling pathway

Adenylate cyclase

Beta2 adrenergic receptor signaling pathway

adenylate cyclase

Dopamine receptor mediated signaling pathway

adenylate cyclase

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Adenylyl cyclase

Beta3 adrenergic receptor signaling pathway

adenylate cyclase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, metal ion binding, lyase activity, adenylate cyclase activity
GO BP Complete:	cAMP biosynthetic process, adenylate cyclase-activating G protein-coupled receptor signaling pathway, intracellular signal transduction
GO CC Complete:	cytoplasm, membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=233\|UniProtKB=Q08462	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000049665.1\|UniProtKB=A0A2I3T3G3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011188.3\|UniProtKB=G3R6G7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018742.4\|UniProtKB=A0A1D5RHE7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=99676\|UniProtKB=Q80TL1	Mus musculus	LDO
RAT\|RGD=619965\|UniProtKB=P26769	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000019210.5\|UniProtKB=F1MJV4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017101.5\|UniProtKB=F1S0T0	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000015101.6\|UniProtKB=A0A5F5XNF6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023075.1\|UniProtKB=A0A8I3PRI5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002081.4\|UniProtKB=F6V001	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011580.4\|UniProtKB=F6ZAV4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010000808.1\|UniProtKB=E1BX91	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010038.4\|UniProtKB=G1KJT7	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000009028.2\|UniProtKB=H2LYV3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000014400.2\|UniProtKB=H2MHE4	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030004.1\|UniProtKB=A0A3B3IL43	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060503-69\|UniProtKB=F1Q5J6	Danio rerio	O
DANRE\|Gene=adcy2a\|UniProtKB=A0A8N7TBA8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000000614.1\|UniProtKB=W5LX23	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118417332\|UniProtKB=A0A9J7L9Q4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC575180\|UniProtKB=A0A7M7N5L5	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000069\|UniProtKB=O16880	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09276\|UniProtKB=A8X9H0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00103547\|UniProtKB=A0A2A6CRK1	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0004852\|UniProtKB=Q9VW60	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010436\|UniProtKB=A0A1S4H4Y3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC032331\|UniProtKB=A0A139WLU2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_65332\|UniProtKB=E9HRC9	Daphnia pulex	O
TRIAD\|EnsemblGenome=TriadG52497\|UniProtKB=B3RIR3	Trichoplax adhaerens	O
BATDJ\|Gene_ORFName=BATDEDRAFT_23648\|UniProtKB=F4NXY1	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0281545\|UniProtKB=Q03100	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51614\|UniProtKB=F1A4L3	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_16599\|UniProtKB=A8B947	Giardia intestinalis	O
PARTE\|EnsemblGenome=GSPATT00035944001\|UniProtKB=A0C7P7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028571001\|UniProtKB=A0BG69	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020771001\|UniProtKB=A0DVQ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017090001\|UniProtKB=A0DI52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008342001\|UniProtKB=A0CM46	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035991001\|UniProtKB=A0C7U3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035327001\|UniProtKB=A0C5Y1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000356001\|UniProtKB=A0BBK4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037686001\|UniProtKB=A0CEN0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037840001\|UniProtKB=A0CF34	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028233001\|UniProtKB=A0BF81	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022215001\|UniProtKB=A0E179	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008067001\|UniProtKB=A0CL53	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013081001\|UniProtKB=A0D3H6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030444001\|UniProtKB=A0BMP1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008009001\|UniProtKB=A0CKZ5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035245001\|UniProtKB=A0C5P9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036203001\|UniProtKB=A0C8F3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019986001\|UniProtKB=A0DTD8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017694001\|UniProtKB=A0DJY3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021918001\|UniProtKB=A0E0D3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000775001\|UniProtKB=A0CJU6	Paramecium tetraurelia	O
PARTE\|Gene_ORFName=PTMB.171c\|UniProtKB=Q6BG52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025644001\|UniProtKB=A0EC90	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005251001\|UniProtKB=A0BPN4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032566001\|UniProtKB=A0BVZ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030881001\|UniProtKB=A0BNX5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025082001\|UniProtKB=A0EAN1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029118001\|UniProtKB=A0BHR5	Paramecium tetraurelia	O