PANTHER Gene Information

Gene Symbol(s):

HNRNPAB

Organism:

Homo sapiens

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Gene Name:

Heterogeneous nuclear ribonucleoprotein A_B

Gene ID:

HGNC:5034

Protein ID:

Q99729

Enhancers:

View enhancers for HUMAN|HGNC=5034|UniProtKB=Q99729

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002545042

Alternate Ids:

3182(GeneID)	EAW53844(EMBL-CDS)
602688(MIM)	HGNC:5034(HGNC)
HNRNPAB(Symbol)	ABBP1(Synonym)
ROAA_HUMAN(UniProtKB-ID)	AK054600(EMBL)
33112434(GI)	D3DWP7(AltAccession)
ENSG00000197451(Ensembl)
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PANTHER Classification

PANTHER Family:	RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN (PTHR48033)
PANTHER Subfamily:	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B (PTHR48033:SF1)
PANTHER GO-slim Molecular Function:	RNA binding
PANTHER GO-slim Biological Process:	regulation of gene expression
PANTHER GO-slim Cellular Component:	chromatin nucleoplasm
PANTHER protein class:	RNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA binding, protein binding, mRNA binding
GO BP Complete:	positive regulation of DNA-templated transcription, regulation of gene expression, epithelial to mesenchymal transition, negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, mRNA modification
GO CC Complete:	nucleus, mRNA editing complex, RNA polymerase II transcription regulator complex, cytoplasm, ribonucleoprotein complex, chromatin, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000017601.6\|UniProtKB=K7CPF8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011692.3\|UniProtKB=G3R7R0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003996.4\|UniProtKB=H9YVR7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1330294\|UniProtKB=Q99020	Mus musculus	LDO
RAT\|RGD=69255\|UniProtKB=Q9QX81	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013627.6\|UniProtKB=A0A3Q1LZD9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000001932.4\|UniProtKB=F1SHL4	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000014031.5\|UniProtKB=A0A287BMB6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018242.4\|UniProtKB=A0A9L0SWC0	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845009974.1\|UniProtKB=A0A8I3NPT9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004217.4\|UniProtKB=A0A5F8G9E0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004998.4\|UniProtKB=F7GB01	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015142.1\|UniProtKB=A0A8V0YRG0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016946.4\|UniProtKB=G1KTC4	Anolis carolinensis	LDO
XENLA\|Gene=hnrnpab.L\|UniProtKB=Q7ZYE9	Xenopus laevis	O
XENLA\|Gene=hnrnpab.S\|UniProtKB=Q6GM69	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6042555\|UniProtKB=Q28BP1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005327.2\|UniProtKB=H2LL08	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-185\|UniProtKB=Q6NYU8	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2516\|UniProtKB=Q6NYA1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009773.1\|UniProtKB=W5MU82	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000016737.2\|UniProtKB=F6QZW1	Ciona intestinalis	LDO
CIOIN\|Ensembl=ENSCING00000003877.3\|UniProtKB=F6XGK4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118411250\|UniProtKB=A0A9J7KTF9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592285\|UniProtKB=A0A7M7HFN5	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0263396\|UniProtKB=Q08473	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP006668\|UniProtKB=A0NEX1	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP000399\|UniProtKB=F5HJK0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000928\|UniProtKB=D6W948	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_189289\|UniProtKB=E9HDK2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW007146\|UniProtKB=B7PVI7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG72414\|UniProtKB=T1G0Z7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG77494\|UniProtKB=T1G2Y6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG94668\|UniProtKB=T1G921	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g86628\|UniProtKB=A7RM72	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245351\|UniProtKB=A7SHQ6	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_30329\|UniProtKB=A9VDN2	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000199454\|UniProtKB=A0A1D8PIP0	Candida albicans	LDO
PUCGT\|EnsemblGenome=PGTG_20403\|UniProtKB=E3NXZ8	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_07133\|UniProtKB=E3K9E2	Puccinia graminis	LDO
ENTH1\|EnsemblGenome=EHI_183100\|UniProtKB=C4LV83	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0279695\|UniProtKB=Q54WE9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_30303\|UniProtKB=F0ZF84	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_23_0730\|UniProtKB=Q4QB90	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_24_1570\|UniProtKB=Q4QAH4	Leishmania major	LDO
TRIV3\|Gene_ORFName=TVAG_108440\|UniProtKB=A2EQG8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_345400\|UniProtKB=A2EW18	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0916700\|UniProtKB=Q8I2Y5	Plasmodium falciparum	LDO
PLAF7\|EnsemblGenome=PF3D7_0414500\|UniProtKB=Q8I1U3	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00022603001\|UniProtKB=A0E2B4	Paramecium tetraurelia	LDO
CHLRE\|EnsemblGenome=CHLRE_07g330300v5\|UniProtKB=A0A2K3DJU4	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00061p00188860\|UniProtKB=U5DCR3	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_108G00110\|UniProtKB=A0A0K9Q3V6	Zostera marina	O
MUSAM\|EnsemblGenome=Ma01_g00160\|UniProtKB=A0A804HNM1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma08_g26140\|UniProtKB=A0A804KAW6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g04530\|UniProtKB=A0A804HNA8	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma01_g12510\|UniProtKB=A0A804HTB1	Musa acuminata subsp. malaccensis	O
SORBI\|EnsemblGenome=SORBI_3007G221300\|UniProtKB=A0A1Z5RB72	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb432880\|UniProtKB=A0A1D6JH19	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb199330\|UniProtKB=B4FMA8	Zea mays	O
ORYSJ\|EnsemblGenome=Os08g0492100\|UniProtKB=B7EPZ7	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g39090v3\|UniProtKB=I1I860	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0691010\|UniProtKB=F2DUV8	Hordeum vulgare subsp. vulgare	O
SETIT\|EnsemblGenome=SETIT_014007mg\|UniProtKB=K3YID8	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G220800\|UniProtKB=C5XR18	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb028170\|UniProtKB=A0A1D6KD20	Zea mays	O
ORYSJ\|EnsemblGenome=Os08g0320100\|UniProtKB=Q6Z0P6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g20700v3\|UniProtKB=I1I2U5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0612070\|UniProtKB=A0A8I6Y5B4	Hordeum vulgare subsp. vulgare	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0473901\|UniProtKB=A0A251T9C0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0113441\|UniProtKB=A0A251V9T3	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C700380730\|UniProtKB=A0A9R1UWH2	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C900497620\|UniProtKB=A0A9R1UCI3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a019468mg\|UniProtKB=A0A022PXN9	Erythranthe guttata	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028820\|UniProtKB=M1CT90	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG401017409\|UniProtKB=M1BGT3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc12g035313.1\|UniProtKB=A0A3Q7J806	Solanum lycopersicum	O
SOLLC\|EnsemblGenome=Solyc12g035280.1\|UniProtKB=K4DDZ4	Solanum lycopersicum	O
TOBAC\|Gene=LOC107765935\|UniProtKB=A0A1S3XJM8	Nicotiana tabacum	O
TOBAC\|Gene=GTBP1\|UniProtKB=E2F3S8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107808160\|UniProtKB=A0A1S4BH10	Nicotiana tabacum	O
TOBAC\|Gene=GTBP2\|UniProtKB=E2F3S9	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi18g01859\|UniProtKB=F6GYT6	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi19g00722\|UniProtKB=A5APB9	Vitis vinifera	O
BRACM\|EnsemblGenome=Bra039380\|UniProtKB=M4FE59	Brassica campestris	O
ARATH\|TAIR=locus=504955752\|UniProtKB=Q9LHL2	Arabidopsis thaliana	O
THECC\|EnsemblGenome=TCM_030592\|UniProtKB=A0A061FBT9	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g018875mg\|UniProtKB=A0A067EVW0	Citrus sinensis	O
RICCO\|Gene_ORFName=RCOM_0523280\|UniProtKB=B9S9X4	Ricinus communis	O
CUCSA\|EnsemblGenome=Csa_7G278740\|UniProtKB=A0A0A0K3W8	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G026600\|UniProtKB=A0A251NKX9	Prunus persica	O
VITVI\|EnsemblGenome=Vitvi12g00750\|UniProtKB=D7TD96	Vitis vinifera	O
GOSHI\|Gene=LOC107950061\|UniProtKB=A0A1U8NMS6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107934006\|UniProtKB=A0A1U8M8G7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107916320\|UniProtKB=A0A1U8KK01	Gossypium hirsutum	O
GOSHI\|Gene=LOC107954751\|UniProtKB=A0A1U8P3V5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107954030\|UniProtKB=A0A1U8P179	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_002445\|UniProtKB=A0A061DU90	Theobroma cacao	O
SOYBN\|EnsemblGenome=GLYMA_13G009800\|UniProtKB=I1LXP8	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g082650\|UniProtKB=G7J8U4	Medicago truncatula	O
PRUPE\|EnsemblGenome=PRUPE_3G195500\|UniProtKB=M5XCJ4	Prunus persica	O
AMBTC\|EnsemblGenome=AMTR_s00049p00200350\|UniProtKB=W1PUU2	Amborella trichopoda	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008302mg\|UniProtKB=A0A022R542	Erythranthe guttata	O
TOBAC\|Gene=LOC107824717\|UniProtKB=A0A1S4D0S3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107799939\|UniProtKB=A0A1S4APY9	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g01694\|UniProtKB=F6HUU8	Vitis vinifera	O
BRANA\|Gene_ORFName=DARMORV10_C04P47330.1\|UniProtKB=A0A078HEZ2	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A04P13550.1\|UniProtKB=A0A078HXL9	Brassica napus	O
BRACM\|EnsemblGenome=Bra025568\|UniProtKB=M4E9W2	Brassica campestris	O
GOSHI\|Gene=LOC107892127\|UniProtKB=A0A1U8IA10	Gossypium hirsutum	O
GOSHI\|Gene=LOC107892251\|UniProtKB=A0A1U8IAH1	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_016971\|UniProtKB=A0A061EDK8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g016617mg\|UniProtKB=A0A067EML5	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_001G344900v3\|UniProtKB=B9GI65	Populus trichocarpa	O
SOYBN\|EnsemblGenome=GLYMA_19G061100\|UniProtKB=I1N727	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_16G070900\|UniProtKB=I1MLU4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g004810\|UniProtKB=A0A072U4W5	Medicago truncatula	O
CUCSA\|EnsemblGenome=Csa_3G839850\|UniProtKB=A0A0A0LG75	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G292100\|UniProtKB=M5XCB9	Prunus persica	O
AMBTC\|EnsemblGenome=AMTR_s00036p00067000\|UniProtKB=U5CQ50	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_14G01000\|UniProtKB=A0A0K9PWH1	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_339G00100\|UniProtKB=A0A0K9P828	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g13370\|UniProtKB=A0A804JVE4	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma10_g21190\|UniProtKB=A0A804KYM7	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_020253mg\|UniProtKB=K3Z135	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G095300\|UniProtKB=C5XYF2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb205130\|UniProtKB=B4FHJ8	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb240020\|UniProtKB=C0P8S9	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0221500\|UniProtKB=Q6YVH3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g08380v3\|UniProtKB=I1HYU9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0580320\|UniProtKB=F2D3D5	Hordeum vulgare subsp. vulgare	LDO
SETIT\|EnsemblGenome=SETIT_006870mg\|UniProtKB=K3XY62	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G171100\|UniProtKB=C5Z4R7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb383950\|UniProtKB=K7VDH6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb277380\|UniProtKB=B7ZX91	Zea mays	O
ORYSJ\|EnsemblGenome=Os06g0566100\|UniProtKB=A0A0P0WY24	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g37692v3\|UniProtKB=I1GXW9	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0717200\|UniProtKB=A0A8I6YGZ0	Hordeum vulgare subsp. vulgare	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0417021\|UniProtKB=A0A251U0M4	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600310970\|UniProtKB=A0A9R1X4J0	Lactuca sativa	LDO
TOBAC\|Gene=LOC107829667\|UniProtKB=A0A1S4DH69	Nicotiana tabacum	O
TOBAC\|Gene=LOC107806609\|UniProtKB=A0A1S4BBL3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107785518\|UniProtKB=A0A1S3ZD04	Nicotiana tabacum	O
TOBAC\|Gene=LOC107825670\|UniProtKB=A0A1S4D3X4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi09g00196\|UniProtKB=D7U018	Vitis vinifera	LDO
ARATH\|TAIR=locus=4515103541\|UniProtKB=F4KCG5	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2007903\|UniProtKB=F4I906	Arabidopsis thaliana	LDO
POPTR\|EnsemblGenome=POPTR_005G105700v3\|UniProtKB=U5GH90	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G196500v3\|UniProtKB=A0A2K2C0F2	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_0655610\|UniProtKB=B9S5X3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G348800\|UniProtKB=I1M5B0	Glycine max	LDO
CUCSA\|EnsemblGenome=Csa_7G450760\|UniProtKB=A0A0A0K9M1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G048000\|UniProtKB=A0A251PVC7	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_48637\|UniProtKB=D8RC63	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c26_4470\|UniProtKB=A0A2K1IBU7	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c4_17570\|UniProtKB=A0A2K1KNW2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c4_17440\|UniProtKB=A0A2K1KNV9	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0002s0093\|UniProtKB=A0A2R6XU25	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001670110\|UniProtKB=A0A1Y1HZ05	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_002220020\|UniProtKB=A0A1Y1IAM8	Klebsormidium nitens	LDO