PANTHER Gene Information   
Gene Symbol(s): Tsg101
Organism: Mus musculus
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: Tumor susceptibility gene 101 protein
Gene ID: MGI:106581
Protein ID: Q61187
Persistent Id: PTN000592465
Alternate Ids:
ENSMUST00000014546(Ensembl_TRS) BC085308(EMBL)
TS101(Synonym) Tsg101(Symbol)
22088(GeneID) ENSMUSP00000014546(Ensembl_PRO)
MGI:106581(MGI) ENSMUSG00000014402(Ensembl)
TS101_MOUSE(UniProtKB-ID) AAC53586(EMBL-CDS)
9789789(GI) NM_021884(refSeq)
Show All

PANTHER Classification
PANTHER Family: TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED (PTHR23306)
PANTHER Subfamily: TUMOR SUSCEPTIBILITY GENE 101 PROTEIN (PTHR23306:SF17)  
PANTHER GO-slim Molecular Function: ubiquitin binding
PANTHER GO-slim Biological Process: endosome to lysosome transport
PANTHER GO-slim Cellular Component: ESCRT I complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: virion binding, protein binding, ubiquitin protein ligase binding, protein homodimerization activity, ubiquitin binding, transcription corepressor activity, nuclear receptor coactivator activity, calcium-dependent protein binding, protein-containing complex binding
GO BP Complete: protein modification process, regulation of MAP kinase activity, negative regulation of epidermal growth factor-activated receptor activity, positive regulation of exosomal secretion, positive regulation of viral budding via host ESCRT complex, negative regulation of cell population proliferation, regulation of extracellular exosome assembly, protein transport, viral budding, endosome to lysosome transport, exosomal secretion, negative regulation of epidermal growth factor receptor signaling pathway, protein monoubiquitination, cell cycle, negative regulation of transcription by RNA polymerase II, cell division, extracellular transport, keratinocyte differentiation, viral release from host cell, regulation of cell growth, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, cell differentiation, positive regulation of ubiquitin-dependent endocytosis, regulation of cell cycle
GO CC Complete: ESCRT I complex, late endosome, nucleolus, plasma membrane, nucleus, early endosome, endosome, cytoskeleton, extracellular exosome, cytoplasm, membrane, cytosol, endosome membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Endosomal Sorting Complex Required For Transport (ESCRT), Vesicle-mediated transport, Membrane Trafficking

Orthologs