PANTHER Gene Information

Gene Symbol(s):

TSG101

Organism:

Pan troglodytes

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Gene Name:

Tumor susceptibility 101

Gene ID:

ENSPTRG00000003424.6

Protein ID:

A0A2I3SDN5

Persistent Id:

PTN009069831

Alternate Ids:

JAA00833(EMBL-CDS)	ENSPTRG00000003424(Ensembl)
451065(GeneID)	GABD01003086(EMBL)
1034087458(GI)	XP_016776037(refSeq)
A0A2I3SDN5_PANTR(UniProtKB-ID)	A0A2I3SDN5(Synonym)
ENSPTRT00000109681(Ensembl_TRS)	ENSPTRP00000075086(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED (PTHR23306)
PANTHER Subfamily:	TUMOR SUSCEPTIBILITY GENE 101 PROTEIN (PTHR23306:SF17)
PANTHER GO-slim Molecular Function:	ubiquitin binding
PANTHER GO-slim Biological Process:	endosome to lysosome transport
PANTHER GO-slim Cellular Component:	ESCRT I complex
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	virion binding, ubiquitin protein ligase binding, protein homodimerization activity, ubiquitin binding, transcription corepressor activity, calcium-dependent protein binding, protein-containing complex binding
GO BP Complete:	protein modification process, positive regulation of exosomal secretion, positive regulation of viral budding via host ESCRT complex, negative regulation of cell population proliferation, regulation of extracellular exosome assembly, protein transport, viral budding, endosome to lysosome transport, exosomal secretion, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of transcription by RNA polymerase II, extracellular transport, keratinocyte differentiation, viral release from host cell, regulation of cell growth, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, cell differentiation, positive regulation of ubiquitin-dependent endocytosis, regulation of cell cycle, multivesicular body assembly
GO CC Complete:	early endosome, endosome, extracellular exosome, cytoplasm, ESCRT I complex, membrane, late endosome, cytosol, nucleolus, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=15971\|UniProtKB=Q99816	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000010359.3\|UniProtKB=G3R4B1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014613.4\|UniProtKB=G7NDS4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=106581\|UniProtKB=Q61187	Mus musculus	LDO
RAT\|RGD=3909\|UniProtKB=Q6IRE4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013563.6\|UniProtKB=A3KN51	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000004362.4\|UniProtKB=A0A9L0RHA1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000028742.4\|UniProtKB=A0A337SU32	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016679.1\|UniProtKB=A0A8I3P8P4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006410.3\|UniProtKB=F7FD96	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008368.3\|UniProtKB=A0A6I8PK40	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000000062.4\|UniProtKB=A0A803TR58	Anolis carolinensis	LDO
XENLA\|Gene=tsg101.L\|UniProtKB=A0A8J1MW83	Xenopus laevis	O
XENLA\|Gene=MGC81040\|UniProtKB=Q6NUD5	Xenopus laevis	LDO
XENTR\|Gene=tsg101\|UniProtKB=A0A8J1JD66	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000023170.1\|UniProtKB=A0A3B3HBA2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-051127-21\|UniProtKB=Q2YDS7	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000030185.1\|UniProtKB=A0A3B3IPA0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-130530-542\|UniProtKB=E7F4Y8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030217-1\|UniProtKB=Q6IQ70	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000000710.1\|UniProtKB=W5LXD4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021102.1\|UniProtKB=H2XP92	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406970\|UniProtKB=A0A9J7KK24	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421770\|UniProtKB=A0A9J7LLM7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406656\|UniProtKB=A0A9J7HNB8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406596\|UniProtKB=A0A9J7HNJ2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105439760\|UniProtKB=A0A7M7P4V5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC763823\|UniProtKB=A0A7M7SZX9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00015658\|UniProtKB=O76258	Caenorhabditis elegans	LDO
DROME\|FlyBase=FBgn0036666\|UniProtKB=Q9VVA7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005934\|UniProtKB=Q7Q6B6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002425\|UniProtKB=D6WIH5	Tribolium castaneum	LDO
DAPPU\|Gene_ORFName=DAPPUDRAFT_65881\|UniProtKB=E9HTS3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014292\|UniProtKB=B7QIP7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185660\|UniProtKB=T1FN37	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244032\|UniProtKB=A7SAT5	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG33034\|UniProtKB=B3SBY4	Trichoplax adhaerens	LDO
YEAST\|SGD=S000000514\|UniProtKB=P25604	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAL006C\|UniProtKB=Q75EU1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000187259\|UniProtKB=Q59WF8	Candida albicans	LDO
EMENI\|EnsemblGenome=ANIA_02521\|UniProtKB=Q5BAA9	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G14380\|UniProtKB=Q4WYV3	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU05753\|UniProtKB=Q7S4R9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_10308\|UniProtKB=A7EY93	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_16164\|UniProtKB=Q0TWM8	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNC02240\|UniProtKB=Q5KKQ1	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11474\|UniProtKB=A0A0D1E2K5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_14838\|UniProtKB=E3KWF8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_90872\|UniProtKB=F4P9F9	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_194210\|UniProtKB=C4LZT6	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_131530\|UniProtKB=C4M9Z1	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_193530\|UniProtKB=B1N3Q7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_178530\|UniProtKB=C4LUR9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_135460\|UniProtKB=C4M9S4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0286797\|UniProtKB=Q54LJ3	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_155276\|UniProtKB=F0ZTJ6	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_0985\|UniProtKB=E9AEF7	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.3960\|UniProtKB=Q382W6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.01.5840\|UniProtKB=Q382B4	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_353480\|UniProtKB=A2EN70	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_193190\|UniProtKB=A2DH33	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_128690\|UniProtKB=A2E4C0	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00005706001\|UniProtKB=A0BV93	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009545001\|UniProtKB=A0CR15	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPS_23630\|UniProtKB=B5YNX5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GRU5_PHYRM\|UniProtKB=H3GRU5	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g144544v5\|UniProtKB=A0A2K3DV43	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g351050v5\|UniProtKB=A0A2K3DLC5	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00002p00269040\|UniProtKB=W1P3D6	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00051p00167090\|UniProtKB=U5D8G3	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00051p00166200\|UniProtKB=U5D5G4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_94G00270\|UniProtKB=A0A0K9NIP5	Zostera marina	O
MUSAM\|EnsemblGenome=Ma03_g32210\|UniProtKB=A0A804IIP9	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g14860\|UniProtKB=A0A804IPV1	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_024977mg\|UniProtKB=A0A0Q3TSZ9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G088803\|UniProtKB=A0A109NDP8	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb409970\|UniProtKB=A0A804RAY1	Zea mays	O
NELNU\|Gene_ORFName=HUJ06_007277\|UniProtKB=A0A1U8BD99	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_021168\|UniProtKB=A0A1U8BPA6	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_007278\|UniProtKB=A0A1U8B0X3	Nelumbo nucifera	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0423261\|UniProtKB=A0A251TIQ9	Helianthus annuus	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a020747mg\|UniProtKB=A0A022S1A0	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_08838\|UniProtKB=A0A2G2ZXL5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400019336\|UniProtKB=M1BPA9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc09g065770.1\|UniProtKB=A0A3Q7I4F2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107826539\|UniProtKB=A0A1S4D6J9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107788448\|UniProtKB=A0A1S3ZMX8	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi07g00060\|UniProtKB=F6HBJ5	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_B01481\|UniProtKB=A0A059D226	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00005351001\|UniProtKB=A0A078FYV7	Brassica napus	O
BRACM\|EnsemblGenome=Bra017097\|UniProtKB=M4DKR6	Brassica campestris	O
ARATH\|TAIR=locus=2040394\|UniProtKB=F4ITY4	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107955479\|UniProtKB=A0A1U8P6A7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107941651\|UniProtKB=A0A1U8MV58	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_004230\|UniProtKB=A0A061DQB8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g047127mg\|UniProtKB=A0A067FYR1	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_002G046200v3\|UniProtKB=A0A2K2BDE4	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_05G083600\|UniProtKB=A0A2C9VWV7	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0991540\|UniProtKB=B9S4R4	Ricinus communis	O
ZOSMR\|Gene_ORFName=ZOSMA_215G00100\|UniProtKB=A0A0K9PK70	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g28060\|UniProtKB=A0A804IH61	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g02590\|UniProtKB=A0A804KRU1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g06970\|UniProtKB=A0A804L544	Musa acuminata subsp. malaccensis	LDO
MAIZE\|EnsemblGenome=Zm00001eb259630\|UniProtKB=A0A804PQD0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0833300\|UniProtKB=Q6ESB7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g04460v3\|UniProtKB=A0A0Q3GQ74	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0523850\|UniProtKB=A0A287SQ79	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5A02G463000\|UniProtKB=A0A3B6KS41	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G475800\|UniProtKB=A0A3B6MZ42	Triticum aestivum	O
BRADI\|EnsemblGenome=BRADI_3g60837v3\|UniProtKB=A0A0Q3I8R7	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0504530\|UniProtKB=M0XLK7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G365300\|UniProtKB=A0A3B6MWR5	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G358900\|UniProtKB=A0A3B6LS51	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G356400\|UniProtKB=A0A3B6KKU0	Triticum aestivum	LDO
NELNU\|Gene=LOC104609678\|UniProtKB=A0A1U8B0V4	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104601457\|UniProtKB=A0A1U8A8W4	Nelumbo nucifera	O
SPIOL\|Gene=LOC110794291\|UniProtKB=A0A9R0ITM2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0175941\|UniProtKB=A0A251VU42	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700347150\|UniProtKB=A0A9R1X546	Lactuca sativa	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0819101\|UniProtKB=A0A251T572	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400172490\|UniProtKB=A0A9R1XFA3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a007629mg\|UniProtKB=A0A022Q0B4	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400002673\|UniProtKB=M0ZS40	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc09g009270.2\|UniProtKB=A0A3Q7HZ13	Solanum lycopersicum	O
TOBAC\|Gene=LOC107786494\|UniProtKB=A0A1S3ZGJ7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107767728\|UniProtKB=A0A1S3XQZ1	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_25806\|UniProtKB=A0A2G2YLT3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400008386\|UniProtKB=M1AFF3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g085590.1\|UniProtKB=A0A3Q7JGU6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107791870\|UniProtKB=A0A1S3ZYW5	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107828341\|UniProtKB=A0A1S4DCE8	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi15g00653\|UniProtKB=F6GV51	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi05g01184\|UniProtKB=F6GWC1	Vitis vinifera	LDO
BRACM\|EnsemblGenome=Bra023439\|UniProtKB=M4E3T6	Brassica campestris	LDO
ARATH\|TAIR=locus=2159113\|UniProtKB=Q9FFY6	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=DARMORV10_C02P33210.1\|UniProtKB=A0A078G4R5	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A02P20570.1\|UniProtKB=A0A078I9C5	Brassica napus	O
BRACM\|EnsemblGenome=Bra008248\|UniProtKB=M4CVK1	Brassica campestris	O
BRACM\|EnsemblGenome=Bra001451\|UniProtKB=M4CB71	Brassica campestris	O
ARATH\|TAIR=locus=2092477\|UniProtKB=Q9LHG8	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107955341\|UniProtKB=A0A1U8P639	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_044692\|UniProtKB=A0A061FR54	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g039489mg\|UniProtKB=A0A067DDL2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_003G191100v3\|UniProtKB=B9GXA7	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G034200v3\|UniProtKB=A0A2K2BRT6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_04G154600\|UniProtKB=A0A2C9W5C3	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_11G009300\|UniProtKB=A0A2C9UXE2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0621510\|UniProtKB=B9SHU4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_12G025300\|UniProtKB=I1LPI0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_11G099100\|UniProtKB=I1LIR0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g075250\|UniProtKB=G7JPJ7	Medicago truncatula	LDO
JUGRE\|Gene=LOC108989390\|UniProtKB=A0A2I4EGI7	Juglans regia	O
JUGRE\|Gene=LOC118344520\|UniProtKB=A0A6P9E011	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr14_02310\|UniProtKB=A0A2I4GZN3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G583320\|UniProtKB=A0A0A0KT64	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G048600\|UniProtKB=M5WZN4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_138144\|UniProtKB=D8TEQ5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_129226\|UniProtKB=D8T0J2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c27_3040\|UniProtKB=A0A2K1IAG6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c16_2240\|UniProtKB=A9TJ74	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0055s0078\|UniProtKB=A0A2R6WVC7	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0030s0083\|UniProtKB=A0A2R6X8B5	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003310130\|UniProtKB=A0A1Y1IDC2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000990220\|UniProtKB=A0A1Y1HW97	Klebsormidium nitens	LDO