PANTHER Gene Information

Gene Symbol(s):

NFATC1

Organism:

Pan troglodytes

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Gene Name:

Nuclear factor of activated T cells 1

Gene ID:

ENSPTRG00000010129.5

Protein ID:

A0A2I3RLV4

Persistent Id:

PTN000283326

Alternate Ids:

ENSPTRP00000065668(Ensembl_PRO)	A0A2I3RLV4_PANTR(UniProtKB-ID)
AACZ04007511(EMBL)	ENSPTRG00000010129(Ensembl)
ENSPTRT00000103041(Ensembl_TRS)	A0A2I3RLV4(Synonym)
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PANTHER Classification

PANTHER Family:	NFAT (PTHR12533)
PANTHER Subfamily:	NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1 (PTHR12533:SF5)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II calcineurin-mediated signaling cytokine production
PANTHER GO-slim Cellular Component:	transcription regulator complex
PANTHER protein class:	Rel homology transcription factor

Pathway Categories:

T cell activation

Nuclear factor of activated T cells

Inflammation mediated by chemokine and cytokine signaling pathway

Nuclear factor of activated T cells

Gonadotropin-releasing hormone receptor pathway

NFAT

B cell activation

Nuclear factor of activated T cells

Wnt signaling pathway

Nuclear factor of activated T-cells

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription factor binding, sequence-specific double-stranded DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	calcineurin-NFAT signaling cascade, regulation of DNA-templated transcription, cytokine production, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, transcription regulator complex, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7775\|UniProtKB=O95644	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000006879.3\|UniProtKB=A0A2I2ZWX0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022596.4\|UniProtKB=A0A5F8ATU2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=102469\|UniProtKB=O88942	Mus musculus	LDO
RAT\|RGD=2319357\|UniProtKB=D3ZE20	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000656.6\|UniProtKB=G3XCF6	Bos taurus	LDO
BOVIN\|Gene=NFATC1\|UniProtKB=P98201	Bos taurus	LDO
PIG\|Gene=NFATC1\|UniProtKB=O77638	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000004856.5\|UniProtKB=A0A287AA82	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000000884.6\|UniProtKB=A0A5F5XKD9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000073.1\|UniProtKB=A0A8I3MEU0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012018.4\|UniProtKB=A0A5F8GI94	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000030248.2\|UniProtKB=A0A6I8PFM4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010007252.1\|UniProtKB=A0A8V0XX53	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000941.4\|UniProtKB=A0A803TKT5	Anolis carolinensis	LDO
XENLA\|Gene=nfatc1.L\|UniProtKB=A0A8J0VIM0	Xenopus laevis	O
XENLA\|Gene=nfatc1.S\|UniProtKB=A0A1L8FSH1	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000008055.2\|UniProtKB=H2LVH0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000020716.2\|UniProtKB=H2N2H2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060503-677\|UniProtKB=Q19AW4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007875.1\|UniProtKB=W5MMH0	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118418168\|UniProtKB=A0A9J7LBQ8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC590859\|UniProtKB=A0A7M7LTI6	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0030505\|UniProtKB=A8JUV3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP013287\|UniProtKB=A0A453YYJ4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC014708\|UniProtKB=D6WNZ3	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW023728\|UniProtKB=B7QHC8	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243338\|UniProtKB=A7S787	Nematostella vectensis	O