PANTHER Gene Information

Gene Symbol(s):

MBD3

Organism:

Pan troglodytes

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Gene Name:

Methyl-CpG binding domain protein 3

Gene ID:

ENSPTRG00000010209.6

Protein ID:

H2R3B9

Persistent Id:

PTN000273811

Alternate Ids:

XP_009432566(refSeq)	JAA36812(EMBL-CDS)
H2R3B9_PANTR(UniProtKB-ID)	GABC01004172(EMBL)
694972082(GI)	ENSPTRP00000045258(Ensembl_PRO)
H2R3B9(Synonym)	455554(GeneID)
ENSPTRG00000010209(Ensembl)	ENSPTRT00000048384(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	METHYL-CPG BINDING PROTEIN, MBD (PTHR12396)
PANTHER Subfamily:	METHYL-CPG-BINDING DOMAIN PROTEIN 3 (PTHR12396:SF12)
PANTHER GO-slim Molecular Function:	nucleotide binding sequence-specific DNA binding
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II DNA methylation-dependent heterochromatin formation
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, methyl-CpG binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, chromatin remodeling, in utero embryonic development, tissue development, DNA methylation-dependent constitutive heterochromatin formation
GO CC Complete:	heterochromatin, nucleus, cytoplasm, NuRD complex, protein-containing complex, chromatin, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6918\|UniProtKB=O95983	Homo sapiens	LDO
MACMU\|Ensembl=ENSMMUG00000009014.4\|UniProtKB=I2CUX7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1333812\|UniProtKB=Q9Z2D8	Mus musculus	LDO
RAT\|RGD=1307389\|UniProtKB=F7EY92	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038409.3\|UniProtKB=A0A3Q1MJ47	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013435.5\|UniProtKB=F1SDI3	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000000763.5\|UniProtKB=A0A337SP15	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014226.1\|UniProtKB=A0A8I3P214	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004125.4\|UniProtKB=F6UWH4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003672.4\|UniProtKB=F7E6X2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027801.1\|UniProtKB=A0A8V1AFX7	Gallus gallus	LDO
XENLA\|Gene=mbd2.S\|UniProtKB=A0A1L8HRX9	Xenopus laevis	O
XENLA\|Gene=mbd2.L\|UniProtKB=A0A1L8I2S9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-493776\|UniProtKB=F6QZZ1	Xenopus tropicalis	O
XENLA\|Gene=mbd3.S\|UniProtKB=Q9PUM8	Xenopus laevis	LDO
XENLA\|Gene=LOC108712329\|UniProtKB=A0A8J0UUZ9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-491553\|UniProtKB=Q6DK69	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015235.2\|UniProtKB=H2MK75	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004850.2\|UniProtKB=A0A3B3H4J5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-9077\|UniProtKB=Q6TGX7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-9792\|UniProtKB=A0A2R8QPC3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006043.1\|UniProtKB=W5MFZ1	lepisosteus oculatus	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_126023\|UniProtKB=C3Y1X1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587853\|UniProtKB=A0A7M7HI36	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00023409\|UniProtKB=G5ECR1	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039281\|UniProtKB=Q4U5R6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00099236\|UniProtKB=Q5MK08	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0027950\|UniProtKB=A0A0B4KGZ0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003982\|UniProtKB=F5HM38	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003775\|UniProtKB=D6WEM7	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_310291\|UniProtKB=E9FT46	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_195138\|UniProtKB=E9GAX3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW010143\|UniProtKB=B7Q0K4	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185546\|UniProtKB=T1FMY9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g125309\|UniProtKB=A7SNU1	Nematostella vectensis	O