PANTHER Gene Information

Gene Symbol(s):

mbd2.S

Organism:

Xenopus laevis

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Gene Name:

Methyl-CpG binding domain protein 2 S homeolog isoform X1

Gene ID:

mbd2.S

Protein ID:

A0A1L8HRX9

Persistent Id:

PTN008995122

Alternate Ids:

1069317396(GI)	XM_018234748(refSeq)
399118(GeneID)	A0A1L8HRX9(Synonym)
A0A1L8HRX9_XENLA(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	METHYL-CPG BINDING PROTEIN, MBD (PTHR12396)
PANTHER Subfamily:	METHYL-CPG BINDING DOMAIN PROTEIN 2 (PTHR12396:SF58)
PANTHER GO-slim Molecular Function:	nucleotide binding sequence-specific DNA binding
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II DNA methylation-dependent heterochromatin formation
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, methyl-CpG binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, DNA methylation-dependent constitutive heterochromatin formation
GO CC Complete:	nucleus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6918\|UniProtKB=O95983	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010209.6\|UniProtKB=H2R3B9	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000009014.4\|UniProtKB=I2CUX7	Macaca mulatta	O
MOUSE\|MGI=MGI=1333812\|UniProtKB=Q9Z2D8	Mus musculus	O
RAT\|RGD=1307389\|UniProtKB=F7EY92	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000038409.3\|UniProtKB=A0A3Q1MJ47	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000013435.5\|UniProtKB=F1SDI3	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000000763.5\|UniProtKB=A0A337SP15	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845014226.1\|UniProtKB=A0A8I3P214	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004125.4\|UniProtKB=F6UWH4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003672.4\|UniProtKB=F7E6X2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027801.1\|UniProtKB=A0A8V1AFX7	Gallus gallus	O
XENTR\|Xenbase=XB-GENE-493776\|UniProtKB=F6QZZ1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015235.2\|UniProtKB=H2MK75	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004850.2\|UniProtKB=A0A3B3H4J5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-9077\|UniProtKB=Q6TGX7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-9792\|UniProtKB=A0A2R8QPC3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006043.1\|UniProtKB=W5MFZ1	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_126023\|UniProtKB=C3Y1X1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587853\|UniProtKB=A0A7M7HI36	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00023409\|UniProtKB=G5ECR1	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039281\|UniProtKB=Q4U5R6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00099236\|UniProtKB=Q5MK08	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0027950\|UniProtKB=A0A0B4KGZ0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003982\|UniProtKB=F5HM38	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003775\|UniProtKB=D6WEM7	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_310291\|UniProtKB=E9FT46	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_195138\|UniProtKB=E9GAX3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW010143\|UniProtKB=B7Q0K4	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185546\|UniProtKB=T1FMY9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g125309\|UniProtKB=A7SNU1	Nematostella vectensis	O