PANTHER Gene Information   
Gene Symbol(s): MBD3
Organism: Sus scrofa
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Gene Name: Methyl-CpG binding domain protein 3
Gene ID: ENSSSCG00000013435.5
Protein ID: F1SDI3
Persistent Id: PTN001391266
Alternate Ids:
F1SDI3(Synonym) ENSSSCT00000014679(Ensembl_TRS)
ENSSSCP00000014284(Ensembl_PRO) F1SDI3_PIG(UniProtKB-ID)
ENSSSCG00000013435(Ensembl)
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PANTHER Classification
PANTHER Family: METHYL-CPG BINDING PROTEIN, MBD (PTHR12396)
PANTHER Subfamily: METHYL-CPG-BINDING DOMAIN PROTEIN 3 (PTHR12396:SF12)  
PANTHER GO-slim Molecular Function: nucleotide binding
sequence-specific DNA binding
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
DNA methylation-dependent heterochromatin formation
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: methyl-CpG binding
GO BP Complete: negative regulation of transcription by RNA polymerase II, in utero embryonic development, tissue development, DNA methylation-dependent constitutive heterochromatin formation
GO CC Complete: heterochromatin, nucleus, cytoplasm, NuRD complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Transcriptional Regulation by TP53, Signal Transduction, Regulation of TP53 Activity through Acetylation, Regulation of TP53 Activity, Chromatin organization, Gene expression (Transcription), Regulation of PTEN gene transcription, RNA Polymerase I Promoter Clearance, RNA Polymerase I Transcription, Generic Transcription Pathway, RNA Polymerase I Transcription Initiation, Intracellular signaling by second messengers, HDACs deacetylate histones, PTEN Regulation, Chromatin modifying enzymes, PIP3 activates AKT signaling, RNA Polymerase II Transcription

Orthologs