PANTHER Gene Information   
Gene Symbol(s): FOXO3
Organism: Sus scrofa
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Gene Name: Forkhead box O3
Gene ID: ENSSSCG00000004387.5
Protein ID: F1RT23
Persistent Id: PTN001372013
Alternate Ids:
F1RT23_PIG(UniProtKB-ID) ENSSSCP00000004735(Ensembl_PRO)
ENSSSCT00000004849(Ensembl_TRS) F1RT23(Synonym)
HDA83586(EMBL-CDS) DQIR01128110(EMBL)
ENSSSCG00000004387(Ensembl)
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PANTHER Classification
PANTHER Family: FORKHEAD BOX PROTEIN O (PTHR45767)
PANTHER Subfamily: FORKHEAD BOX PROTEIN O3-RELATED (PTHR45767:SF4)  
PANTHER GO-slim Molecular Function: DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: nucleus
mitochondrial matrix
PANTHER protein class: winged helix/forkhead transcription factor
Pathway Categories: Insulin/IGF pathway-protein kinase B signaling cascade
   Forkhead transcription factor
PI3 kinase pathway
   FOXO
CCKR signaling map
   FOXO3
Interleukin signaling pathway
   Forkhead in Rhabdomyosarcoma-like 1
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase binding, chromatin DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, mitochondrial transcription factor activity, DNA-binding transcription repressor activity, RNA polymerase II-specific, beta-catenin binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: brain morphogenesis, positive regulation of miRNA transcription, extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of transcription by RNA polymerase II, positive regulation of erythrocyte differentiation, neuronal stem cell population maintenance, positive regulation of neuron apoptotic process, negative regulation of transcription by RNA polymerase II, ovulation from ovarian follicle, regulation of translation, positive regulation of regulatory T cell differentiation, initiation of primordial ovarian follicle growth, antral ovarian follicle growth, regulation of reactive oxygen species metabolic process, positive regulation of muscle atrophy, canonical Wnt signaling pathway, response to fatty acid, regulation of neural precursor cell proliferation, mitochondrial transcription, cellular response to glucose starvation, regulation of transcription by RNA polymerase II, negative regulation of canonical Wnt signaling pathway, positive regulation of autophagy, tumor necrosis factor-mediated signaling pathway, oocyte maturation, glucose homeostasis, DNA damage response, signal transduction by p53 class mediator, cellular response to oxidative stress, negative regulation of cell migration
GO CC Complete: nucleus, mitochondrial matrix, RNA polymerase II transcription repressor complex, cytosol, mitochondrial outer membrane, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signal Transduction, FLT3 Signaling, FOXO-mediated transcription of cell cycle genes, Cytokine Signaling in Immune system, Developmental Biology, Estrogen-dependent nuclear events downstream of ESR-membrane signaling, Signaling by NODAL, Gene expression (Transcription), Regulation of FOXO transcriptional activity by acetylation, FOXO-mediated transcription, MAPK family signaling cascades, Generic Transcription Pathway, Immune System, ESR-mediated signaling, Extra-nuclear estrogen signaling, MAPK6/MAPK4 signaling, Regulation of localization of FOXO transcription factors, Signaling by Nuclear Receptors, RNA Polymerase II Transcription

Orthologs