PANTHER Gene Information   
Gene Symbol(s): RBX1
Organism: Sus scrofa
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Gene Name: E3 ubiquitin-protein ligase RBX1
Gene ID: ENSSSCG00000034230.3
Protein ID: A0A287B501
Persistent Id: PTN004243466
Alternate Ids:
ENSSSCP00000051365(Ensembl_PRO) ENSSSCG00000034230(Ensembl)
A0A287B501(Synonym) ENSSSCT00000062866(Ensembl_TRS)
DQIR01197034(EMBL) HDB52511(EMBL-CDS)
A0A287B501_PIG(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: RING BOX (PTHR11210)
PANTHER Subfamily: E3 UBIQUITIN-PROTEIN LIGASE RBX1 (PTHR11210:SF61)  
PANTHER GO-slim Molecular Function: ubiquitin protein ligase activity
cullin family protein binding
PANTHER GO-slim Biological Process: ubiquitin-dependent protein catabolic process
protein ubiquitination
PANTHER GO-slim Cellular Component: nucleus
cullin-RING ubiquitin ligase complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, ubiquitin protein ligase activity, NEDD8 ligase activity, ubiquitin protein ligase binding, RNA polymerase II-specific DNA-binding transcription factor binding, ubiquitin-ubiquitin ligase activity, cullin family protein binding
GO BP Complete: negative regulation of type I interferon production, positive regulation of TORC1 signaling, protein K48-linked ubiquitination, negative regulation of response to oxidative stress, spermatogenesis, T cell activation, positive regulation of canonical NF-kappaB signal transduction, protein neddylation, positive regulation of protein autoubiquitination, protein monoubiquitination, ubiquitin-dependent protein catabolic process, ubiquitin-dependent protein catabolic process via the C-end degron rule pathway, cellular response to amino acid stimulus, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination
GO CC Complete: nucleus, cullin-RING ubiquitin ligase complex, Cul4A-RING E3 ubiquitin ligase complex, cytosol, Cul4B-RING E3 ubiquitin ligase complex, SCF ubiquitin ligase complex, Cul2-RING ubiquitin ligase complex, Cul3-RING ubiquitin ligase complex, Cul5-RING ubiquitin ligase complex, nucleoplasm, Cul7-RING ubiquitin ligase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Regulation of BACH1 activity, Signal Transduction, Prolactin receptor signaling, Metabolism of proteins, Post-translational protein modification, Gene expression (Transcription), Degradation of DVL, S Phase, Signaling by Interleukins, Signaling by Hedgehog, Cellular response to hypoxia, MAPK1/MAPK3 signaling, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha, Dual Incision in GG-NER, Synthesis of DNA, Gap-filling DNA repair synthesis and ligation in TC-NER, Orc1 removal from chromatin, Dual incision in TC-NER, TCF dependent signaling in response to WNT, Hedgehog 'off' state, GLI3 is processed to GLI3R by the proteasome, Cell Cycle, Mitotic, G2/M Transition, Regulation of RAS by GAPs, MAPK family signaling cascades, Cellular responses to stress, Degradation of GLI1 by the proteasome, Cell Cycle, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediated antigen processing & presentation, Regulation of RUNX2 expression and activity, Global Genome Nucleotide Excision Repair (GG-NER), Mitotic G2-G2/M phases, Cellular response to chemical stress, GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2, DNA Replication, Cytokine Signaling in Immune system, Adaptive Immune System, Interleukin-1 family signaling, Signaling by WNT, DNA Repair, Hedgehog 'on' state, DNA Damage Bypass, DNA Damage Recognition in GG-NER, Neddylation, Nucleotide Excision Repair, Formation of Incision Complex in GG-NER, RNA Polymerase II Transcription, Transcription-Coupled Nucleotide Excision Repair (TC-NER), Formation of TC-NER Pre-Incision Complex, Recognition of DNA damage by PCNA-containing replication complex, Nuclear events mediated by NFE2L2, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis, Degradation of beta-catenin by the destruction complex, Generic Transcription Pathway, Immune System, KEAP1-NFE2L2 pathway, Interleukin-1 signaling, Transcriptional regulation by RUNX2, Cellular responses to stimuli, RAF/MAP kinase cascade, Switching of origins to a post-replicative state

Orthologs