PANTHER Gene Information   
Gene Symbol(s): rbx1
Organism: Xenopus tropicalis
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Gene Name: E3 ubiquitin-protein ligase RBX1
Gene ID: XB-GENE-5779767
Protein ID: A0A6I8S8I3
Persistent Id: PTN008317780
Alternate Ids:
ENSXETT00000089638(Ensembl_TRS) A0A6I8S8I3(Synonym)
A0A6I8S8I3_XENTR(UniProtKB-ID) ENSXETP00000088979(Ensembl_PRO)
512836551(GI) XP_002934772(refSeq)
ENSXETG00000035313(Ensembl) 100379935(GeneID)
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PANTHER Classification
PANTHER Family: RING BOX (PTHR11210)
PANTHER Subfamily: E3 UBIQUITIN-PROTEIN LIGASE RBX1 (PTHR11210:SF61)  
PANTHER GO-slim Molecular Function: ubiquitin protein ligase activity
cullin family protein binding
PANTHER GO-slim Biological Process: ubiquitin-dependent protein catabolic process
protein ubiquitination
PANTHER GO-slim Cellular Component: nucleus
cullin-RING ubiquitin ligase complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ubiquitin-protein transferase activity, zinc ion binding, ubiquitin protein ligase activity, metal ion binding, cullin family protein binding
GO BP Complete: proteasome-mediated ubiquitin-dependent protein catabolic process, ubiquitin-dependent protein catabolic process, protein ubiquitination
GO CC Complete: nucleus, cytoplasm, cullin-RING ubiquitin ligase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: GLI3 is processed to GLI3R by the proteasome, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis, Gap-filling DNA repair synthesis and ligation in TC-NER, Dual incision in TC-NER, Hedgehog 'off' state, Gene expression (Transcription), Neddylation, Mitotic G2-G2/M phases, Cellular response to chemical stress, Cytokine Signaling in Immune system, Nuclear events mediated by NFE2L2, Generic Transcription Pathway, Adaptive Immune System, Global Genome Nucleotide Excision Repair (GG-NER), Switching of origins to a post-replicative state, Nucleotide Excision Repair, Interleukin-1 family signaling, Hedgehog 'on' state, GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2, Signaling by Hedgehog, Class I MHC mediated antigen processing & presentation, Orc1 removal from chromatin, Antigen processing: Ubiquitination & Proteasome degradation, Cellular responses to stimuli, Formation of Incision Complex in GG-NER, DNA Damage Recognition in GG-NER, Synthesis of DNA, KEAP1-NFE2L2 pathway, S Phase, RNA Polymerase II Transcription, TCF dependent signaling in response to WNT, Interleukin-1 signaling, DNA Repair, DNA Damage Bypass, Signal Transduction, Degradation of DVL, Cell Cycle, Transcriptional regulation by RUNX2, DNA Replication, Formation of TC-NER Pre-Incision Complex, Transcription-Coupled Nucleotide Excision Repair (TC-NER), Cell Cycle, Mitotic, Metabolism of proteins, Signaling by Interleukins, G2/M Transition, Post-translational protein modification, Prolactin receptor signaling, Immune System, Cellular responses to stress, Cellular response to hypoxia, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha, Dual Incision in GG-NER, Regulation of RUNX2 expression and activity, Recognition of DNA damage by PCNA-containing replication complex, Signaling by WNT, Degradation of GLI1 by the proteasome

Orthologs