PANTHER Gene Information

Gene Symbol(s):

Ltk

Organism:

Rattus norvegicus

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Gene Name:

Tyrosine-protein kinase receptor

Gene ID:

1309323

Protein ID:

A0A8I6GCV6

Persistent Id:

PTN000699422

Alternate Ids:

ENSRNOP00000085416(Ensembl_PRO)	ENSRNOG00000025130(Ensembl)
ENSRNOT00000099587(Ensembl_TRS)	A0A8I6GCV6_RAT(UniProtKB-ID)
1309323(RGD)	A0A8I6GCV6(Synonym)
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PANTHER Classification

PANTHER Family:	TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily:	LEUKOCYTE TYROSINE KINASE RECEPTOR (PTHR24416:SF294)
PANTHER GO-slim Molecular Function:	transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process:	positive regulation of kinase activity transmembrane receptor protein tyrosine kinase signaling pathway regulation of neuron differentiation regulation of cell population proliferation multicellular organism development
PANTHER GO-slim Cellular Component:	receptor complex plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, transmembrane receptor protein tyrosine kinase activity, protein kinase activity, receptor signaling protein tyrosine kinase activator activity
GO BP Complete:	cell population proliferation, multicellular organism development, cellular response to retinoic acid, negative regulation of apoptotic process, positive regulation of cardiac muscle cell apoptotic process, cell surface receptor protein tyrosine kinase signaling pathway, positive regulation of neuron projection development, positive regulation of kinase activity, regulation of neuron differentiation, regulation of cell population proliferation, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete:	membrane, receptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6721\|UniProtKB=P29376	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006948.7\|UniProtKB=H2Q982	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007006.3\|UniProtKB=G3QVS9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008170.4\|UniProtKB=F7HBY2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96840\|UniProtKB=P08923	Mus musculus	LDO
HORSE\|Ensembl=ENSECAG00000010591.4\|UniProtKB=A0A3Q2IEA9	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000000117.3\|UniProtKB=F6YBY8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014473.3\|UniProtKB=F6X759	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022572.1\|UniProtKB=A0A8V0ZP30	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013890.3\|UniProtKB=G1KPC7	Anolis carolinensis	O
CHICK\|Ensembl=ENSGALG00010017563.1\|UniProtKB=A0A8V0Z3S3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000008958.4\|UniProtKB=A0A803T8L6	Anolis carolinensis	O
XENLA\|Gene=LOC108699739\|UniProtKB=A0A1L8EZT5	Xenopus laevis	O
XENLA\|Gene=LOC108698980\|UniProtKB=A0A8J0TIV8	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000000055\|UniProtKB=F6UBP5	Xenopus tropicalis	O
XENLA\|Gene=LOC108717382\|UniProtKB=A0A8J1KS75	Xenopus laevis	O
XENLA\|Gene=LOC108716096\|UniProtKB=A0A8J1KNP1	Xenopus laevis	O
XENTR\|Gene=alk\|UniProtKB=A0A8J1JM32	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015434.2\|UniProtKB=H2MKV3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030616-115\|UniProtKB=F1QVU0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014716.1\|UniProtKB=W5NBY0	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000022549.1\|UniProtKB=A0A3B3HYV3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-031027-1\|UniProtKB=F8W3R9	Danio rerio	O
BRAFL\|Gene=LOC118415382\|UniProtKB=A0A9J7MQY2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587032\|UniProtKB=A0A7M7T3B4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441992\|UniProtKB=A0A7M7PPG6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC574978\|UniProtKB=A0A7M7N7T2	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004740\|UniProtKB=O76411	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG18982\|UniProtKB=A8XUH7	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0040505\|UniProtKB=Q7KJ08	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP012070\|UniProtKB=A0A453YYL0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002114\|UniProtKB=D6WGT3	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_309238\|UniProtKB=E9HB47	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_187767\|UniProtKB=E9G7E5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW000831\|UniProtKB=B7P3J2	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG164816\|UniProtKB=T1EVU6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85808\|UniProtKB=A7RLS3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG4397\|UniProtKB=B3RT13	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG12208\|UniProtKB=B3RT14	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG22855\|UniProtKB=B3RT16	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25143\|UniProtKB=A9UYJ2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_7936\|UniProtKB=A9UYJ1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_37833\|UniProtKB=A9V451	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_12183\|UniProtKB=A9VBG8	Monosiga brevicollis	O