PANTHER Gene Information   
Gene Symbol(s): rac3
Organism: Xenopus tropicalis
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Gene Name: Rac family small GTPase 3
Gene ID: XB-GENE-490195
Protein ID: A4IHY4
Persistent Id: PTN001178191
Alternate Ids:
A4IHY4_XENTR(UniProtKB-ID) NP_001093712(refSeq)
BC135751(EMBL) 154147747(GI)
ENSXETG00000033871(Ensembl) 100101726(GeneID)
A4IHY4(Synonym) AAI35752(EMBL-CDS)
ENSXETP00000095870(Ensembl_PRO) ENSXETT00000075866(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: RHO FAMILY GTPASE (PTHR24072)
PANTHER Subfamily: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3 (PTHR24072:SF325)  
PANTHER GO-slim Molecular Function: protein kinase binding
GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of leukocyte migration
Rac protein signal transduction
cell projection assembly
regulation of cell shape
cortical cytoskeleton organization
establishment or maintenance of cell polarity
regulation of actin cytoskeleton organization
motor neuron axon guidance
cell chemotaxis
PANTHER GO-slim Cellular Component: cytoskeleton
cytoplasmic vesicle
neuron projection
PANTHER protein class: small GTPase
Pathway Categories: VEGF signaling pathway
   Ras-related C3 botulinum toxin substrate
FGF signaling pathway
   Ras-related C3 botulinum toxin substrate
Integrin signalling pathway
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by Slit/Robo
   Ras-related C3 botulinum toxin substrate
Inflammation mediated by chemokine and cytokine signaling pathway
   Cell division cycle 42
Huntington disease
   Ras-related C3 botulinum toxin substrate
p38 MAPK pathway
   Ras-related C3 botulinum toxin substrate
B cell activation
   Ras-related C3 botulinum toxin substrate
T cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by netrin
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by semaphorins
   Ras-related C3 botulinum toxin substrate
Cytoskeletal regulation by Rho GTPase
   Ras-related C3 Botulinum toxin substrate 1
Ras Pathway
   Ras-related C3 botulinum toxin substrate
EGF receptor signaling pathway
   Ras-related C3 botulinum toxin substrate

GO MF Complete: GTP binding, protein kinase binding, GTPase activity
GO BP Complete: regulation of cell shape, Rac protein signal transduction, cortical cytoskeleton organization, regulation of actin cytoskeleton organization, motor neuron axon guidance, small GTPase-mediated signal transduction, cell projection assembly, establishment or maintenance of cell polarity, regulation of neutrophil migration, actin filament organization, cell chemotaxis
GO CC Complete: cytoskeleton, cytoplasmic vesicle, neuron projection, plasma membrane
Reactome Pathways: Signal Transduction, RHO GTPase cycle, Signaling by Rho GTPases, RAC3 GTPase cycle, Signaling by WNT, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, PCP/CE pathway, Beta-catenin independent WNT signaling