PANTHER Gene Information   
Gene Symbol(s): rac1A
Organism: Dictyostelium discoideum
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Gene Name: Rho-related protein rac1A
Gene ID: DDB_G0277869
Protein ID: P34144
Persistent Id: PTN000633487
Alternate Ids:
XP_642196(refSeq) Q9GPU0(AltAccession)
AAC37391(EMBL-CDS) AAFI02000023(EMBL)
rac1A(Symbol) EAL68107(Ensembl_TRS)
EAL68107(Ensembl_PRO) DDB_G0277869(dictyBase)
66816373(GI) 8621403(GeneID)
RAC1A(Synonym) DDB_G0277869(Ensembl)
RAC1A_DICDI(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: RHO FAMILY GTPASE (PTHR24072)
PANTHER Subfamily: RAS-RELATED PROTEIN RAC1-RELATED (PTHR24072:SF359)  
PANTHER GO-slim Molecular Function: protein kinase binding
GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of cell shape
cortical cytoskeleton organization
establishment or maintenance of cell polarity
regulation of actin cytoskeleton organization
PANTHER GO-slim Cellular Component: cell projection
cytoskeleton
cytoplasmic vesicle
PANTHER protein class: small GTPase
Pathway Categories: Integrin signalling pathway
   Ras-related C3 botulinum toxin substrate
FGF signaling pathway
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by Slit/Robo
   Ras-related C3 botulinum toxin substrate
Inflammation mediated by chemokine and cytokine signaling pathway
   Cell division cycle 42
Huntington disease
   Ras-related C3 botulinum toxin substrate
T cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by netrin
   Ras-related C3 botulinum toxin substrate
Cytoskeletal regulation by Rho GTPase
   Ras-related C3 Botulinum toxin substrate 1
Ras Pathway
   Ras-related C3 botulinum toxin substrate
EGF receptor signaling pathway
   Ras-related C3 botulinum toxin substrate

GO MF Complete: GTP binding, protein kinase binding, protein binding, GTPase activity
GO BP Complete: regulation of cell shape, Rac protein signal transduction, cortical cytoskeleton organization, regulation of actin cytoskeleton organization, signal transduction, small GTPase-mediated signal transduction, mitotic cytokinesis, establishment or maintenance of cell polarity, positive regulation of actin filament polymerization, actin filament organization, regulation of cell motility, regulation of mitotic cytokinesis
GO CC Complete: lipid droplet, cytoskeleton, perinuclear region of cytoplasm, cell leading edge cell cortex, cell cortex, phagocytic vesicle, cytoplasmic vesicle, cell trailing edge, phagocytic cup, cell projection, plasma membrane
Reactome Pathways: Hemostasis, RHOBTB2 GTPase cycle, EPH-Ephrin signaling, Signaling by PTK6, Cell death signalling via NRAGE, NRIF and NADE, RHO GTPases activate IQGAPs, Neutrophil degranulation, RHOBTB GTPase Cycle, Nervous system development, Regulation of actin dynamics for phagocytic cup formation, EPHB-mediated forward signaling, Fcgamma receptor (FCGR) dependent phagocytosis, CD28 co-stimulation, Signal transduction by L1, Factors involved in megakaryocyte development and platelet production, MAPK6/MAPK4 signaling, RHO GTPase Effectors, RHO GTPases Activate WASPs and WAVEs, PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases, RAC1 GTPase cycle, RHOBTB1 GTPase cycle, Developmental Biology, RAC3 GTPase cycle, RHO GTPase cycle, RHOH GTPase cycle, RAC2 GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RHOG GTPase cycle, Signal Transduction, Innate Immune System, Death Receptor Signaling, CD28 dependent Vav1 pathway, Costimulation by the CD28 family, Axon guidance, Signaling by Non-Receptor Tyrosine Kinases, Immune System, Adaptive Immune System, RHO GTPases activate PAKs, Signaling by Rho GTPases, MAPK family signaling cascades, NRAGE signals death through JNK, p75 NTR receptor-mediated signalling, L1CAM interactions