PANTHER Gene Information   
Gene Symbol(s): RAC1
Organism: Bos taurus
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Gene Name: Rac family small GTPase 1
Gene ID: ENSBTAG00000053390.1
Protein ID: A0A3Q1M7Y3
Persistent Id: PTN008604705
Alternate Ids:
A0A3Q1M7Y3(Synonym) ENSBTAG00000053390(Ensembl)
ENSBTAP00000064503(Ensembl_PRO) ENSBTAT00000067957(Ensembl_TRS)
A0A3Q1M7Y3_BOVIN(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: RHO FAMILY GTPASE (PTHR24072)
PANTHER Subfamily: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (RHO FAMILY, SMALL GTP BINDING PROTEIN RAC1) (PTHR24072:SF105)  
PANTHER GO-slim Molecular Function: protein kinase binding
GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of leukocyte migration
Rac protein signal transduction
cell projection assembly
regulation of cell shape
cortical cytoskeleton organization
establishment or maintenance of cell polarity
regulation of actin cytoskeleton organization
motor neuron axon guidance
cell chemotaxis
PANTHER GO-slim Cellular Component: dendritic spine
cytoskeleton
cytoplasmic vesicle
PANTHER protein class: small GTPase
Pathway Categories: FGF signaling pathway
   Ras-related C3 botulinum toxin substrate
Integrin signalling pathway
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by Slit/Robo
   Ras-related C3 botulinum toxin substrate
Inflammation mediated by chemokine and cytokine signaling pathway
   Cell division cycle 42
p38 MAPK pathway
   Ras-related C3 botulinum toxin substrate
Huntington disease
   Ras-related C3 botulinum toxin substrate
B cell activation
   Ras-related C3 botulinum toxin substrate
T cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by netrin
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by semaphorins
   Ras-related C3 botulinum toxin substrate
Cytoskeletal regulation by Rho GTPase
   Ras-related C3 Botulinum toxin substrate 1
Ras Pathway
   Ras-related C3 botulinum toxin substrate
EGF receptor signaling pathway
   Ras-related C3 botulinum toxin substrate

GO MF Complete: -
GO BP Complete: -
GO CC Complete: -
Reactome Pathways: CD28 co-stimulation, FCERI mediated MAPK activation, Regulation of actin dynamics for phagocytic cup formation, Signal transduction by L1, Adaptive Immune System, EPH-ephrin mediated repulsion of cells, CD28 dependent Vav1 pathway, Intracellular signaling by second messengers, Signaling by Non-Receptor Tyrosine Kinases, Platelet activation, signaling and aggregation, MAPK6/MAPK4 signaling, Signal Transduction, Death Receptor Signaling, Innate Immune System, Hemostasis, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, DCC mediated attractive signaling, Ephrin signaling, MET activates RAP1 and RAC1, Negative regulation of the PI3K/AKT network, RHO GTPase Effectors, EPHB-mediated forward signaling, Fcgamma receptor (FCGR) dependent phagocytosis, PIP3 activates AKT signaling, MET promotes cell motility, Sema4D in semaphorin signaling, RHO GTPase cycle, Immune System, Signaling by MET, Developmental Biology, Activated NTRK2 signals through FYN, Azathioprine ADME, Signaling by SCF-KIT, p75 NTR receptor-mediated signalling, Drug ADME, DSCAM interactions, Sema3A PAK dependent Axon repulsion, VEGFA-VEGFR2 Pathway, EPH-Ephrin signaling, Signaling by WNT, Signaling by Rho GTPases, Factors involved in megakaryocyte development and platelet production, Costimulation by the CD28 family, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, NTRK2 activates RAC1, Beta-catenin independent WNT signaling, Neutrophil degranulation, Signaling by NTRKs, RHO GTPases Activate WASPs and WAVEs, RHO GTPases activate KTN1, PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases, Signaling by PTK6, RHO GTPases activate PAKs, GPVI-mediated activation cascade, Netrin-1 signaling, Signaling by NTRK2 (TRKB), RHO GTPases Activate NADPH Oxidases, Axon guidance, RHO GTPases activate CIT, Signaling by Receptor Tyrosine Kinases, VEGFR2 mediated vascular permeability, Semaphorin interactions, RAC1 GTPase cycle, Cell death signalling via NRAGE, NRIF and NADE, RHO GTPases activate PKNs, DAP12 interactions, DAP12 signaling, RHO GTPases Activate Formins, MAPK family signaling cascades, PCP/CE pathway, L1CAM interactions, NRAGE signals death through JNK, RHO GTPases activate IQGAPs, Fc epsilon receptor (FCERI) signaling, Signaling by VEGF, Nervous system development, Sema4D mediated inhibition of cell attachment and migration