PANTHER Gene Information   
Gene Symbol(s): rac1
Organism: Danio rerio
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Gene Name: Rac family small GTPase 1a
Gene ID: ZDB-GENE-030131-5415
Protein ID: Q7ZSZ9
Persistent Id: PTN000633344
Alternate Ids:
327204(GeneID) AAH71548(EMBL-CDS)
ENSDARP00000096950(Ensembl_PRO) ZDB-GENE-030131-5415(ZFIN)
Q7ZSZ9(Synonym) ENSDART00000106172(Ensembl_TRS)
ENSDARG00000074849(Ensembl) BC044538(EMBL)
NP_956065(refSeq) 47938081(GI)
Q7ZSZ9_DANRE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: RHO FAMILY GTPASE (PTHR24072)
PANTHER Subfamily: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (RHO FAMILY, SMALL GTP BINDING PROTEIN RAC1) (PTHR24072:SF105)  
PANTHER GO-slim Molecular Function: protein kinase binding
GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of leukocyte migration
Rac protein signal transduction
cell projection assembly
regulation of cell shape
cortical cytoskeleton organization
establishment or maintenance of cell polarity
regulation of actin cytoskeleton organization
motor neuron axon guidance
cell chemotaxis
PANTHER GO-slim Cellular Component: dendritic spine
cytoskeleton
cytoplasmic vesicle
PANTHER protein class: small GTPase
Pathway Categories: FGF signaling pathway
   Ras-related C3 botulinum toxin substrate
Integrin signalling pathway
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by Slit/Robo
   Ras-related C3 botulinum toxin substrate
Inflammation mediated by chemokine and cytokine signaling pathway
   Cell division cycle 42
p38 MAPK pathway
   Ras-related C3 botulinum toxin substrate
Huntington disease
   Ras-related C3 botulinum toxin substrate
B cell activation
   Ras-related C3 botulinum toxin substrate
T cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by netrin
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by semaphorins
   Ras-related C3 botulinum toxin substrate
Cytoskeletal regulation by Rho GTPase
   Ras-related C3 Botulinum toxin substrate 1
Ras Pathway
   Ras-related C3 botulinum toxin substrate
EGF receptor signaling pathway
   Ras-related C3 botulinum toxin substrate

GO MF Complete: nucleotide binding, GTP binding, protein kinase binding, GTPase activity, G protein activity
GO BP Complete: regulation of cell shape, Rac protein signal transduction, motor neuron axon guidance, small GTPase-mediated signal transduction, cell projection assembly, establishment or maintenance of cell polarity, myoblast fusion, regulation of neutrophil migration, actin filament organization, cell chemotaxis, cortical cytoskeleton organization, regulation of actin cytoskeleton organization, cell migration involved in gastrulation, neutrophil chemotaxis
GO CC Complete: cytoskeleton, dendritic spine, cytoplasmic vesicle, plasma membrane
Reactome Pathways: Adaptive Immune System, Netrin-1 signaling, EPH-ephrin mediated repulsion of cells, Intracellular signaling by second messengers, Beta-catenin independent WNT signaling, Neutrophil degranulation, Axon guidance, NRAGE signals death through JNK, Nervous system development, p75 NTR receptor-mediated signalling, Signal Transduction, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, EPH-Ephrin signaling, Semaphorin interactions, DCC mediated attractive signaling, RHO GTPase Effectors, Cell death signalling via NRAGE, NRIF and NADE, RHO GTPases activate PAKs, Immune System, RHO GTPases activate PKNs, Negative regulation of the PI3K/AKT network, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Signaling by Non-Receptor Tyrosine Kinases, MAPK family signaling cascades, RHO GTPases Activate Formins, Sema3A PAK dependent Axon repulsion, RHO GTPases Activate NADPH Oxidases, PIP3 activates AKT signaling, RHO GTPase cycle, Signaling by Receptor Tyrosine Kinases, Death Receptor Signaling, Hemostasis, VEGFA-VEGFR2 Pathway, Factors involved in megakaryocyte development and platelet production, PCP/CE pathway, Signaling by VEGF, Signaling by WNT, Signaling by Rho GTPases, RHO GTPases activate IQGAPs, Innate Immune System, RAC1 GTPase cycle, CD28 co-stimulation, PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases, MAPK6/MAPK4 signaling, Costimulation by the CD28 family, Signaling by PTK6, CD28 dependent Vav1 pathway, Developmental Biology