PANTHER Gene Information   
Gene Symbol(s): RAC1
Organism: Anolis carolinensis
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Gene Name: Rac family small GTPase 1
Gene ID: ENSACAG00000012949.4
Protein ID: A0A803SPE4
Persistent Id: PTN001530279
Alternate Ids:
1033377090(GI) ENSACAG00000012949(Ensembl)
ENSACAT00000040626(Ensembl_TRS) XM_016997506(refSeq)
ENSACAP00000024834(Ensembl_PRO) A0A803SPE4(Synonym)
100561917(GeneID) A0A803SPE4_ANOCA(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: RHO FAMILY GTPASE (PTHR24072)
PANTHER Subfamily: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (PTHR24072:SF395)  
PANTHER GO-slim Molecular Function: protein kinase binding
GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of leukocyte migration
Rac protein signal transduction
cell projection assembly
regulation of cell shape
cortical cytoskeleton organization
establishment or maintenance of cell polarity
regulation of actin cytoskeleton organization
motor neuron axon guidance
cell chemotaxis
PANTHER GO-slim Cellular Component: dendritic spine
cytoskeleton
cytoplasmic vesicle
PANTHER protein class: small GTPase
Pathway Categories: VEGF signaling pathway
   Ras-related C3 botulinum toxin substrate
FGF signaling pathway
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by Slit/Robo
   Ras-related C3 botulinum toxin substrate
Huntington disease
   Ras-related C3 botulinum toxin substrate
p38 MAPK pathway
   Ras-related C3 botulinum toxin substrate
B cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by semaphorins
   Ras-related C3 botulinum toxin substrate
Cytoskeletal regulation by Rho GTPase
   Ras-related C3 Botulinum toxin substrate 1
CCKR signaling map
   RAC1-GTP
Inflammation mediated by chemokine and cytokine signaling pathway
   Ras-related C3 botulinum toxin substrate
Integrin signalling pathway
   Ras-related C3 botulinum toxin substrate
Inflammation mediated by chemokine and cytokine signaling pathway
   Cell division cycle 42
Gonadotropin-releasing hormone receptor pathway
   Rac1
T cell activation
   Ras-related C3 botulinum toxin substrate
Axon guidance mediated by netrin
   Ras-related C3 botulinum toxin substrate
Ras Pathway
   Ras-related C3 botulinum toxin substrate
EGF receptor signaling pathway
   Ras-related C3 botulinum toxin substrate
CCKR signaling map
   RAC1-GDP

GO MF Complete: GTP binding, protein kinase binding, GTPase activity, thioesterase binding, hydrolase activity, enzyme binding, protein-containing complex binding
GO BP Complete: regulation of cell shape, Rac protein signal transduction, motor neuron axon guidance, cell projection assembly, regulation of cell size, regulation of respiratory burst, positive regulation of bicellular tight junction assembly, actin filament organization, regulation of stress fiber assembly, sphingosine-1-phosphate receptor signaling pathway, cell chemotaxis, cortical cytoskeleton organization, negative regulation of interleukin-23 production, substrate adhesion-dependent cell spreading, positive regulation of cell-substrate adhesion, positive regulation of microtubule polymerization, localization within membrane, positive regulation of endothelial cell migration, cell migration, positive regulation of lamellipodium assembly, regulation of lamellipodium assembly, small GTPase-mediated signal transduction, positive regulation of neutrophil chemotaxis, establishment or maintenance of cell polarity, regulation of neutrophil migration, positive regulation of substrate adhesion-dependent cell spreading, hepatocyte growth factor receptor signaling pathway, cell motility, regulation of actin cytoskeleton organization, positive regulation of focal adhesion assembly, ruffle assembly, positive regulation of stress fiber assembly, ruffle organization, negative regulation of fibroblast migration, lamellipodium assembly, regulation of cell migration, actin cytoskeleton organization
GO CC Complete: cytoplasmic ribonucleoprotein granule, synapse, actin filament, cell projection, plasma membrane, nucleus, dendrite, trans-Golgi network, cytoskeleton, postsynapse, cytoplasm, melanosome, cell cortex, dendritic spine, cytoplasmic vesicle, ruffle membrane, recycling endosome membrane, glutamatergic synapse, lamellipodium
Reactome Pathways: -