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comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

poc1b

Organism:

Xenopus tropicalis

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Guanine nucleotide binding protein (G protein), beta 5

Gene ID:

XB-GENE-944930

Protein ID:

F7EBE7

Persistent Id:

PTN008571555

Alternate Ids:

F7EBE7_XENTR(UniProtKB-ID)	733883(GeneID)
847110305(GI)	XP_012814295(refSeq)
F7EBE7(Synonym)	ENSXETG00000020741(Ensembl)
ENSXETP00000044829(Ensembl_PRO)	ENSXETT00000044829(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily:	GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 (PTHR19850:SF36)
PANTHER GO-slim Molecular Function:	signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process:	G protein-coupled receptor signaling pathway dopamine receptor signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane protein complex extrinsic component of membrane cytoplasm catalytic complex cytoplasmic side of plasma membrane
PANTHER protein class:	heterotrimeric G-protein

Pathway Categories:

Beta3 adrenergic receptor signaling pathway

G-Protein

Thyrotropin-releasing hormone receptor signaling pathway

G-Protein

Histamine H1 receptor mediated signaling pathway

G-Protein

5HT1 type receptor mediated signaling pathway

G-protein

5HT4 type receptor mediated signaling pathway

G-protein

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

Gq-protein

Gonadotropin-releasing hormone receptor pathway

Gbeta

Beta1 adrenergic receptor signaling pathway

G-Protein

PI3 kinase pathway

G protein, beta and gamma subunit

5HT2 type receptor mediated signaling pathway

G-protein

Enkephalin release

Gi-protein

Opioid proenkephalin pathway

G-protein

Enkephalin release

Gs-protein

Angiotensin II-stimulated signaling through G proteins and beta-arrestin

G-protein, beta subunit

Opioid prodynorphin pathway

G-protein

Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction

G protein, beta subunit 5L

Beta2 adrenergic receptor signaling pathway

G-Protein

Histamine H2 receptor mediated signaling pathway

G-Protein

Opioid proopiomelanocortin pathway

G-protein

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

Gi-protein

Metabotropic glutamate receptor group III pathway

Gi-protein

Cortocotropin releasing factor receptor signaling pathway

G-Protein

Metabotropic glutamate receptor group II pathway

G-protein

Oxytocin receptor mediated signaling pathway

G-Protein

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	signaling receptor complex adaptor activity
GO BP Complete:	G protein-coupled receptor signaling pathway, cilium assembly, centriole replication, cell projection organization, G protein-coupled dopamine receptor signaling pathway
GO CC Complete:	heterotrimeric G-protein complex, cytoskeleton, cytoplasm, centriole, ciliary basal body

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Platelet homeostasis, G alpha (12/13) signalling events, Metabolism, G beta:gamma signalling through CDC42, GPER1 signaling, G beta:gamma signalling through PLC beta, Ca2+ pathway, G alpha (q) signalling events, Hemostasis, GABA B receptor activation, GABA receptor activation, Regulation of insulin secretion, ESR-mediated signaling, Transport of small molecules, G protein gated Potassium channels, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Protein folding, Thromboxane signalling through TP receptor, Neuronal System, Inwardly rectifying K+ channels, Transmission across Chemical Synapses, Signaling by Nuclear Receptors, Neurotransmitter receptors and postsynaptic signal transmission, Activation of kainate receptors upon glutamate binding, Platelet activation, signaling and aggregation, G-protein beta:gamma signalling, Signaling by GPCR, Signal Transduction, Beta-catenin independent WNT signaling, Metabolism of proteins, Prostacyclin signalling through prostacyclin receptor, Potassium Channels, Activation of GABAB receptors, ADP signalling through P2Y purinoceptor 12, Thrombin signalling through proteinase activated receptors (PARs), G beta:gamma signalling through BTK, G beta:gamma signalling through PI3Kgamma, G-protein activation, Aquaporin-mediated transport, Vasopressin regulates renal water homeostasis via Aquaporins, G alpha (s) signalling events, Integration of energy metabolism, G alpha (z) signalling events, Presynaptic function of Kainate receptors, G alpha (i) signalling events, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, Signal amplification, ADP signalling through P2Y purinoceptor 1, Extra-nuclear estrogen signaling, Adrenaline,noradrenaline inhibits insulin secretion, GPCR downstream signalling, Activation of G protein gated Potassium channels, Chaperonin-mediated protein folding, Signaling by WNT, Opioid Signalling

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4401\|UniProtKB=O14775	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007084.6\|UniProtKB=H2Q9G5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001028.3\|UniProtKB=G3QFE2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017374.4\|UniProtKB=F7H6T7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=101848\|UniProtKB=P62881	Mus musculus	LDO
RAT\|RGD=620759\|UniProtKB=P62882	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003762.6\|UniProtKB=A0A3S5ZPL0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000004622.5\|UniProtKB=A0A5G2QFC3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000042921.2\|UniProtKB=A0A9L0RHF4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012572.6\|UniProtKB=A0A337SPY9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026999.1\|UniProtKB=A0A8I3PV05	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001948.4\|UniProtKB=F6VJS6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000047160.1\|UniProtKB=A0A6I8P7Y0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020973.1\|UniProtKB=A0A8V0ZF95	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010868.4\|UniProtKB=H9GH07	Anolis carolinensis	LDO
XENLA\|Gene=LOC108711385\|UniProtKB=A0A8J1MLR0	Xenopus laevis	O
XENLA\|Gene=gnb5.S\|UniProtKB=A0A1L8GT33	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000012789.2\|UniProtKB=H2MBT7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1712\|UniProtKB=Q6PBY0	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000005515.2\|UniProtKB=H2LLM8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070112-342\|UniProtKB=A1L271	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013355.1\|UniProtKB=W5N753	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000022015.1\|UniProtKB=H2XZV4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118409840\|UniProtKB=A0A9J7KN65	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115918397\|UniProtKB=A0A7M7RHY4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001680\|UniProtKB=Q20636	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00032939\|UniProtKB=A8XEK3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00100651\|UniProtKB=A0A2A6BLQ9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0030011\|UniProtKB=Q9W3J1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010318\|UniProtKB=A0A1S4H3M9	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012525\|UniProtKB=Q7PD60	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008821\|UniProtKB=D6WR87	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_190617\|UniProtKB=E9FT66	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014555\|UniProtKB=B7QIE4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG115679\|UniProtKB=T1EG99	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244849\|UniProtKB=A7SF63	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG49804\|UniProtKB=B3RJH0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_38561\|UniProtKB=A9V8R6	Monosiga brevicollis	O
YEAST\|SGD=S000005738\|UniProtKB=P18851	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR097W\|UniProtKB=Q75C20	Eremothecium gossypii	O
CANAL\|CGD=CAL0000180995\|UniProtKB=A0A1D8PH43	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E01364g\|UniProtKB=Q6C7F0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00081\|UniProtKB=Q5BH99	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G12210\|UniProtKB=Q4WVI4	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU00440\|UniProtKB=F5HH30	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03482\|UniProtKB=A7EDU2	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_16044\|UniProtKB=Q0TWX6	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC32H8.07\|UniProtKB=Q10282	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03081\|UniProtKB=B6K398	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CND03830\|UniProtKB=Q5KI86	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00703\|UniProtKB=A0A0D1EDL6	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_03727\|UniProtKB=E3K0E6	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_17943\|UniProtKB=F4PD00	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_000240\|UniProtKB=C4LZ87	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0277143\|UniProtKB=P36408	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_93216\|UniProtKB=F1A421	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00013334001\|UniProtKB=A0D4A1	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_37124\|UniProtKB=B8CBT0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G9J9_PHYRM\|UniProtKB=H3G9J9	Phytophthora ramorum	O
AMBTC\|EnsemblGenome=AMTR_s00059p00065870\|UniProtKB=U5D7V0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_123G00150\|UniProtKB=A0A0K9Q2F3	Zostera marina	O
MUSAM\|EnsemblGenome=Ma10_g28650\|UniProtKB=A0A804L1D0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g09460\|UniProtKB=A0A804KHQ7	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g33350\|UniProtKB=A0A804JN72	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_036161mg\|UniProtKB=K4ABA4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G142100\|UniProtKB=C5WQA4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb052290\|UniProtKB=P49178	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0669200\|UniProtKB=Q40687	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g12820v3\|UniProtKB=I1GPP8	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0333760\|UniProtKB=A0A8I6X8T9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4B02G019900\|UniProtKB=W5EP05	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G294000\|UniProtKB=A0A3B6HX51	Triticum aestivum	O
NELNU\|Gene=LOC104601886\|UniProtKB=A0A1U8ALW3	Nelumbo nucifera	O
NELNU\|Gene=LOC104595714\|UniProtKB=A0A1U8A019	Nelumbo nucifera	O
SPIOL\|Gene=LOC110805508\|UniProtKB=A0A9R0KCQ8	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0547531\|UniProtKB=A0A251SUN2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0453161\|UniProtKB=A0A251TNA1	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500271450\|UniProtKB=A0A9R1X988	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C700377650\|UniProtKB=A0A9R1X4H2	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008244mg\|UniProtKB=A0A022RC09	Erythranthe guttata	O
SOLTU\|Gene=GB1\|UniProtKB=P93563	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG401000722\|UniProtKB=M0ZJA5	Solanum tuberosum	O
TOBAC\|Gene=LOC107760597\|UniProtKB=A0A1S3X384	Nicotiana tabacum	O
TOBAC\|Gene=LOC107820634\|UniProtKB=A0A1S4CNA1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107776663\|UniProtKB=A0A1S3YJ35	Nicotiana tabacum	O
TOBAC\|Gene=GBB2_TOBAC\|UniProtKB=P93398	Nicotiana tabacum	O
TOBAC\|Gene=GBB3_TOBAC\|UniProtKB=Q40507	Nicotiana tabacum	O
TOBAC\|Gene=GBB1_TOBAC\|UniProtKB=P93397	Nicotiana tabacum	O
TOBAC\|Gene=LOC107793273\|UniProtKB=A0A1S4A324	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi03g00343\|UniProtKB=D7TQ08	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I01264\|UniProtKB=A0A059APK8	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00083586001\|UniProtKB=A0A078I813	Brassica napus	O
BRACM\|EnsemblGenome=Bra034628\|UniProtKB=M4F0N3	Brassica campestris	O
BRACM\|EnsemblGenome=Bra017658\|UniProtKB=M4DMC5	Brassica campestris	O
BRACM\|EnsemblGenome=Bra011536\|UniProtKB=M4D4X9	Brassica campestris	O
ARATH\|TAIR=locus=2139489\|UniProtKB=P49177	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107894229\|UniProtKB=A0A1U8IF42	Gossypium hirsutum	O
GOSHI\|Gene=LOC107927977\|UniProtKB=A0A1U8LMB9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107908775\|UniProtKB=A0A1U8JTC9	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_006901\|UniProtKB=A0A061E6Y1	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g016458mg\|UniProtKB=A0A067E1X3	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_009G115300v3\|UniProtKB=B9HRN9	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G153700v3\|UniProtKB=B9H0Q0	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_17G100500\|UniProtKB=A0A2C9U6P8	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_15G164000\|UniProtKB=A0A2C9UGN5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1674940\|UniProtKB=B9RBE4	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_11G118500\|UniProtKB=I1LJE1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_12G043900\|UniProtKB=I1LQ45	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G013000\|UniProtKB=I1K777	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_04G013100\|UniProtKB=C6THC3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g116500\|UniProtKB=G7J6K3	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr16_18100\|UniProtKB=A0A2I4FZ53	Juglans regia	O
JUGRE\|EnsemblGenome=Jr13_07280\|UniProtKB=A0A2I4GVB3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_7G267960\|UniProtKB=A0A0A0K4B7	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_8G098100\|UniProtKB=M5VM49	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_142121\|UniProtKB=D8QYQ4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_440157\|UniProtKB=D8R8Y3	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c2_6210\|UniProtKB=A0A2K1L0G1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c1_35990\|UniProtKB=A0A2K1LB50	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0056s0121\|UniProtKB=A0A2R6WUZ6	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_008660040\|UniProtKB=A0A1Y1IMH6	Klebsormidium nitens	O