PANTHER Gene Information   
Gene Symbol(s): MCM5
Organism: Saccharomyces cerevisiae
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Gene Name: Minichromosome maintenance protein 5
Gene ID: S000004264
Protein ID: P29496
Persistent Id: PTN000180204
Alternate Ids:
YLR274W_mRNA(Ensembl_TRS) BK006945(EMBL)
3.6.4.12(EC) YEAST:G3O-32373-MON(BioCyc)
988086956(GI) S000004264(SGD)
D6VYS1(AltAccession) MCM5_YEAST(UniProtKB-ID)
AAB67364(EMBL-CDS) YLR274W(Ensembl)
MCM5(Symbol) NM_001182161(refSeq)
YLR274W(Ensembl_PRO) Cell division control protein 46(Synonym)
850980(GeneID)
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PANTHER Classification
PANTHER Family: DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER (PTHR11630)
PANTHER Subfamily: DNA REPLICATION LICENSING FACTOR MCM5 (PTHR11630:SF42)  
PANTHER GO-slim Molecular Function: single-stranded DNA binding
3'-5' DNA helicase activity
single-stranded DNA helicase activity
PANTHER GO-slim Biological Process: DNA replication initiation
double-strand break repair via break-induced replication
PANTHER GO-slim Cellular Component: MCM complex
nucleus
PANTHER protein class: DNA metabolism protein
Pathway Categories: Apoptosis signaling pathway
   Heat shock protein 70
Parkinson disease
   Heat shock protein 70
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, zinc ion binding, double-stranded DNA helicase activity, helicase activity, four-way junction helicase activity, chromatin binding, forked DNA-dependent helicase activity, 3'-5' DNA helicase activity, cohesin loader activity, single-stranded DNA binding, DNA binding, DNA replication origin binding, ATP binding, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, ATP-dependent H3-H4 histone complex chaperone activity, single-stranded 3'-5' DNA helicase activity, single-stranded DNA helicase activity, chromatin extrusion motor activity, hydrolase activity
GO BP Complete: DNA replication initiation, nuclear DNA replication, double-strand break repair via break-induced replication, DNA replication, regulation of DNA-templated DNA replication initiation, pre-replicative complex assembly involved in nuclear cell cycle DNA replication, DNA unwinding involved in DNA replication, premeiotic DNA replication, transcription elongation by RNA polymerase II, subtelomeric heterochromatin formation, heterochromatin formation, DNA duplex unwinding, chromatin looping
GO CC Complete: chromosome, telomeric region, nucleus, nuclear pre-replicative complex, CMG complex, cytoplasm, DNA replication preinitiation complex, replication fork protection complex, MCM complex, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G2/M Checkpoints, Switching of origins to a post-replicative state, DNA Replication Pre-Initiation, Activation of ATR in response to replication stress, Cell Cycle, Mitotic, Cell Cycle Checkpoints, Mitotic G1 phase and G1/S transition, S Phase, Assembly of the pre-replicative complex, Activation of the pre-replicative complex, G1/S Transition, Synthesis of DNA, Cell Cycle, DNA Replication

Orthologs