PANTHER Gene Information   
Gene Symbol(s): GNB2
Organism: Bos taurus
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Gene Name: Guanine nucleotide-binding protein G(I)_G(S)_G(T) subunit beta-2
Gene ID: ENSBTAG00000006495
Protein ID: P11017
Persistent Id: PTN000457574
Alternate Ids:
M16480(EMBL) M36431(EMBL)
GNB2(Symbol) ENSBTAT00000008508(Ensembl_TRS)
Transducin beta chain 2(Synonym) G protein subunit beta-2(Synonym)
ENSBTAP00000008508(Ensembl_PRO) GBB2(Synonym)
A5D7A9(AltAccession) 281202(GeneID)
163111(GI) 146186921(GI)
160332367(GI) 148225064(GI)
NM_001097561(refSeq) 163785(GI)
121009(GI) GBB2_BOVIN(UniProtKB-ID)
ENSBTAG00000006495(Ensembl) NP_001091030(refSeq)
AAI40490(EMBL-CDS) AAA30552(EMBL-CDS)
163113(GI) AAA30553(EMBL-CDS)
M16539(EMBL) AAA62717(EMBL-CDS)
BC140489(EMBL)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-2 (PTHR19850:SF27)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Wnt signaling pathway
   G protein, beta subunit
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
GABA-B receptor II signaling
   G protein, beta subunit
Histamine H1 receptor mediated signaling pathway
   G-Protein
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Dopamine receptor mediated signaling pathway
   G protein, beta subunit
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein-activated inward rectifying potassium channel
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Endogenous cannabinoid signaling
   G protein, beta subunit
Beta1 adrenergic receptor signaling pathway
   G-Protein
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   G protein, beta subunit
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   G protein, beta subunit
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein beta subunit
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: GTPase activity, signaling receptor complex adaptor activity
GO BP Complete: G protein-coupled receptor signaling pathway, regulation of potassium ion transmembrane transport
GO CC Complete: heterotrimeric G-protein complex, perinuclear region of cytoplasm, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Chaperonin-mediated protein folding, Activation of G protein gated Potassium channels, G-protein activation, G beta:gamma signalling through CDC42, Platelet activation, signaling and aggregation, Signal Transduction, Metabolism, Hemostasis, ADP signalling through P2Y purinoceptor 12, G beta:gamma signalling through PI3Kgamma, Activation of GABAB receptors, G alpha (i) signalling events, ADP signalling through P2Y purinoceptor 1, Adrenaline,noradrenaline inhibits insulin secretion, G protein gated Potassium channels, Signal amplification, Ca2+ pathway, Integration of energy metabolism, GPCR downstream signalling, Presynaptic function of Kainate receptors, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, Extra-nuclear estrogen signaling, Opioid Signalling, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Vasopressin regulates renal water homeostasis via Aquaporins, G alpha (s) signalling events, G alpha (z) signalling events, Signaling by WNT, Activation of kainate receptors upon glutamate binding, G alpha (12/13) signalling events, Beta-catenin independent WNT signaling, Inwardly rectifying K+ channels, Aquaporin-mediated transport, Platelet homeostasis, Signaling by Nuclear Receptors, Thrombin signalling through proteinase activated receptors (PARs), Potassium Channels, Metabolism of proteins, Prostacyclin signalling through prostacyclin receptor, Glucagon-type ligand receptors, Transport of small molecules, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Thromboxane signalling through TP receptor, Regulation of insulin secretion, Signaling by GPCR, ESR-mediated signaling, GABA B receptor activation, Transmission across Chemical Synapses, GABA receptor activation, Neuronal System, G beta:gamma signalling through BTK, Neurotransmitter receptors and postsynaptic signal transmission, Protein folding, G alpha (q) signalling events, Class B/2 (Secretin family receptors), GPCR ligand binding, G-protein beta:gamma signalling, G beta:gamma signalling through PLC beta

Orthologs