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comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

GNG5

Organism:

Macaca mulatta

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Tree

Gene Name:

Guanine nucleotide-binding protein subunit gamma

Gene ID:

ENSMMUG00000022182.3

Protein ID:

F6XHP0

Persistent Id:

PTN000352072

Alternate Ids:

710548(GeneID)	JU471725(EMBL)
F6XHP0(Synonym)	AFI35659(EMBL-CDS)
NP_001252742(refSeq)	388453351(GI)
ENSMMUP00000029198(Ensembl_PRO)	F6XHP0_MACMU(UniProtKB-ID)
ENSMMUT00000031196(Ensembl_TRS)	ENSMMUG00000022182(Ensembl)
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PANTHER Classification

PANTHER Family:	GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT (PTHR13809)
PANTHER Subfamily:	GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-5-RELATED (PTHR13809:SF5)
PANTHER GO-slim Molecular Function:	protein binding
PANTHER GO-slim Biological Process:	G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane protein complex extrinsic component of membrane catalytic complex cytoplasmic side of plasma membrane
PANTHER protein class:	heterotrimeric G-protein

Pathway Categories:

Beta3 adrenergic receptor signaling pathway

G-Protein

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

G protein gamma subunit

Thyrotropin-releasing hormone receptor signaling pathway

G-Protein

Histamine H1 receptor mediated signaling pathway

G-Protein

Inflammation mediated by chemokine and cytokine signaling pathway

G protein, beta and gamma subunit

5HT1 type receptor mediated signaling pathway

G-protein

5HT4 type receptor mediated signaling pathway

G-protein

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

Gq-protein

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

G protein-activated inward rectifying potassium channel

Endogenous cannabinoid signaling

G-protein, gamma subunit

GABA-B receptor II signaling

Ggamma

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

G-protein, gamma subunit

Beta1 adrenergic receptor signaling pathway

G-Protein

Wnt signaling pathway

G-protein, gamma subunit

5HT2 type receptor mediated signaling pathway

G-protein

Enkephalin release

Gi-protein

Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction

G protein gamma subunit

Opioid proenkephalin pathway

G-protein

Enkephalin release

Gs-protein

Opioid prodynorphin pathway

G-protein

Beta2 adrenergic receptor signaling pathway

G-Protein

Histamine H2 receptor mediated signaling pathway

G-Protein

Opioid proopiomelanocortin pathway

G-protein

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

Gi-protein

Metabotropic glutamate receptor group III pathway

Gi-protein

Cortocotropin releasing factor receptor signaling pathway

G-Protein

Metabotropic glutamate receptor group II pathway

G-protein

Oxytocin receptor mediated signaling pathway

G-Protein

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	G-protein beta-subunit binding, PDZ domain binding
GO BP Complete:	G protein-coupled receptor signaling pathway, signal transduction, positive regulation of neural precursor cell proliferation, positive regulation of secondary heart field cardioblast proliferation
GO CC Complete:	heterotrimeric G-protein complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

-

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24826\|UniProtKB=A0A804HLA8	Homo sapiens	O
HUMAN\|HGNC=4408\|UniProtKB=P63218	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000050385.1\|UniProtKB=A0A2I3TXE7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000037601.1\|UniProtKB=A0A2I2ZC13	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=3782541\|UniProtKB=A0A3B2WD42	Mus musculus	O
MOUSE\|MGI=MGI=109164\|UniProtKB=Q80SZ7	Mus musculus	LDO
RAT\|RGD=11463329\|UniProtKB=F2Z3T8	Rattus norvegicus	LDO
RAT\|RGD=11417578\|UniProtKB=A0A8L2QRU2	Rattus norvegicus	O
RAT\|RGD=620807\|UniProtKB=P63219	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000049237.1\|UniProtKB=A0A3Q1N4Z3	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000008122\|UniProtKB=P63217	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000053185.1\|UniProtKB=A0A287B6W0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000048494.1\|UniProtKB=A0A9L0SLU1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000033315.3\|UniProtKB=A0A2I2U279	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000034799.2\|UniProtKB=A0A2I2U0C5	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000038836.3\|UniProtKB=A0A2I2V4I8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027377.1\|UniProtKB=A0A8I3PWP4	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845015057.1\|UniProtKB=A0A8I3RYN2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000048242.1\|UniProtKB=A0A5F8GVM4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000021004.2\|UniProtKB=F7ERP8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020952.1\|UniProtKB=R4GKD1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005743.2\|UniProtKB=H9GAI5	Anolis carolinensis	LDO
XENLA\|Gene=gng5.L\|UniProtKB=Q6GNC0	Xenopus laevis	O
XENLA\|Gene=gng5.S\|UniProtKB=Q6DKM2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-963560\|UniProtKB=Q0VFC4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012039.2\|UniProtKB=H2M989	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024599.1\|UniProtKB=A0A3B3I1D7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-8332\|UniProtKB=X1WBG0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-121214-209\|UniProtKB=R4GE45	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000024321.1\|UniProtKB=A0A3B3ICQ5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027348.1\|UniProtKB=A0A3B3HUT6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-9966\|UniProtKB=Q6TH03	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010068.1\|UniProtKB=W5MVA3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000024996.1\|UniProtKB=H2XXW5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020287.1\|UniProtKB=H2XQR3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018384.1\|UniProtKB=H2XP47	Ciona intestinalis	O
BRAFL\|Gene=LOC118418899\|UniProtKB=A0A9J7LEW6	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00001681\|UniProtKB=P54406	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00023553\|UniProtKB=Q4VT26	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00092573\|UniProtKB=A0A454XKS2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00089786\|UniProtKB=A0A454XM40	Pristionchus pacificus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_44980\|UniProtKB=E9G283	Daphnia pulex	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216887\|UniProtKB=A7SSR6	Nematostella vectensis	O