PANTHER Gene Information   
Gene Symbol(s): Pka-C1
Organism: Drosophila melanogaster
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: cAMP-dependent protein kinase catalytic subunit 1
Gene ID: FBgn0000273
Protein ID: P12370
Persistent Id: PTN000682646
Alternate Ids:
NP_476977(refSeq) Protein kinase DC0 {ECO:0000303|PubMed:3215511}(Synonym)
KAPC1_DROME(UniProtKB-ID) Q9VL99(AltAccession)
FBgn0000273(FlyBase) 34284(GeneID)
FBpp0089382(Ensembl_PRO) 17136902(GI)
FBtr0079851(Ensembl_TRS) Pka-C1(Symbol)
AAA28412(EMBL-CDS) AE014134(EMBL)
2.7.11.11 {ECO:0000305|PubMed:29473541}(EC) FBgn0000273(Ensembl)
Show All

PANTHER Classification
PANTHER Family: CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE (PTHR24353)
PANTHER Subfamily: CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1 (PTHR24353:SF153)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: serine/threonine protein kinase complex
intracellular protein-containing complex
nucleus
cytosol
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Metabotropic glutamate receptor group I pathway
   Protein kinase A
Metabotropic glutamate receptor group II pathway
   Protein kinase A
Inflammation mediated by chemokine and cytokine signaling pathway
   Protein kinase A
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Protein kinase A
Endothelin signaling pathway
   Protein kinase A
Enkephalin release
   Protein kinase A
Beta1 adrenergic receptor signaling pathway
   Protein kinase A
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   Protein kinase A
Dopamine receptor mediated signaling pathway
   Protein kinase A
5HT1 type receptor mediated signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group III pathway
   Protein kinase A
Histamine H2 receptor mediated signaling pathway
   Protein kinase A
Beta2 adrenergic receptor signaling pathway
   Protein kinase A
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, protein binding, cAMP-dependent protein kinase activity, protein serine/threonine kinase activity
GO BP Complete: negative regulation of mitochondrial DNA replication, imaginal disc-derived wing morphogenesis, oocyte microtubule cytoskeleton polarization, positive regulation of Atg1/ULK1 kinase complex assembly, protein phosphorylation, oocyte anterior/posterior axis specification, sprouting of injured axon, thermosensory behavior, positive regulation of hippo signaling, signal transduction, olfactory learning, regulation of apoptotic process, olfactory behavior, anterior/posterior pattern specification, imaginal disc, negative regulation of smoothened signaling pathway, regulation of bicoid mRNA localization, rhythmic behavior, negative regulation of nucleocytoplasmic transport, cellular response to ethanol, regulation of pole plasm oskar mRNA localization, anesthesia-resistant memory, regulation of actin cytoskeleton organization, oogenesis, positive regulation of gene expression, regulation of circadian sleep/wake cycle, sleep, positive regulation of smoothened signaling pathway, modulation of chemical synaptic transmission, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, cAMP-mediated signaling
GO CC Complete: nucleus, dendrite, mitochondrial matrix, cell body, cytosol, neuronal cell body, neuron projection, plasma membrane, cAMP-dependent protein kinase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: VEGFA-VEGFR2 Pathway, Signaling by VEGF, Ion homeostasis, G-protein mediated events, Signal Transduction, Signaling by Hedgehog, Signaling by Receptor Tyrosine Kinases, Assembly of the CI containing complexes, PLC beta mediated events, CaM pathway, Muscle contraction, Ubiquitination and proteolysis of phosphorylated CI, Ca-dependent events, Hemostasis, C-type lectin receptors (CLRs), Activation of NMDA receptors and postsynaptic events, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, Innate Immune System, Glucagon signaling in metabolic regulation, GLI3 is processed to GLI3R by the proteasome, Post NMDA receptor activation events, Hedgehog 'off' state, G alpha (s) signalling events, DAG and IP3 signaling, CREB1 phosphorylation through the activation of Adenylate Cyclase, G alpha (i) signalling events, Immune System, Metabolism of proteins, Intracellular signaling by second messengers, Hedgehog pathway, Opioid Signalling, Phosphorylation of CI, Integration of energy metabolism, GPCR downstream signalling, Aquaporin-mediated transport, Drosophila signaling pathways, PKA activation in glucagon signalling, Plasma lipoprotein assembly, remodeling, and clearance, Mitochondrial protein degradation, Factors involved in megakaryocyte development and platelet production, Cardiac conduction, PKA-mediated phosphorylation of CREB, PKA activation, Metabolism, Calmodulin induced events, Vasopressin regulates renal water homeostasis via Aquaporins, Regulation of insulin secretion, Rap1 signalling, HDL assembly, Adaptive Immune System, N-HH ligand not bound to PTC receptor complex, Plasma lipoprotein assembly, Signaling by GPCR, Neuronal System, CD209 (DC-SIGN) signaling, DARPP-32 events, Neurotransmitter receptors and postsynaptic signal transmission, Transmission across Chemical Synapses, GPER1 signaling, Transport of small molecules

Orthologs