PANTHER Gene Information   
Gene Symbol(s): Pik3r3
Organism: Rattus norvegicus
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: Phosphatidylinositol 3-kinase regulatory subunit gamma
Gene ID: 621042
Protein ID: Q63789
Persistent Id: PTN000016433
Alternate Ids:
Pik3r3(Symbol) BAA10927(EMBL-CDS)
621042(RGD) P55G(Synonym)
NP_071549(refSeq) 60664(GeneID)
11559994(GI) P55G_RAT(UniProtKB-ID)
D64047(EMBL)
Show All

PANTHER Classification
PANTHER Family: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)
PANTHER Subfamily: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA (PTHR10155:SF2)  
PANTHER GO-slim Molecular Function: kinase regulator activity
PANTHER GO-slim Biological Process: phosphatidylinositol phosphate biosynthetic process
insulin receptor signaling pathway
PANTHER GO-slim Cellular Component: phosphatidylinositol 3-kinase complex
PANTHER protein class: kinase modulator
Pathway Categories: VEGF signaling pathway
   Phosphatidylinositol 3-kinase
PI3 kinase pathway
   p85
T cell activation
   Phosphatidylinositol 3-kinase
Hypoxia response via HIF activation
   Phosphatidylinositol 3-kinase
Insulin/IGF pathway-protein kinase B signaling cascade
   Phosphatidylinositol 3-kinase
Angiogenesis
   Phosphatidylinositol 3-kinase
Integrin signalling pathway
   Phosphatidylinositol 3-kinase
Axon guidance mediated by netrin
   Phosphatidylinositol 3-kinase
Endothelin signaling pathway
   Phosphatidylinositol 3-kinase
PDGF signaling pathway
   Phosphatidylinositol 3-kinase
p53 pathway feedback loops 2
   Phosphatidylinositol 3-kinase
p53 pathway
   Phosphatidylinositol 3-kinase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: phosphotyrosine residue binding, 1-phosphatidylinositol-3-kinase regulator activity
GO BP Complete: phosphatidylinositol 3-kinase/protein kinase B signal transduction, insulin receptor signaling pathway, positive regulation of gene expression, positive regulation of protein phosphorylation, cell migration involved in sprouting angiogenesis
GO CC Complete: phosphatidylinositol 3-kinase complex, class IA, phosphatidylinositol 3-kinase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Phospholipid metabolism, Signaling by GPCR, Signaling by SCF-KIT, Hemostasis, ESR-mediated signaling, Extra-nuclear estrogen signaling, Interleukin receptor SHC signaling, PIP3 activates AKT signaling, RHO GTPase cycle, CD28 dependent PI3K/Akt signaling, Costimulation by the CD28 family, Interleukin-3, Interleukin-5 and GM-CSF signaling, Signaling by Interleukins, CD28 co-stimulation, Signaling by Nuclear Receptors, RAC1 GTPase cycle, Platelet activation, signaling and aggregation, RAC2 GTPase cycle, Signaling by Receptor Tyrosine Kinases, G alpha (q) signalling events, Developmental Biology, Interleukin-7 signaling, GPVI-mediated activation cascade, Nervous system development, Signaling by Rho GTPases, Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Synthesis of PIPs at the plasma membrane, Interleukin-2 family signaling, Axon guidance, Metabolism, RET signaling, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Regulation of signaling by CBL, Metabolism of lipids, GPCR downstream signalling, Negative regulation of the PI3K/AKT network, Immune System, Intracellular signaling by second messengers, Adaptive Immune System, PI Metabolism, Cytokine Signaling in Immune system

Orthologs