PANTHER Pathway  >   Angiotensin II-stimulated signaling through G proteins and beta-arrestin >   G protein-coupled receptor kinase 3

Pathway Component Details   
Name: G protein-coupled receptor kinase 3 (GRK3)
Definition: G protein-coupled receptor kinase 3 (GRK3) is a serine-threonine kinase that phosphorylates seven transmembrane receptors (7TMRs, also known as GPCRs) to promote their desensitization and internalization. It is structurally and functionally very similar to GRK2.
Category ID: P05941
Synonyms:
Upstream:
Downstream:
Number Families/Subfamilies: 2
Number of Associated Sequences: 7
GO Molecular Function: -
GO Biological Process: -
GO Cellular Component: -
PANTHER protein class: -
References: OMIM:109636 

Sequence Association
Panther Subfamily Associated Sequence Definition Confidence Code Evidence
PTHR24355:SF17 A0A5F8GHL2 G protein-coupled receptor kinase ISS PubMed:10852916  
  A0A5F8GHL2 G protein-coupled receptor kinase ISS PubMed:8288567  
  K7B2K4 G protein-coupled receptor kinase ISS PubMed:10852916  
  K7B2K4 G protein-coupled receptor kinase ISS PubMed:8288567  
  P26818 Beta-adrenergic receptor kinase 2 RCA PubMed:10852916  
  P26818 Beta-adrenergic receptor kinase 2 RCA PubMed:8288567  
  P35626 Beta-adrenergic receptor kinase 2 RCA PubMed:10852916  
  P35626 Beta-adrenergic receptor kinase 2 RCA PubMed:8288567  
  Q3UYH7 Beta-adrenergic receptor kinase 2 ISS PubMed:10852916  
  Q3UYH7 Beta-adrenergic receptor kinase 2 ISS PubMed:8288567  
PTHR24355:SF18 A0A2R8QPB8 G protein-coupled receptor kinase ISS PubMed:10852916  
  A0A2R8QPB8 G protein-coupled receptor kinase ISS PubMed:8288567