Pathway Component Details
| Name: | TGF beta-activated kinase 1 (TAK1) |
| Definition: | Transforming growth factor-b (TGF-b)-activated kinase is a member of the mitogen-activated protein kinase (MAPK) kinase kinase (MAPKKK) family of signal transduction kinases; it mediates the TGF-b signaling pathway. |
| Category ID: | P06037 |
| Synonyms: | |
| Upstream: |
TAK1 binding protein 2
(TAB2)
TAK1 binding protein (TAB1) |
| Downstream: |
mitogen-activated protein kinase kinase 6
(MKK6)
mitogen-activated protein kinase kinase 3 (MKK3) |
| Number Families/Subfamilies: | 1 |
| Number of Associated Sequences: | 8 |
| GO Molecular Function: |
-
|
| GO Biological Process: |
-
|
| GO Cellular Component: |
-
|
| PANTHER protein class: |
-
|
| References: | OMIM:602614 Medline:8533096 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR46716:SF1 | A0A5F8GJ40 | Mitogen-activated protein kinase kinase kinase 7 | ISS | PubMed:10683140 |
| A0A8I3N7L6 | Mitogen-activated protein kinase kinase kinase 7 | ISS | PubMed:10683140 | |
| A2VDU3 | Mitogen-activated protein kinase kinase kinase 7 | ISS | PubMed:10683140 | |
| H2RCY2 | Mitogen-activated protein kinase kinase kinase 7 | ISS | PubMed:10683140 | |
| O43318 | Mitogen-activated protein kinase kinase kinase 7 | RCA | PubMed:10683140 | |
| P0C8E4 | Mitogen-activated protein kinase kinase kinase 7 | ISS | PubMed:10683140 | |
| Q62073 | Mitogen-activated protein kinase kinase kinase 7 | RCA | PubMed:10683140 |
