PANTHER Gene Information

Gene Symbol(s):

PRKCA

Organism:

Anolis carolinensis

View Gene in Tree

Tree

Gene Name:

Protein kinase C

Gene ID:

ENSACAG00000000629.4

Protein ID:

A0A803SUC5

Persistent Id:

PTN001554083

Alternate Ids:

ENSACAT00000044630(Ensembl_TRS)	A0A803SUC5_ANOCA(UniProtKB-ID)
ENSACAG00000000629(Ensembl)	A0A803SUC5(Synonym)
ENSACAP00000026565(Ensembl_PRO)
Show All

PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	PROTEIN KINASE C ALPHA TYPE (PTHR24356:SF193)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

PKCs

Histamine H1 receptor mediated signaling pathway

Protein kinase C

Apoptosis signaling pathway

Protein kinase C

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

Protein kinase C

Angiotensin II-stimulated signaling through G proteins and beta-arrestin

protein kinase C

Wnt signaling pathway

Protein Kinase C

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

Protein kinase C

Oxytocin receptor mediated signaling pathway

Protein kinase C

PDGF signaling pathway

Protein kinase C

FGF signaling pathway

Protein kinase C

Thyrotropin-releasing hormone receptor signaling pathway

Protein kinase C

Angiogenesis

Protein kinase B

Gonadotropin-releasing hormone receptor pathway

PKCs(3)

Alpha adrenergic receptor signaling pathway

protein kinase C

CCKR signaling map

PKCalpha

Endothelin signaling pathway

protein kinase c

VEGF signaling pathway

Protein kinase C

Alzheimer disease-amyloid secretase pathway

Protein kinase C

EGF receptor signaling pathway

PKC

5HT2 type receptor mediated signaling pathway

Protein kinase C

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, zinc ion binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity, protein serine kinase activity, diacylglycerol-dependent serine/threonine kinase activity, enzyme binding, histone H3T6 kinase activity
GO BP Complete:	negative regulation of glial cell apoptotic process, regulation of platelet aggregation, positive regulation of angiotensin-activated signaling pathway, positive regulation of cell adhesion, post-translational protein modification, positive regulation of blood vessel endothelial cell migration, positive regulation of angiogenesis, positive regulation of mitotic cell cycle, desmosome assembly, chromatin remodeling, response to interleukin-1, positive regulation of endothelial cell proliferation, positive regulation of lipopolysaccharide-mediated signaling pathway, positive regulation of endothelial cell migration, intracellular signal transduction, positive regulation of cell migration
GO CC Complete:	cytoplasm, ciliary basal body, cytosol, endoplasmic reticulum, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9393\|UniProtKB=P17252	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009557.7\|UniProtKB=H2QDQ1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015929.3\|UniProtKB=G3RIN3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018378.4\|UniProtKB=H9EMT3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97595\|UniProtKB=P20444	Mus musculus	LDO
RAT\|RGD=3395\|UniProtKB=P05696	Rattus norvegicus	LDO
BOVIN\|Gene=PRKCA\|UniProtKB=P04409	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017268.5\|UniProtKB=F1RV14	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006771.4\|UniProtKB=F6W6Q5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012011.6\|UniProtKB=M3WG61	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027678.1\|UniProtKB=A0A8I3PUQ8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004147.4\|UniProtKB=F6RA79	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008060.3\|UniProtKB=F7CUS2	Ornithorhynchus anatinus	LDO
XENLA\|Gene=prkca.L\|UniProtKB=A0A8J1LPV0	Xenopus laevis	LDO
XENTR\|Gene=prkca\|UniProtKB=A0A8J1IZY1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008825.2\|UniProtKB=H2LY64	Oryzias latipes	O
DANRE\|Gene=si=ch73-374l24.1\|UniProtKB=A0A8M3AR84	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000013842.2\|UniProtKB=H2MFH9	Oryzias latipes	LDO
DANRE\|Gene=prkca\|UniProtKB=A0A8M9PM31	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-050208-100\|UniProtKB=A0A2R8QIY5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013639.1\|UniProtKB=W5N878	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008551.3\|UniProtKB=F6XQ16	Ciona intestinalis	O
CAEEL\|WormBase=WBGene00004033\|UniProtKB=P90980	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039957\|UniProtKB=A8XZI0	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00023650\|UniProtKB=A8WMH0	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00039960\|UniProtKB=A8XZH7	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG16150\|UniProtKB=A8XP04	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00110173\|UniProtKB=A0A2A6D1F3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0004784\|UniProtKB=P13677	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0003091\|UniProtKB=P05130	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP012252\|UniProtKB=A0A1S4H8S9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC032364\|UniProtKB=A0A139WLV0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_326383\|UniProtKB=E9H7K4	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020000\|UniProtKB=B7PWS6	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93932\|UniProtKB=A7RUL8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG20496\|UniProtKB=B3RQ26	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_31267\|UniProtKB=A9USR5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10752\|UniProtKB=A9V750	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21555\|UniProtKB=A9V1T6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34036\|UniProtKB=A9V9H6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_39232\|UniProtKB=A9VD19	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_20766\|UniProtKB=A9UXQ2	Monosiga brevicollis	O
YEAST\|SGD=S000000201\|UniProtKB=P24583	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR191C\|UniProtKB=Q75BT0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000201435\|UniProtKB=Q5ANK2	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F09746g\|UniProtKB=Q6C292	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00106\|UniProtKB=C8VQM0	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU06544\|UniProtKB=P87253	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_07073\|UniProtKB=Q0UME1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC17G8.14c\|UniProtKB=P36582	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPBC12D12.04c\|UniProtKB=P36583	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE01630\|UniProtKB=Q5KH12	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNC03300\|UniProtKB=Q5KKE3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_15023\|UniProtKB=A0A0D1DRE2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12641\|UniProtKB=E3KRH5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15370\|UniProtKB=F4NTP5	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19449\|UniProtKB=F4P170	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_125820\|UniProtKB=C4LVW8	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_097620\|UniProtKB=C4M933	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_188930\|UniProtKB=C4M2W0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_044470\|UniProtKB=B1N2G7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_042150\|UniProtKB=C4M4G9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_053040\|UniProtKB=C4M3C2	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_138540\|UniProtKB=A0A8U0WPI4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0288795\|UniProtKB=Q54IF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149347\|UniProtKB=F0ZDG7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0268620\|UniProtKB=P54644	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152431\|UniProtKB=F0ZLC3	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38849\|UniProtKB=F0ZVB0	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_30_0800\|UniProtKB=Q4Q7M5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.2290\|UniProtKB=Q383M7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.3.2690\|UniProtKB=Q582Y1	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_11364\|UniProtKB=E2RTY0	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_195270\|UniProtKB=A2FLX7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_324020\|UniProtKB=A2F4A4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_430560\|UniProtKB=A2E382	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_316050\|UniProtKB=A2FAW3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_447920\|UniProtKB=A2DS63	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_047250\|UniProtKB=A2FHJ2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_267830\|UniProtKB=A2DLD2	Trichomonas vaginalis	O
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O