PANTHER Gene Information

Gene Symbol(s):

PKH2

Organism:

Candida albicans

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Serine_threonine-protein kinase PKH2

Gene ID:

CAALFM_C112410CA

Protein ID:

Q5A3P6

Persistent Id:

PTN002390448

Alternate Ids:

PKH2{ECO:0000303\|PubMed:23911092}(Symbol)	PKB-activating kinase homolog 2 {ECO:0000250\|UniProtKB:Q12236}(Synonym)
XM_711200(refSeq)	AOW26859(EMBL-CDS)
2.7.11.1 {ECO:0000250\|UniProtKB:Q12236}(EC)	Q5A3V9(AltAccession)
CP017623(EMBL)	PKH2_CANAL(UniProtKB-ID)
1111954117(GI)	3642058(GeneID)
Show All

PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED (PTHR24356:SF163)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

CCKR signaling map

PDPK1

PI3 kinase pathway

Activated p110

Insulin/IGF pathway-protein kinase B signaling cascade

3-phosphoinositide-dependent protein kinase 1 and 2

Interleukin signaling pathway

3-phosphoinositide-dependent protein kinase 1 and 2

p53 pathway feedback loops 2

3-phosphoinositide-dependent protein kinase 1 and 2

Inflammation mediated by chemokine and cytokine signaling pathway

3-phosphoinositide-dependent protein kinase 1

Ras Pathway

3-phosphoinositide-dependent protein kinase

PDGF signaling pathway

3-phosphoinositide-dependent protein kinase 1 and 2

p53 pathway

3-phosphoinositide-dependent protein kinase 1 and 2

PI3 kinase pathway

3-phosphoinositide-dependent protein kinase 1, active

PI3 kinase pathway

3-phosphoinositide-dependent protein kinase 1

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, protein kinase activity, lipid binding, protein serine/threonine kinase activity
GO BP Complete:	filamentous growth, regulation of nuclear-transcribed mRNA poly(A) tail shortening, cell integrity MAPK cascade, positive regulation of cytoplasmic mRNA processing body assembly, protein phosphorylation, late endosome to vacuole transport via multivesicular body sorting pathway, intracellular signal transduction, sphingolipid metabolic process
GO CC Complete:	nucleus, cell cortex, eisosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=49897\|UniProtKB=Q6A1A2	Homo sapiens	O
HUMAN\|HGNC=8816\|UniProtKB=O15530	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007655.6\|UniProtKB=A0A2I3TN41	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010499.3\|UniProtKB=G3RXW1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000060539.1\|UniProtKB=F7B371	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000011459.4\|UniProtKB=H9ESX9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1338068\|UniProtKB=Q9Z2A0	Mus musculus	LDO
RAT\|RGD=620307\|UniProtKB=O55173	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000034436.4\|UniProtKB=F1MQJ7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000037719.3\|UniProtKB=A0A287AST6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000626.4\|UniProtKB=A0A9L0T0A3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001964.6\|UniProtKB=M3VXM6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003792.1\|UniProtKB=A0A8I3MQX7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016600.4\|UniProtKB=F6ZD74	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002330.3\|UniProtKB=A0A6I8ND89	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020316.1\|UniProtKB=A0A8V0Z6Y0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003492.4\|UniProtKB=H9G7Q7	Anolis carolinensis	LDO
XENLA\|Gene=pdpk1.L\|UniProtKB=A0A8J0PX21	Xenopus laevis	O
XENLA\|Gene=pdpk1.S\|UniProtKB=A0A1L8EQJ5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-991549\|UniProtKB=A0A6I8QZN8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007757.2\|UniProtKB=H2LUD8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-061013-109\|UniProtKB=Q08BG3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1820\|UniProtKB=Q6NZV1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003794.1\|UniProtKB=W5M823	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008253.3\|UniProtKB=F6QZH0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000007074.3\|UniProtKB=F6WVT9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428892\|UniProtKB=A0A9J7M6H1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581490\|UniProtKB=A0A7M7REI2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003965\|UniProtKB=Q9Y1J3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08059\|UniProtKB=A8X5P7	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00021022\|UniProtKB=Q9UA62	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG15660\|UniProtKB=A8XMH2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090219\|UniProtKB=A0A2A6BQN2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0020386\|UniProtKB=Q9W0V1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001471\|UniProtKB=A0A1S4GC66	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002973\|UniProtKB=D6WGV3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_299641\|UniProtKB=E9H687	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021115\|UniProtKB=B7Q978	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG63303\|UniProtKB=T1FXD8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG189040\|UniProtKB=T1FQL0	helobdella robusta	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g84740\|UniProtKB=A7RKQ3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG31577\|UniProtKB=B3S9G1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_12495\|UniProtKB=A9VCG3	Monosiga brevicollis	LDO
YEAST\|SGD=S000002874\|UniProtKB=Q03306	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR377C\|UniProtKB=Q753D9	Eremothecium gossypii	O
YEAST\|SGD=S000002898\|UniProtKB=Q03407	Saccharomyces cerevisiae	O
YEAST\|SGD=S000005460\|UniProtKB=Q12236	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR335C\|UniProtKB=Q753H7	Eremothecium gossypii	LDO
YARLI\|EnsemblGenome=YALI0_B05566g\|UniProtKB=Q6CFM7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03110\|UniProtKB=Q5B8M0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G12670\|UniProtKB=Q4WYD7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03571\|UniProtKB=Q1K4T2	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_13528\|UniProtKB=A7F7E8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06367\|UniProtKB=Q0UPE7	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC1778.10c\|UniProtKB=Q9Y7J6	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_05290\|UniProtKB=B6K3A0	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPCC576.15c\|UniProtKB=Q12701	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02468\|UniProtKB=B6K2J7	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC05250\|UniProtKB=Q5KJV3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05022\|UniProtKB=A0A0D1DX97	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04828\|UniProtKB=E3K315	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_18429\|UniProtKB=F4NVI4	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_095940\|UniProtKB=C4M3E9	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0284489\|UniProtKB=Q54PK9	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_36122\|UniProtKB=F0ZQF0	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0281471\|UniProtKB=Q54TW2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_56680\|UniProtKB=F0ZSM2	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_30_1000\|UniProtKB=Q4Q7K3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.6.2450\|UniProtKB=Q584R1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_31_1530\|UniProtKB=Q4Q6A9	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_15_1550\|UniProtKB=Q4QF23	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.211.2260\|UniProtKB=Q38DT1	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb09.160.3480\|UniProtKB=Q38F57	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_240510\|UniProtKB=A2EJ98	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_366130\|UniProtKB=A2DHQ7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_179780\|UniProtKB=A2F460	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_035920\|UniProtKB=A2DAR5	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1121900\|UniProtKB=Q8IIE7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00012278001\|UniProtKB=A0D109	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00035808001\|UniProtKB=A0C7B1	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00026239001\|UniProtKB=A0EF25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015687001\|UniProtKB=A0DCP1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026762001\|UniProtKB=A0EGJ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028949001\|UniProtKB=A0BH97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017845001\|UniProtKB=A0DKE9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013901001\|UniProtKB=A0D604	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036680001\|UniProtKB=A0CAT2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011716001\|UniProtKB=A0CZC6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022570001\|UniProtKB=A0E281	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024390001\|UniProtKB=A0E8P4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023731001\|UniProtKB=A0E6T6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011455001\|UniProtKB=A0CYI8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039825001\|UniProtKB=A0DXI4	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_15285\|UniProtKB=B8LDQ0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3H2Y5_PHYRM\|UniProtKB=H3H2Y5	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G7D1_PHYRM\|UniProtKB=H3G7D1	Phytophthora ramorum	O
PHYRM\|Gene=H3H2Y3_PHYRM\|UniProtKB=H3H2Y3	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GXW8_PHYRM\|UniProtKB=H3GXW8	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_11g467568v5\|UniProtKB=A0A2K3D7A2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00226660\|UniProtKB=W1NLJ0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_182G00450\|UniProtKB=A0A0K9PQW0	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_34G00970\|UniProtKB=A0A0K9P985	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g02780\|UniProtKB=A0A804HYM1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g28400\|UniProtKB=A0A804J9I8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_001110mg\|UniProtKB=K3XGT9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G372200\|UniProtKB=C5XRA6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb146330\|UniProtKB=C0P347	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0872800\|UniProtKB=A0A8J8XIM6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g56460v3\|UniProtKB=I1HTV2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0298800\|UniProtKB=F2DGV7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G376500\|UniProtKB=A0A3B6GYV5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G415800\|UniProtKB=A0A077RXS1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G383400\|UniProtKB=A0A3B6ER47	Triticum aestivum	LDO
NELNU\|Gene=LOC104612532\|UniProtKB=A0A1U8BAE0	Nelumbo nucifera	O
NELNU\|Gene=LOC104587314\|UniProtKB=A0A1U7Z834	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803688\|UniProtKB=A0A9R0KBY1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0329251\|UniProtKB=A0A251U4J0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0540521\|UniProtKB=A0A251T2F0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800397890\|UniProtKB=A0A9R1UVU2	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004635mg\|UniProtKB=A0A022RGQ0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a025938mg\|UniProtKB=A0A022PZT2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_08570\|UniProtKB=A0A2G2ZWX3	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400016913\|UniProtKB=M1BEU9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g071750.3\|UniProtKB=A0A3Q7FJB6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107785176\|UniProtKB=A0A1S3ZBS2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107817187\|UniProtKB=A0A1S4CBD3	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_29645\|UniProtKB=A0A1U8EX33	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG402027355\|UniProtKB=M1CM20	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107772058\|UniProtKB=A0A1S3Y4E2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107771346\|UniProtKB=A0A1S3Y2H4	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_13s0074g00100\|UniProtKB=F6I5U0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J01029\|UniProtKB=A0A059ADR3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C09P72250.1\|UniProtKB=A0A078I476	Brassica napus	O
BRACM\|EnsemblGenome=Bra009447\|UniProtKB=M4CZ00	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00000385001\|UniProtKB=A0A078F6C3	Brassica napus	O
BRACM\|EnsemblGenome=Bra029850\|UniProtKB=M4EM30	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00072920001\|UniProtKB=A0A078HVH8	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00072820001\|UniProtKB=A0A078JLF5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra034125\|UniProtKB=M4EZ82	Brassica campestris	LDO
ARATH\|TAIR=locus=2184357\|UniProtKB=Q9XF67	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2075740\|UniProtKB=Q4V3C8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107904178\|UniProtKB=A0A1U8J6I8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904334\|UniProtKB=A0A1U8J737	Gossypium hirsutum	O
GOSHI\|Gene=LOC107922041\|UniProtKB=A0A1U8KY46	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107960316\|UniProtKB=A0A1U8PPG4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_043455\|UniProtKB=A0A061FPC8	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g010859mg\|UniProtKB=A0A067EJG1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_010G232800v3\|UniProtKB=A0A2K1YZ23	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G028800v3\|UniProtKB=A0A2K1ZAQ8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_07G093000\|UniProtKB=A0A2C9VJV6	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_10G054000\|UniProtKB=A0A2C9V3M1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0008410\|UniProtKB=B9T6S2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G200600\|UniProtKB=I1LCP7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G190000\|UniProtKB=I1NHQ3	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g090917\|UniProtKB=A0A072VPR7	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_04280\|UniProtKB=A0A2I4HBU3	Juglans regia	O
JUGRE\|EnsemblGenome=Jr05_03610\|UniProtKB=A0A2I4EM46	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G616380\|UniProtKB=A0A0A0KRH7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G204000\|UniProtKB=A0A251QIQ5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_168798\|UniProtKB=D8R7N6	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_164063\|UniProtKB=D8QMJ5	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c26_8560\|UniProtKB=G9F9N7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0015s0182\|UniProtKB=A0A2R6XH34	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000940100\|UniProtKB=A0A1Y1HTF3	Klebsormidium nitens	LDO
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O