PANTHER Gene Information   
Gene Symbol(s): pdpk1
Organism: Xenopus tropicalis
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Gene Name: 3-phosphoinositide-dependent protein kinase 1
Gene ID: XB-GENE-991549
Protein ID: A0A6I8QZN8
Persistent Id: PTN008614830
Alternate Ids:
XM_002938414(refSeq) A0A6I8QZN8_XENTR(UniProtKB-ID)
ENSXETP00000077745(Ensembl_PRO) 1043410078(GI)
ENSXETT00000080394(Ensembl_TRS) 779524(GeneID)
ENSXETG00000004025(Ensembl) A0A6I8QZN8(Synonym)
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PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED (PTHR24356:SF163)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: CCKR signaling map
   PDPK1
PI3 kinase pathway
   Activated p110
Insulin/IGF pathway-protein kinase B signaling cascade
   3-phosphoinositide-dependent protein kinase 1 and 2
Interleukin signaling pathway
   3-phosphoinositide-dependent protein kinase 1 and 2
p53 pathway feedback loops 2
   3-phosphoinositide-dependent protein kinase 1 and 2
Inflammation mediated by chemokine and cytokine signaling pathway
   3-phosphoinositide-dependent protein kinase 1
Ras Pathway
   3-phosphoinositide-dependent protein kinase
PDGF signaling pathway
   3-phosphoinositide-dependent protein kinase 1 and 2
p53 pathway
   3-phosphoinositide-dependent protein kinase 1 and 2
PI3 kinase pathway
   3-phosphoinositide-dependent protein kinase 1, active
PI3 kinase pathway
   3-phosphoinositide-dependent protein kinase 1

GO MF Complete: histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, protein kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H2AS121 kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, histone H3T6 kinase activity
GO BP Complete: intracellular signal transduction
GO CC Complete: -
Reactome Pathways: Downstream TCR signaling, Signal Transduction, Innate Immune System, TCR signaling, Signaling by Rho GTPases, Signaling by VEGF, Activation of AKT2, Costimulation by the CD28 family, Role of LAT2/NTAL/LAB on calcium mobilization, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Signaling by Rho GTPases, Miro GTPases and RHOBTB3, CD28 dependent PI3K/Akt signaling, RHO GTPases activate PKNs, CD28 co-stimulation, Adaptive Immune System, GPVI-mediated activation cascade, Integrin signaling, RHO GTPase Effectors, VEGFA-VEGFR2 Pathway, Fc epsilon receptor (FCERI) signaling, Signaling by Insulin receptor, Insulin receptor signalling cascade, Intracellular signaling by second messengers, Hemostasis, Immune System, VEGFR2 mediated cell proliferation, PI3K Cascade, IRS-related events triggered by IGF1R, VEGFR2 mediated vascular permeability, PIP3 activates AKT signaling, Platelet Aggregation (Plug Formation), IGF1R signaling cascade, Signaling by Receptor Tyrosine Kinases, Platelet activation, signaling and aggregation, IRS-mediated signalling