PANTHER Gene Information

Gene Symbol(s):

Tb09.160.3480

Organism:

Trypanosoma brucei

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Tree

Gene Name:

Protein kinase, putative

Gene ID:

Tb09.160.3480

Protein ID:

Q38F57

Persistent Id:

PTN002390463

Alternate Ids:

XP_803794(refSeq)	3660315(GeneID)
EAN76563(EMBL-CDS)	CM000207(EMBL)
Q38F57_TRYB2(UniProtKB-ID)	71744526(GI)
Q38F57(Synonym)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED (PTHR24356:SF163)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

CCKR signaling map

PDPK1

PI3 kinase pathway

Activated p110

Insulin/IGF pathway-protein kinase B signaling cascade

3-phosphoinositide-dependent protein kinase 1 and 2

Interleukin signaling pathway

3-phosphoinositide-dependent protein kinase 1 and 2

p53 pathway feedback loops 2

3-phosphoinositide-dependent protein kinase 1 and 2

Inflammation mediated by chemokine and cytokine signaling pathway

3-phosphoinositide-dependent protein kinase 1

Ras Pathway

3-phosphoinositide-dependent protein kinase

PDGF signaling pathway

3-phosphoinositide-dependent protein kinase 1 and 2

p53 pathway

3-phosphoinositide-dependent protein kinase 1 and 2

PI3 kinase pathway

3-phosphoinositide-dependent protein kinase 1, active

PI3 kinase pathway

3-phosphoinositide-dependent protein kinase 1

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein serine/threonine kinase activity
GO BP Complete:	intracellular signal transduction
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=49897\|UniProtKB=Q6A1A2	Homo sapiens	O
HUMAN\|HGNC=8816\|UniProtKB=O15530	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007655.6\|UniProtKB=A0A2I3TN41	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010499.3\|UniProtKB=G3RXW1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000060539.1\|UniProtKB=F7B371	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000011459.4\|UniProtKB=H9ESX9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1338068\|UniProtKB=Q9Z2A0	Mus musculus	LDO
RAT\|RGD=620307\|UniProtKB=O55173	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000034436.4\|UniProtKB=F1MQJ7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000037719.3\|UniProtKB=A0A287AST6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000626.4\|UniProtKB=A0A9L0T0A3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001964.6\|UniProtKB=M3VXM6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003792.1\|UniProtKB=A0A8I3MQX7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016600.4\|UniProtKB=F6ZD74	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002330.3\|UniProtKB=A0A6I8ND89	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020316.1\|UniProtKB=A0A8V0Z6Y0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003492.4\|UniProtKB=H9G7Q7	Anolis carolinensis	LDO
XENLA\|Gene=pdpk1.L\|UniProtKB=A0A8J0PX21	Xenopus laevis	O
XENLA\|Gene=pdpk1.S\|UniProtKB=A0A1L8EQJ5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-991549\|UniProtKB=A0A6I8QZN8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007757.2\|UniProtKB=H2LUD8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-061013-109\|UniProtKB=Q08BG3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1820\|UniProtKB=Q6NZV1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003794.1\|UniProtKB=W5M823	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008253.3\|UniProtKB=F6QZH0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000007074.3\|UniProtKB=F6WVT9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428892\|UniProtKB=A0A9J7M6H1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581490\|UniProtKB=A0A7M7REI2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003965\|UniProtKB=Q9Y1J3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08059\|UniProtKB=A8X5P7	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00021022\|UniProtKB=Q9UA62	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG15660\|UniProtKB=A8XMH2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090219\|UniProtKB=A0A2A6BQN2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0020386\|UniProtKB=Q9W0V1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001471\|UniProtKB=A0A1S4GC66	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002973\|UniProtKB=D6WGV3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_299641\|UniProtKB=E9H687	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021115\|UniProtKB=B7Q978	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG63303\|UniProtKB=T1FXD8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG189040\|UniProtKB=T1FQL0	helobdella robusta	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g84740\|UniProtKB=A7RKQ3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG31577\|UniProtKB=B3S9G1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_12495\|UniProtKB=A9VCG3	Monosiga brevicollis	LDO
YEAST\|SGD=S000002874\|UniProtKB=Q03306	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR377C\|UniProtKB=Q753D9	Eremothecium gossypii	O
YEAST\|SGD=S000002898\|UniProtKB=Q03407	Saccharomyces cerevisiae	O
YEAST\|SGD=S000005460\|UniProtKB=Q12236	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR335C\|UniProtKB=Q753H7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000179865\|UniProtKB=A0A1D8PPB9	Candida albicans	O
CANAL\|Gene_OrderedLocusName=CAALFM_C112410CA\|UniProtKB=Q5A3P6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B05566g\|UniProtKB=Q6CFM7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03110\|UniProtKB=Q5B8M0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G12670\|UniProtKB=Q4WYD7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03571\|UniProtKB=Q1K4T2	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_13528\|UniProtKB=A7F7E8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06367\|UniProtKB=Q0UPE7	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC1778.10c\|UniProtKB=Q9Y7J6	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_05290\|UniProtKB=B6K3A0	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPCC576.15c\|UniProtKB=Q12701	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02468\|UniProtKB=B6K2J7	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC05250\|UniProtKB=Q5KJV3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05022\|UniProtKB=A0A0D1DX97	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04828\|UniProtKB=E3K315	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_18429\|UniProtKB=F4NVI4	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_095940\|UniProtKB=C4M3E9	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0284489\|UniProtKB=Q54PK9	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_36122\|UniProtKB=F0ZQF0	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0281471\|UniProtKB=Q54TW2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_56680\|UniProtKB=F0ZSM2	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_31_1530\|UniProtKB=Q4Q6A9	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_15_1550\|UniProtKB=Q4QF23	Leishmania major	LDO
TRIV3\|Gene_ORFName=TVAG_240510\|UniProtKB=A2EJ98	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_366130\|UniProtKB=A2DHQ7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_179780\|UniProtKB=A2F460	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_035920\|UniProtKB=A2DAR5	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1121900\|UniProtKB=Q8IIE7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00012278001\|UniProtKB=A0D109	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00035808001\|UniProtKB=A0C7B1	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00026239001\|UniProtKB=A0EF25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015687001\|UniProtKB=A0DCP1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026762001\|UniProtKB=A0EGJ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028949001\|UniProtKB=A0BH97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017845001\|UniProtKB=A0DKE9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013901001\|UniProtKB=A0D604	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036680001\|UniProtKB=A0CAT2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011716001\|UniProtKB=A0CZC6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022570001\|UniProtKB=A0E281	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024390001\|UniProtKB=A0E8P4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023731001\|UniProtKB=A0E6T6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011455001\|UniProtKB=A0CYI8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039825001\|UniProtKB=A0DXI4	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_15285\|UniProtKB=B8LDQ0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3H2Y5_PHYRM\|UniProtKB=H3H2Y5	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G7D1_PHYRM\|UniProtKB=H3G7D1	Phytophthora ramorum	O
PHYRM\|Gene=H3H2Y3_PHYRM\|UniProtKB=H3H2Y3	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GXW8_PHYRM\|UniProtKB=H3GXW8	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_11g467568v5\|UniProtKB=A0A2K3D7A2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00226660\|UniProtKB=W1NLJ0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_182G00450\|UniProtKB=A0A0K9PQW0	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_34G00970\|UniProtKB=A0A0K9P985	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g02780\|UniProtKB=A0A804HYM1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g28400\|UniProtKB=A0A804J9I8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_001110mg\|UniProtKB=K3XGT9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G372200\|UniProtKB=C5XRA6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb146330\|UniProtKB=C0P347	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0872800\|UniProtKB=A0A8J8XIM6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g56460v3\|UniProtKB=I1HTV2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0298800\|UniProtKB=F2DGV7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G376500\|UniProtKB=A0A3B6GYV5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G415800\|UniProtKB=A0A077RXS1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G383400\|UniProtKB=A0A3B6ER47	Triticum aestivum	LDO
NELNU\|Gene=LOC104612532\|UniProtKB=A0A1U8BAE0	Nelumbo nucifera	O
NELNU\|Gene=LOC104587314\|UniProtKB=A0A1U7Z834	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803688\|UniProtKB=A0A9R0KBY1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0329251\|UniProtKB=A0A251U4J0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0540521\|UniProtKB=A0A251T2F0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800397890\|UniProtKB=A0A9R1UVU2	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004635mg\|UniProtKB=A0A022RGQ0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a025938mg\|UniProtKB=A0A022PZT2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_08570\|UniProtKB=A0A2G2ZWX3	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400016913\|UniProtKB=M1BEU9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g071750.3\|UniProtKB=A0A3Q7FJB6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107785176\|UniProtKB=A0A1S3ZBS2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107817187\|UniProtKB=A0A1S4CBD3	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_29645\|UniProtKB=A0A1U8EX33	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG402027355\|UniProtKB=M1CM20	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107772058\|UniProtKB=A0A1S3Y4E2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107771346\|UniProtKB=A0A1S3Y2H4	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_13s0074g00100\|UniProtKB=F6I5U0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J01029\|UniProtKB=A0A059ADR3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C09P72250.1\|UniProtKB=A0A078I476	Brassica napus	O
BRACM\|EnsemblGenome=Bra009447\|UniProtKB=M4CZ00	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00000385001\|UniProtKB=A0A078F6C3	Brassica napus	O
BRACM\|EnsemblGenome=Bra029850\|UniProtKB=M4EM30	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00072920001\|UniProtKB=A0A078HVH8	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00072820001\|UniProtKB=A0A078JLF5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra034125\|UniProtKB=M4EZ82	Brassica campestris	LDO
ARATH\|TAIR=locus=2184357\|UniProtKB=Q9XF67	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2075740\|UniProtKB=Q4V3C8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107904178\|UniProtKB=A0A1U8J6I8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904334\|UniProtKB=A0A1U8J737	Gossypium hirsutum	O
GOSHI\|Gene=LOC107922041\|UniProtKB=A0A1U8KY46	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107960316\|UniProtKB=A0A1U8PPG4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_043455\|UniProtKB=A0A061FPC8	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g010859mg\|UniProtKB=A0A067EJG1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_010G232800v3\|UniProtKB=A0A2K1YZ23	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G028800v3\|UniProtKB=A0A2K1ZAQ8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_07G093000\|UniProtKB=A0A2C9VJV6	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_10G054000\|UniProtKB=A0A2C9V3M1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0008410\|UniProtKB=B9T6S2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G200600\|UniProtKB=I1LCP7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G190000\|UniProtKB=I1NHQ3	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g090917\|UniProtKB=A0A072VPR7	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_04280\|UniProtKB=A0A2I4HBU3	Juglans regia	O
JUGRE\|EnsemblGenome=Jr05_03610\|UniProtKB=A0A2I4EM46	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G616380\|UniProtKB=A0A0A0KRH7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G204000\|UniProtKB=A0A251QIQ5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_168798\|UniProtKB=D8R7N6	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_164063\|UniProtKB=D8QMJ5	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c26_8560\|UniProtKB=G9F9N7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0015s0182\|UniProtKB=A0A2R6XH34	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000940100\|UniProtKB=A0A1Y1HTF3	Klebsormidium nitens	LDO
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O