PANTHER Gene Information   
Gene Symbol(s): GNB4
Organism: Canis lupus familiaris
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Gene Name: G protein subunit beta 4
Gene ID: ENSCAFG00845016005.1
Protein ID: A0A8I3NPM9
Persistent Id: PTN000457555
Alternate Ids:
A0A8I3NPM9_CANLF(UniProtKB-ID) XM_545211(refSeq)
57110000(GI) ENSCAFP00845022529(Ensembl_PRO)
A0A8I3NPM9(Synonym) ENSCAFG00845016005(Ensembl)
ENSCAFT00845028625(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 (PTHR19850:SF28)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane protein complex
extrinsic component of membrane
cytoplasm
catalytic complex
cytoplasmic side of plasma membrane
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Wnt signaling pathway
   G protein, beta subunit
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
GABA-B receptor II signaling
   G protein, beta subunit
Histamine H1 receptor mediated signaling pathway
   G-Protein
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Dopamine receptor mediated signaling pathway
   G protein, beta subunit
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein-activated inward rectifying potassium channel
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   G protein, beta subunit
Endogenous cannabinoid signaling
   G protein, beta subunit
Beta1 adrenergic receptor signaling pathway
   G-Protein
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
   G protein, beta subunit
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein beta subunit
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: signaling receptor complex adaptor activity, protein-containing complex binding
GO BP Complete: G protein-coupled receptor signaling pathway
GO CC Complete: heterotrimeric G-protein complex, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Neuronal System, Inwardly rectifying K+ channels, G alpha (s) signalling events, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, G alpha (z) signalling events, GABA B receptor activation, GABA receptor activation, Class B/2 (Secretin family receptors), Signaling by GPCR, Transmission across Chemical Synapses, Neurotransmitter receptors and postsynaptic signal transmission, Chaperonin-mediated protein folding, GPCR ligand binding, Extra-nuclear estrogen signaling, Glucagon-type ligand receptors, Thromboxane signalling through TP receptor, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, Regulation of insulin secretion, G alpha (i) signalling events, Signal amplification, ADP signalling through P2Y purinoceptor 1, Transport of small molecules, Signal Transduction, Platelet homeostasis, Metabolism, G beta:gamma signalling through CDC42, G protein gated Potassium channels, Ca2+ pathway, Protein folding, G alpha (12/13) signalling events, Aquaporin-mediated transport, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Signaling by Nuclear Receptors, G alpha (q) signalling events, G beta:gamma signalling through PLC beta, Activation of G protein gated Potassium channels, Vasopressin regulates renal water homeostasis via Aquaporins, Integration of energy metabolism, Signaling by WNT, Presynaptic function of Kainate receptors, Opioid Signalling, Activation of kainate receptors upon glutamate binding, G-protein beta:gamma signalling, ESR-mediated signaling, Adrenaline,noradrenaline inhibits insulin secretion, Prostacyclin signalling through prostacyclin receptor, Metabolism of proteins, GPCR downstream signalling, Activation of GABAB receptors, G beta:gamma signalling through BTK, Platelet activation, signaling and aggregation, GPER1 signaling, Beta-catenin independent WNT signaling, Potassium Channels, Hemostasis, ADP signalling through P2Y purinoceptor 12, Thrombin signalling through proteinase activated receptors (PARs), G beta:gamma signalling through PI3Kgamma, G-protein activation

Orthologs