PANTHER Gene Information

Gene Symbol(s):

THRB

Organism:

Gallus gallus

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Gene Name:

Thyroid hormone receptor beta

Gene ID:

ENSGALG00010001557

Protein ID:

P68306

Persistent Id:

PTN000637896

Alternate Ids:

ENSGALP00015001191(Ensembl_PRO)	396431(GeneID)
THRB(Symbol)	C-ERBA-BETA(Synonym)
AAA49107(EMBL-CDS)	ENSGALT00010003607(Ensembl_TRS)
ENSGALG00010001557(Ensembl)	Z50188(EMBL)
XM_015281324(refSeq)	971379857(GI)
THB_CHICK(UniProtKB-ID)	P18112(AltAccession)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	THYROID HORMONE RECEPTOR BETA (PTHR24082:SF210)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway intracellular receptor signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	RNA polymerase II transcription regulator complex
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, protein binding, nuclear receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, thyroid hormone binding, sequence-specific double-stranded DNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, retinoic acid receptor signaling pathway, cell differentiation, thyroid hormone receptor signaling pathway, positive regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, RNA polymerase II transcription regulator complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RNA Polymerase II Transcription, Gene expression (Transcription), Post-translational protein modification, Metabolism of proteins, SUMO E3 ligases SUMOylate target proteins, SUMOylation of intracellular receptors, SUMOylation, Nuclear Receptor transcription pathway, Generic Transcription Pathway

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11799\|UniProtKB=P10828	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014697.6\|UniProtKB=H2R3K3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007268.3\|UniProtKB=G3S6W6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000067.4\|UniProtKB=F7G9B9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98743\|UniProtKB=P37242	Mus musculus	LDO
RAT\|RGD=3858\|UniProtKB=P18113	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017802.6\|UniProtKB=G3X7C1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036033.3\|UniProtKB=A0A286ZWA8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019007.4\|UniProtKB=F7E341	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022754.4\|UniProtKB=A0A2I2UAC2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019516.1\|UniProtKB=A0A8I3P5V7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014903.4\|UniProtKB=A0A5F8GH58	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012237.4\|UniProtKB=A0A6I8NFL6	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000011465.4\|UniProtKB=R4GD38	Anolis carolinensis	LDO
XENLA\|Gene=thrb-b\|UniProtKB=P18119	Xenopus laevis	O
XENLA\|Gene=thrb.S\|UniProtKB=A0A1L8FRG8	Xenopus laevis	O
XENLA\|Gene=thrb-a\|UniProtKB=P18117	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6070709\|UniProtKB=E7CYG4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008122.2\|UniProtKB=H2LVQ7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-268\|UniProtKB=Q9PVE4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006846.1\|UniProtKB=W5MIT5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021968.1\|UniProtKB=H2XNI0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405346\|UniProtKB=A0A9J7KIJ2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584535\|UniProtKB=A0A7M7N2J7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O