PANTHER Gene Information   
Gene Symbol(s): Thrb
Organism: Rattus norvegicus
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Gene Name: Thyroid hormone receptor beta
Gene ID: 3858
Protein ID: P18113
Persistent Id: PTN000637892
Alternate Ids:
M25071(EMBL) 303324989(GI)
THB_RAT(UniProtKB-ID) AAA60743(EMBL-CDS)
CHEMBL3917(ChEMBL) 3858(RGD)
Thrb(Symbol) Nuclear receptor subfamily 1 group A member 2(Synonym)
P37826(AltAccession)
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PANTHER Classification
PANTHER Family: NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily: THYROID HORMONE RECEPTOR BETA (PTHR24082:SF210)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
signaling receptor activity
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
cell differentiation
hormone-mediated signaling pathway
intracellular receptor signaling pathway
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: RNA polymerase II transcription regulator complex
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: chromatin DNA binding, zinc ion binding, identical protein binding, nuclear receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, double-stranded DNA binding, thyroid hormone binding, sequence-specific DNA binding, chromatin binding, sequence-specific double-stranded DNA binding, transcription coactivator binding, enzyme binding
GO BP Complete: positive regulation of cell population proliferation, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, sensory perception of sound, cellular response to thyroid hormone stimulus, retinoic acid receptor signaling pathway, negative regulation of DNA-templated transcription, type I pneumocyte differentiation, intracellular receptor signaling pathway, mRNA transcription by RNA polymerase II, female courtship behavior, regulation of heart contraction, regulation of DNA-templated transcription, embryonic organ development, thyroid hormone receptor signaling pathway, retinal cone cell development, negative regulation of female receptivity, positive regulation of thyroid hormone receptor signaling pathway, regulation of transcription by RNA polymerase II, animal organ morphogenesis, positive regulation of ossification, regulation of cholesterol metabolic process, retinal cone cell apoptotic process, cell differentiation, positive regulation of chondrocyte differentiation, regulation of lipid metabolic process, regulation of triglyceride metabolic process
GO CC Complete: nucleus, nuclear body, RNA polymerase II transcription regulator complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Nuclear Receptor transcription pathway, Generic Transcription Pathway, SUMO E3 ligases SUMOylate target proteins, SUMOylation of intracellular receptors, SUMOylation, Metabolism of proteins, Post-translational protein modification, Gene expression (Transcription), RNA Polymerase II Transcription

Orthologs