PANTHER Gene Information

Gene Symbol(s):

Organism:

Strongylocentrotus purpuratus

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Gene Name:

Thyroid hormone receptor beta

Gene ID:

LOC584535

Protein ID:

A0A7M7N2J7

Persistent Id:

PTN001941443

Alternate Ids:

XM_030973850(Ensembl_TRS)	LOC584535(Ensembl)
XP_030829710(Ensembl_PRO)	A0A7M7N2J7(Synonym)
A0A7M7N2J7_STRPU(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	THYROID HORMONE RECEPTOR BETA (PTHR24082:SF330)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway intracellular receptor signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, retinoic acid receptor signaling pathway, cell differentiation, regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9866\|UniProtKB=P13631	Homo sapiens	O
MACMU\|Ensembl=ENSMMUG00000022017.4\|UniProtKB=F7FAT5	Macaca mulatta	O
MOUSE\|MGI=MGI=97858\|UniProtKB=P18911	Mus musculus	O
RAT\|RGD=1583230\|UniProtKB=D3ZF61	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007592.5\|UniProtKB=Q08DD4	Bos taurus	O
FELCA\|Ensembl=ENSFCAG00000005870.6\|UniProtKB=A0A337SWD3	Felis catus	O
ORNAN\|Ensembl=ENSOANG00000012236.3\|UniProtKB=A0A6I8PHC3	Ornithorhynchus anatinus	O
DANRE\|ZFIN=ZDB-GENE-070314-1\|UniProtKB=A2T928	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-531\|UniProtKB=Q91392	Danio rerio	O
HUMAN\|HGNC=9865\|UniProtKB=P10826	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014698.6\|UniProtKB=A0A2I3T0W6	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000007367.4\|UniProtKB=A0A1D5QJY1	Macaca mulatta	O
MOUSE\|MGI=MGI=97857\|UniProtKB=P22605	Mus musculus	O
RAT\|RGD=1584366\|UniProtKB=D3ZFD9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011518.6\|UniProtKB=G3X6X1	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000016976.3\|UniProtKB=A0A9L0R765	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000010409.6\|UniProtKB=M3WD77	Felis catus	O
MONDO\|Ensembl=ENSMODG00000014926.4\|UniProtKB=F7FVH3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046457.1\|UniProtKB=A0A6I8P5Y0	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002438\|UniProtKB=P22448	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009257.3\|UniProtKB=A0A803T6U7	Anolis carolinensis	O
HUMAN\|HGNC=9864\|UniProtKB=P10276	Homo sapiens	O
MACMU\|Ensembl=ENSMMUG00000012486.4\|UniProtKB=I0FG13	Macaca mulatta	O
MOUSE\|MGI=MGI=97856\|UniProtKB=P11416	Mus musculus	O
RAT\|RGD=3534\|UniProtKB=A0A0G2JW78	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012500.6\|UniProtKB=F1MWQ3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017475.5\|UniProtKB=A0A480PNE7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000023358.4\|UniProtKB=A0A3Q2KZX5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000028515.4\|UniProtKB=A0A2I2USN5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845008607.1\|UniProtKB=A0A8I3MYI9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000013112.3\|UniProtKB=A0A5F8GD96	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000041579.1\|UniProtKB=A0A6I8N103	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00015025319\|UniProtKB=Q90966	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002413.4\|UniProtKB=G1KAS4	Anolis carolinensis	O
DANRE\|ZFIN=ZDB-GENE-980526-72\|UniProtKB=Q7ZTI3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-284\|UniProtKB=Q90271	Danio rerio	O
CIOIN\|Ensembl=ENSCING00000006945.3\|UniProtKB=F6VND6	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_116859\|UniProtKB=Q8MX80	Branchiostoma floridae	O
HUMAN\|HGNC=11796\|UniProtKB=P10827	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009112.4\|UniProtKB=H2QCV7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009661.3\|UniProtKB=A0A2I2ZI23	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002931.4\|UniProtKB=F7H1N5	Macaca mulatta	O
MOUSE\|MGI=MGI=98742\|UniProtKB=P63058	Mus musculus	O
RAT\|RGD=3857\|UniProtKB=P63059	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010745.4\|UniProtKB=A0A3Q1N8R7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000035969\|UniProtKB=O97716	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011120.4\|UniProtKB=F6ZL91	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845009925.1\|UniProtKB=A0A8I3NDL1	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000047374.1\|UniProtKB=A0A6I8PHB7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024621\|UniProtKB=P04625	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002898.4\|UniProtKB=G1KBE2	Anolis carolinensis	O
XENLA\|Gene=thra-b\|UniProtKB=P18115	Xenopus laevis	O
XENLA\|Gene=thra.S\|UniProtKB=A0A1L8EKN8	Xenopus laevis	O
XENLA\|Gene=thra.L\|UniProtKB=A0A8J0TQR7	Xenopus laevis	O
XENLA\|Gene=thra-a\|UniProtKB=P15204	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5966551\|UniProtKB=B3GR07	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016941.2\|UniProtKB=A0A3B3H792	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000012005.2\|UniProtKB=Q766D2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-263\|UniProtKB=Q98867	Danio rerio	O
DANRE\|Gene=thrab\|UniProtKB=A0A8M3B4P5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013012.1\|UniProtKB=W5N5X2	lepisosteus oculatus	O
HUMAN\|HGNC=11799\|UniProtKB=P10828	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014697.6\|UniProtKB=H2R3K3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007268.3\|UniProtKB=G3S6W6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000067.4\|UniProtKB=F7G9B9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98743\|UniProtKB=P37242	Mus musculus	LDO
RAT\|RGD=3858\|UniProtKB=P18113	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017802.6\|UniProtKB=G3X7C1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036033.3\|UniProtKB=A0A286ZWA8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019007.4\|UniProtKB=F7E341	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022754.4\|UniProtKB=A0A2I2UAC2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019516.1\|UniProtKB=A0A8I3P5V7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014903.4\|UniProtKB=A0A5F8GH58	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012237.4\|UniProtKB=A0A6I8NFL6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001557\|UniProtKB=P68306	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011465.4\|UniProtKB=R4GD38	Anolis carolinensis	LDO
XENLA\|Gene=thrb-b\|UniProtKB=P18119	Xenopus laevis	O
XENLA\|Gene=thrb.S\|UniProtKB=A0A1L8FRG8	Xenopus laevis	O
XENLA\|Gene=thrb-a\|UniProtKB=P18117	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6070709\|UniProtKB=E7CYG4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008122.2\|UniProtKB=H2LVQ7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-268\|UniProtKB=Q9PVE4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006846.1\|UniProtKB=W5MIT5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021968.1\|UniProtKB=H2XNI0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405346\|UniProtKB=A0A9J7KIJ2	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O