PANTHER Gene Information

Gene Symbol(s):

thraa

Organism:

Danio rerio

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Thyroid hormone receptor alpha-A

Gene ID:

ZDB-GENE-990415-263

Protein ID:

Q98867

Persistent Id:

PTN000637879

Alternate Ids:

U54796(EMBL)	XP_009297789(refSeq)
ZDB-GENE-990415-263(ZFIN)	30670(GeneID)
zTRalpha-A(Synonym)	thraa(Symbol)
6094469(GI)	AAH96778(EMBL-CDS)
THAA_DANRE(UniProtKB-ID)	Q4V9Q5(AltAccession)
Show All

PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	THYROID HORMONE RECEPTOR ALPHA (PTHR24082:SF42)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway intracellular receptor signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	RNA polymerase II transcription regulator complex
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, protein binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding
GO BP Complete:	positive regulation of sarcomere organization, neural crest cell development, regulation of DNA-templated transcription, thyroid hormone receptor signaling pathway, response to hormone, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, ventricular system development, heart development, retinoic acid receptor signaling pathway, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, cell differentiation
GO CC Complete:	nucleus, RNA polymerase II transcription regulator complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11796\|UniProtKB=P10827	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009112.4\|UniProtKB=H2QCV7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009661.3\|UniProtKB=A0A2I2ZI23	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002931.4\|UniProtKB=F7H1N5	Macaca mulatta	O
MOUSE\|MGI=MGI=98742\|UniProtKB=P63058	Mus musculus	O
RAT\|RGD=3857\|UniProtKB=P63059	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010745.4\|UniProtKB=A0A3Q1N8R7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000035969\|UniProtKB=O97716	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011120.4\|UniProtKB=F6ZL91	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845009925.1\|UniProtKB=A0A8I3NDL1	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000047374.1\|UniProtKB=A0A6I8PHB7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024621\|UniProtKB=P04625	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002898.4\|UniProtKB=G1KBE2	Anolis carolinensis	O
XENLA\|Gene=thra-b\|UniProtKB=P18115	Xenopus laevis	O
XENLA\|Gene=thra.S\|UniProtKB=A0A1L8EKN8	Xenopus laevis	O
XENLA\|Gene=thra.L\|UniProtKB=A0A8J0TQR7	Xenopus laevis	O
XENLA\|Gene=thra-a\|UniProtKB=P15204	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5966551\|UniProtKB=B3GR07	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016941.2\|UniProtKB=A0A3B3H792	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000012005.2\|UniProtKB=Q766D2	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000013012.1\|UniProtKB=W5N5X2	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000021968.1\|UniProtKB=H2XNI0	Ciona intestinalis	O
BRAFL\|Gene=LOC118405346\|UniProtKB=A0A9J7KIJ2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC584535\|UniProtKB=A0A7M7N2J7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O