PANTHER Gene Information

Gene Symbol(s):

RARA

Organism:

Gallus gallus

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Gene Name:

Retinoic acid receptor alpha

Gene ID:

ENSGALG00015025319

Protein ID:

Q90966

Persistent Id:

PTN001941345

Alternate Ids:

RARA_CHICK(UniProtKB-ID)	ENSGALP00015037410(Ensembl_PRO)
1089844(GI)	Q90967(AltAccession)
X73972(EMBL)	ENSGALG00015025319(Ensembl)
ENSGALT00015061755(Ensembl_TRS)	CAA52152(EMBL-CDS)
NR1B1(Synonym)	RARA(Symbol)
395213(GeneID)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	RETINOIC ACID RECEPTOR ALPHA (PTHR24082:SF115)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway intracellular receptor signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

Vitamin D metabolism and pathway

Retinoid X Receptor, Alpha

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, nuclear receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, response to retinoic acid, retinoic acid receptor signaling pathway, cell differentiation, positive regulation of transcription by RNA polymerase II, hindbrain morphogenesis
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RNA Polymerase II Transcription, Post-translational protein modification, SUMO E3 ligases SUMOylate target proteins, SUMOylation of intracellular receptors, Transcriptional regulation of granulopoiesis, Signaling by Nuclear Receptors, Signal Transduction, Signaling by Retinoic Acid, Nuclear Receptor transcription pathway, Gene expression (Transcription), Metabolism of proteins, SUMOylation, Developmental Biology, Generic Transcription Pathway

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9864\|UniProtKB=P10276	Homo sapiens	LDO
MACMU\|Ensembl=ENSMMUG00000012486.4\|UniProtKB=I0FG13	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97856\|UniProtKB=P11416	Mus musculus	LDO
RAT\|RGD=3534\|UniProtKB=A0A0G2JW78	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012500.6\|UniProtKB=F1MWQ3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017475.5\|UniProtKB=A0A480PNE7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023358.4\|UniProtKB=A0A3Q2KZX5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000028515.4\|UniProtKB=A0A2I2USN5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008607.1\|UniProtKB=A0A8I3MYI9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013112.3\|UniProtKB=A0A5F8GD96	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000041579.1\|UniProtKB=A0A6I8N103	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000002413.4\|UniProtKB=G1KAS4	Anolis carolinensis	LDO
DANRE\|ZFIN=ZDB-GENE-980526-72\|UniProtKB=Q7ZTI3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-284\|UniProtKB=Q90271	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000006945.3\|UniProtKB=F6VND6	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_116859\|UniProtKB=Q8MX80	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584535\|UniProtKB=A0A7M7N2J7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O