PANTHER Gene Information

Gene Symbol(s):

raraa

Organism:

Danio rerio

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Gene Name:

Retinoic acid receptor alpha-A

Gene ID:

ZDB-GENE-980526-284

Protein ID:

Q90271

Persistent Id:

PTN000637931

Alternate Ids:

Nuclear receptor subfamily 1 group B member 1-A(Synonym)	30680(GeneID)
BC092692(EMBL)	raraa{ECO:0000312\|ZFIN:ZDB-GENE-980526-284}(Symbol)
215024(GI)	AAA50049(EMBL-CDS)
Q91391(AltAccession)	NP_571481(refSeq)
ZDB-GENE-980526-284(ZFIN)	RARAA_DANRE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	RETINOIC ACID RECEPTOR ALPHA (PTHR24082:SF115)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway intracellular receptor signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

Vitamin D metabolism and pathway

Retinoid X Receptor, Alpha

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, response to retinoic acid, retinoic acid receptor signaling pathway, liver development, cell differentiation, regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, hindbrain morphogenesis
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by Retinoic Acid, Signaling by Nuclear Receptors, SUMO E3 ligases SUMOylate target proteins, Post-translational protein modification, Metabolism of proteins, Signal Transduction, Transcriptional regulation of granulopoiesis, SUMOylation of intracellular receptors, Developmental Biology, SUMOylation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9865\|UniProtKB=P10826	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014698.6\|UniProtKB=A0A2I3T0W6	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000007367.4\|UniProtKB=A0A1D5QJY1	Macaca mulatta	O
MOUSE\|MGI=MGI=97857\|UniProtKB=P22605	Mus musculus	O
RAT\|RGD=1584366\|UniProtKB=D3ZFD9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011518.6\|UniProtKB=G3X6X1	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000016976.3\|UniProtKB=A0A9L0R765	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000010409.6\|UniProtKB=M3WD77	Felis catus	O
MONDO\|Ensembl=ENSMODG00000014926.4\|UniProtKB=F7FVH3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046457.1\|UniProtKB=A0A6I8P5Y0	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002438\|UniProtKB=P22448	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009257.3\|UniProtKB=A0A803T6U7	Anolis carolinensis	O
HUMAN\|HGNC=9864\|UniProtKB=P10276	Homo sapiens	LDO
MACMU\|Ensembl=ENSMMUG00000012486.4\|UniProtKB=I0FG13	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97856\|UniProtKB=P11416	Mus musculus	LDO
RAT\|RGD=3534\|UniProtKB=A0A0G2JW78	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012500.6\|UniProtKB=F1MWQ3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017475.5\|UniProtKB=A0A480PNE7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023358.4\|UniProtKB=A0A3Q2KZX5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000028515.4\|UniProtKB=A0A2I2USN5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008607.1\|UniProtKB=A0A8I3MYI9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013112.3\|UniProtKB=A0A5F8GD96	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000041579.1\|UniProtKB=A0A6I8N103	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00015025319\|UniProtKB=Q90966	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002413.4\|UniProtKB=G1KAS4	Anolis carolinensis	LDO
CIOIN\|Ensembl=ENSCING00000006945.3\|UniProtKB=F6VND6	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_116859\|UniProtKB=Q8MX80	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584535\|UniProtKB=A0A7M7N2J7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O