PANTHER Gene Information   
Gene Symbol(s): RARA
Organism: Canis lupus familiaris
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Gene Name: Retinoic acid receptor alpha
Gene ID: ENSCAFG00845008607.1
Protein ID: A0A8I3MYI9
Persistent Id: PTN008393985
Alternate Ids:
ENSCAFP00845011756(Ensembl_PRO) XM_005624336(refSeq)
545510182(GI) A0A8I3MYI9_CANLF(UniProtKB-ID)
A0A8I3MYI9(Synonym) ENSCAFG00845008607(Ensembl)
ENSCAFT00845015144(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily: RETINOIC ACID RECEPTOR ALPHA (PTHR24082:SF115)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
signaling receptor activity
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
cell differentiation
hormone-mediated signaling pathway
intracellular receptor signaling pathway
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Vitamin D metabolism and pathway
   Retinoid X Receptor, Alpha
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: chromatin DNA binding, zinc ion binding, protein domain specific binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, alpha-actinin binding, DNA-binding transcription repressor activity, protein kinase B binding, retinoic acid-responsive element binding, signaling receptor binding, transcription coactivator binding, retinoic acid binding, nuclear receptor activity, protein kinase A binding
GO BP Complete: multicellular organism growth, negative regulation of cartilage development, negative regulation of miRNA transcription, positive regulation of cell population proliferation, ventricular cardiac muscle cell differentiation, positive regulation of cell cycle, positive regulation of transcription by RNA polymerase II, face development, glandular epithelial cell development, negative regulation of transcription by RNA polymerase II, outflow tract septum morphogenesis, retinoic acid receptor signaling pathway, neural tube closure, negative regulation of type II interferon production, negative regulation of tumor necrosis factor production, germ cell development, mRNA transcription by RNA polymerase II, embryonic camera-type eye development, limb development, chondroblast differentiation, spermatogenesis, Sertoli cell fate commitment, apoptotic cell clearance, regulation of hematopoietic progenitor cell differentiation, positive regulation of T-helper 2 cell differentiation, cellular response to estrogen stimulus, trachea cartilage development, positive regulation of interleukin-13 production, cellular response to lipopolysaccharide, ureteric bud development, growth plate cartilage development, cellular response to retinoic acid, negative regulation of apoptotic process, cell differentiation, negative regulation of granulocyte differentiation, positive regulation of interleukin-4 production, positive regulation of interleukin-5 production
GO CC Complete: nucleus, RNA polymerase II transcription regulator complex, actin cytoskeleton, cytosol, nucleolus, chromatin, plasma membrane, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Gene expression (Transcription), Signaling by Nuclear Receptors, Signal Transduction, Generic Transcription Pathway, Nuclear Receptor transcription pathway, RNA Polymerase II Transcription, Transcriptional regulation of granulopoiesis, Developmental Biology, Signaling by Retinoic Acid

Orthologs