PANTHER Gene Information   
Gene Symbol(s): Rara
Organism: Rattus norvegicus
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Gene Name: Retinoic acid receptor, alpha
Gene ID: 3534
Protein ID: A0A0G2JW78
Persistent Id: PTN002377627
Alternate Ids:
A0A0G2JW78_RAT(UniProtKB-ID) ENSRNOT00000084644(Ensembl_TRS)
24705(GeneID) XP_017452500(refSeq)
3534(RGD) ENSRNOP00000069776(Ensembl_PRO)
ENSRNOG00000009972(Ensembl) 1046848443(GI)
A0A0G2JW78(Synonym)
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PANTHER Classification
PANTHER Family: NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily: RETINOIC ACID RECEPTOR ALPHA (PTHR24082:SF115)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
signaling receptor activity
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
cell differentiation
hormone-mediated signaling pathway
intracellular receptor signaling pathway
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Vitamin D metabolism and pathway
   Retinoid X Receptor, Alpha

GO MF Complete: heterocyclic compound binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription cis-regulatory region binding, alpha-actinin binding, protein kinase B binding, sequence-specific DNA binding, transcription coactivator binding, DNA-binding transcription factor activity, mRNA 5'-UTR binding, nuclear receptor activity, chromatin DNA binding, zinc ion binding, protein domain specific binding, histone deacetylase binding, mRNA regulatory element binding translation repressor activity, DNA-binding transcription repressor activity, chromatin binding, retinoic acid-responsive element binding, signaling receptor binding, retinoic acid binding, DNA binding, sequence-specific double-stranded DNA binding, enzyme binding, protein kinase A binding
GO BP Complete: male gonad development, ventricular cardiac muscle cell differentiation, face development, response to retinoic acid, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, regulation of synaptic plasticity, negative regulation of type II interferon production, negative regulation of translation, negative regulation of tumor necrosis factor production, mRNA transcription by RNA polymerase II, embryonic camera-type eye development, chondroblast differentiation, apoptotic cell clearance, regulation of apoptotic process, negative regulation of gene expression, growth plate cartilage development, positive regulation of gene expression, response to estradiol, prostate gland development, negative regulation of granulocyte differentiation, positive regulation of interleukin-4 production, regulation of granulocyte differentiation, positive regulation of interleukin-5 production, response to cytokine, multicellular organism growth, negative regulation of cartilage development, negative regulation of miRNA transcription, negative regulation of cell population proliferation, positive regulation of cell population proliferation, positive regulation of neuron differentiation, positive regulation of cell cycle, protein phosphorylation, positive regulation of transcription by RNA polymerase II, glandular epithelial cell development, bone development, negative regulation of transcription by RNA polymerase II, outflow tract septum morphogenesis, response to ethanol, retinoic acid receptor signaling pathway, neural tube closure, negative regulation of cell differentiation, liver development, germ cell development, limb development, spermatogenesis, Sertoli cell fate commitment, regulation of hematopoietic progenitor cell differentiation, regulation of DNA-templated transcription, female pregnancy, hippocampus development, positive regulation of T-helper 2 cell differentiation, cellular response to estrogen stimulus, trachea cartilage development, positive regulation of interleukin-13 production, cellular response to lipopolysaccharide, ureteric bud development, cellular response to retinoic acid, negative regulation of apoptotic process, cell differentiation, regulation of myelination, response to vitamin A
GO CC Complete: RNA polymerase II transcription regulator complex, nucleolus, chromatin, plasma membrane, nucleoplasm, nucleus, transcription regulator complex, dendrite, perinuclear region of cytoplasm, cytoplasm, actin cytoskeleton, cytosol, protein-containing complex
Reactome Pathways: Transcriptional regulation of granulopoiesis, Signaling by Retinoic Acid, SUMOylation of intracellular receptors, Signal Transduction, Metabolism of proteins, Post-translational protein modification, RNA Polymerase II Transcription, Nuclear Receptor transcription pathway, Signaling by Nuclear Receptors, Generic Transcription Pathway, SUMO E3 ligases SUMOylate target proteins, SUMOylation, Developmental Biology, Gene expression (Transcription)