PANTHER Gene Information

Gene Symbol(s):

thrb

Organism:

Xenopus tropicalis

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Gene Name:

Thyroid hormone receptor beta isoform X1

Gene ID:

XB-GENE-6070709

Protein ID:

E7CYG4

Persistent Id:

PTN008605234

Alternate Ids:

ENSXETP00000078376(Ensembl_PRO)	302954190(GI)
ENSXETG00000003871(Ensembl)	XM_012964865(refSeq)
E7CYG4(Synonym)	ENSXETT00000081880(Ensembl_TRS)
E7CYG4_XENTR(UniProtKB-ID)	ADL74878(EMBL-CDS)
734147(GeneID)	HM849045(EMBL)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	THYROID HORMONE RECEPTOR BETA (PTHR24082:SF210)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway intracellular receptor signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	RNA polymerase II transcription regulator complex
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, retinoic acid receptor signaling pathway, notochord regression, cell differentiation, regulation of DNA-templated transcription, thyroid hormone receptor signaling pathway, positive regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, RNA polymerase II transcription regulator complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Generic Transcription Pathway, Nuclear Receptor transcription pathway, RNA Polymerase II Transcription, Gene expression (Transcription)

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11799\|UniProtKB=P10828	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014697.6\|UniProtKB=H2R3K3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007268.3\|UniProtKB=G3S6W6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000067.4\|UniProtKB=F7G9B9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98743\|UniProtKB=P37242	Mus musculus	LDO
RAT\|RGD=3858\|UniProtKB=P18113	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017802.6\|UniProtKB=G3X7C1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036033.3\|UniProtKB=A0A286ZWA8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019007.4\|UniProtKB=F7E341	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022754.4\|UniProtKB=A0A2I2UAC2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019516.1\|UniProtKB=A0A8I3P5V7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014903.4\|UniProtKB=A0A5F8GH58	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012237.4\|UniProtKB=A0A6I8NFL6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001557\|UniProtKB=P68306	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011465.4\|UniProtKB=R4GD38	Anolis carolinensis	LDO
XENLA\|Gene=thrb-b\|UniProtKB=P18119	Xenopus laevis	O
XENLA\|Gene=thrb.S\|UniProtKB=A0A1L8FRG8	Xenopus laevis	O
XENLA\|Gene=thrb-a\|UniProtKB=P18117	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000008122.2\|UniProtKB=H2LVQ7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-268\|UniProtKB=Q9PVE4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006846.1\|UniProtKB=W5MIT5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021968.1\|UniProtKB=H2XNI0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405346\|UniProtKB=A0A9J7KIJ2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584535\|UniProtKB=A0A7M7N2J7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O