PANTHER Gene Information

Gene Symbol(s):

ppara3

Organism:

Danio rerio

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Gene Name:

Peroxisome proliferator-activated receptor alpha

Gene ID:

ZDB-GENE-041210-169

Protein ID:

A0A8M1NRP3

Persistent Id:

PTN000638022

Alternate Ids:

563298(GeneID)	ENSDARP00000107246(Ensembl_PRO)
ENSDART00000125361(Ensembl_TRS)	ZDB-GENE-041210-169(ZFIN)
A0A8M1NRP3_DANRE(UniProtKB-ID)	NP_001154805(refSeq)
BX649425(EMBL)	A0A8M1NRP3(Synonym)
528476499(GI)	ENSDARG00000031777(Ensembl)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PTHR24082:SF197)
PANTHER GO-slim Molecular Function:	DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II negative regulation of inflammatory response regulation of lipid metabolic process cell differentiation regulation of localization fatty acid metabolic process hormone-mediated signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

PPARalpha/gamma

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of inflammatory response, cell differentiation, regulation of DNA-templated transcription, negative regulation of cholesterol storage, positive regulation of transcription by RNA polymerase II, positive regulation of fatty acid metabolic process, fatty acid metabolic process, hormone-mediated signaling pathway
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9232\|UniProtKB=Q07869	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014505.6\|UniProtKB=H2QLW3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000042788.1\|UniProtKB=A0A2I2Z0P2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016258.4\|UniProtKB=G7N476	Macaca mulatta	O
MOUSE\|MGI=MGI=104740\|UniProtKB=P23204	Mus musculus	O
RAT\|RGD=3369\|UniProtKB=P37230	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000008063.5\|UniProtKB=Q5EA13	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000006.5\|UniProtKB=F1SM76	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000484.4\|UniProtKB=A0A9L0T8I5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005547.5\|UniProtKB=M3W486	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010405.1\|UniProtKB=A0A8I3NDH4	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00805026790\|UniProtKB=Q95N78	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000007365.3\|UniProtKB=F7ADB3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000006277.2\|UniProtKB=F6VPM6	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023058.1\|UniProtKB=A0A1D5PJQ2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004788.3\|UniProtKB=G1KD82	Anolis carolinensis	O
XENLA\|Gene=ppara\|UniProtKB=P37232	Xenopus laevis	O
XENLA\|Gene=ppara.S\|UniProtKB=Q6PAY0	Xenopus laevis	O
XENLA\|Gene=ppara.L\|UniProtKB=Q5PPL6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-480229\|UniProtKB=F7C0K4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000011091.2\|UniProtKB=H2M628	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002413.2\|UniProtKB=H2LAT3	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000017030.1\|UniProtKB=W5NK92	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000013188.2\|UniProtKB=Q4H2X6	Ciona intestinalis	O
BRAFL\|Gene=LOC118405726\|UniProtKB=A0A9J7HKH0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC579208\|UniProtKB=A0A7M7RDK4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576339\|UniProtKB=A0A7M7NVX1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O