PANTHER Gene Information   
Gene Symbol(s): PPARA
Organism: Macaca mulatta
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Gene Name: Peroxisome proliferator-activated receptor alpha
Gene ID: ENSMMUG00000016258.4
Protein ID: G7N476
Persistent Id: PTN000638004
Alternate Ids:
ENSMMUP00000021366(Ensembl_PRO) G7N476_MACMU(UniProtKB-ID)
ENSMMUG00000016258(Ensembl) G7N476(Synonym)
ENSMMUT00000022843(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily: PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PTHR24082:SF197)  
PANTHER GO-slim Molecular Function: DNA-binding transcription repressor activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
signaling receptor activity
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
negative regulation of inflammatory response
regulation of lipid metabolic process
cell differentiation
regulation of localization
fatty acid metabolic process
hormone-mediated signaling pathway
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   PPARalpha/gamma
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, signaling receptor activity, DNA-binding transcription activator activity, RNA polymerase II-specific, lipid binding, sequence-specific DNA binding, DNA-binding transcription activator activity, DNA-binding transcription repressor activity, RNA polymerase II-specific, DNA binding, DNA-binding transcription factor activity, ubiquitin conjugating enzyme binding, RNA polymerase II-specific DNA-binding transcription factor binding, nuclear receptor activity, metal ion binding, nuclear steroid receptor activity
GO BP Complete: negative regulation of appetite, negative regulation of miRNA transcription, positive regulation of ATP biosynthetic process, epidermis development, negative regulation of glycolytic process, negative regulation of cytokine production involved in inflammatory response, regulation of circadian rhythm, positive regulation of transcription by RNA polymerase II, steroid hormone receptor signaling pathway, positive regulation of fatty acid metabolic process, positive regulation of gluconeogenesis, negative regulation of reactive oxygen species biosynthetic process, negative regulation of hepatocyte apoptotic process, hormone-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, circadian regulation of gene expression, wound healing, positive regulation of fatty acid oxidation, enamel mineralization, positive regulation of DNA-templated transcription, peroxisome proliferator activated receptor signaling pathway, intracellular receptor signaling pathway, gluconeogenesis, negative regulation of sequestering of triglyceride, negative regulation of inflammatory response, positive regulation of transformation of host cell by virus, regulation of DNA-templated transcription, negative regulation of leukocyte cell-cell adhesion, cellular response to starvation, fatty acid metabolic process, regulation of transcription by RNA polymerase II, positive regulation of lipid biosynthetic process, regulation of gene expression, cell differentiation, negative regulation of macrophage derived foam cell differentiation, negative regulation of cholesterol storage, regulation of ketone metabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of fatty acid metabolic process, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete: nucleus, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs