PANTHER Gene Information   
Gene Symbol(s): PPARA
Organism: Sus scrofa
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Gene Name: Peroxisome proliferator-activated receptor alpha
Gene ID: ENSSSCG00000000006.5
Protein ID: F1SM76
Persistent Id: PTN001532656
Alternate Ids:
F1SM76_PIG(UniProtKB-ID) ENSSSCP00000000007(Ensembl_PRO)
F1SM76(Synonym) ENSSSCT00000000007(Ensembl_TRS)
ENSSSCG00000000006(Ensembl)
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PANTHER Classification
PANTHER Family: NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily: PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PTHR24082:SF197)  
PANTHER GO-slim Molecular Function: DNA-binding transcription repressor activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
signaling receptor activity
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
negative regulation of inflammatory response
regulation of lipid metabolic process
cell differentiation
regulation of localization
fatty acid metabolic process
hormone-mediated signaling pathway
positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   PPARalpha/gamma

GO MF Complete: zinc ion binding, ubiquitin conjugating enzyme binding, RNA polymerase II-specific DNA-binding transcription factor binding, nuclear receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, nuclear steroid receptor activity, DNA-binding transcription activator activity, RNA polymerase II-specific, lipid binding, DNA-binding transcription repressor activity, RNA polymerase II-specific
GO BP Complete: negative regulation of appetite, negative regulation of miRNA transcription, positive regulation of ATP biosynthetic process, epidermis development, negative regulation of glycolytic process, negative regulation of cytokine production involved in inflammatory response, regulation of circadian rhythm, positive regulation of transcription by RNA polymerase II, steroid hormone receptor signaling pathway, positive regulation of fatty acid metabolic process, positive regulation of gluconeogenesis, negative regulation of reactive oxygen species biosynthetic process, negative regulation of hepatocyte apoptotic process, hormone-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, circadian regulation of gene expression, wound healing, positive regulation of fatty acid oxidation, enamel mineralization, peroxisome proliferator activated receptor signaling pathway, gluconeogenesis, negative regulation of sequestering of triglyceride, negative regulation of inflammatory response, positive regulation of transformation of host cell by virus, negative regulation of leukocyte cell-cell adhesion, cellular response to starvation, fatty acid metabolic process, positive regulation of lipid biosynthetic process, cell differentiation, negative regulation of macrophage derived foam cell differentiation, negative regulation of cholesterol storage, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete: nucleus, nucleoplasm
Reactome Pathways: Metabolism, Metabolism of lipids, Regulation of lipid metabolism by PPARalpha, Nuclear Receptor transcription pathway, Generic Transcription Pathway, SUMOylation of intracellular receptors, SUMO E3 ligases SUMOylate target proteins, SUMOylation, Metabolism of proteins, RNA Polymerase II Transcription, Post-translational protein modification, Gene expression (Transcription)