PANTHER Gene Information

Gene Symbol(s):

ppara.S

Organism:

Xenopus laevis

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Gene Name:

Peroxisome proliferator-activated receptor alpha

Gene ID:

ppara.S

Protein ID:

Q6PAY0

Persistent Id:

PTN009080367

Alternate Ids:

398843(GeneID)	BC060004(EMBL)
Q6PAY0_XENLA(UniProtKB-ID)	Q6PAY0(Synonym)
148235186(GI)	NM_001089813(refSeq)
AAH60004(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PTHR24082:SF197)
PANTHER GO-slim Molecular Function:	DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II negative regulation of inflammatory response regulation of lipid metabolic process cell differentiation regulation of localization fatty acid metabolic process hormone-mediated signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

PPARalpha/gamma

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, lipid binding, sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of inflammatory response, cell differentiation, regulation of DNA-templated transcription, negative regulation of cholesterol storage, positive regulation of transcription by RNA polymerase II, positive regulation of fatty acid metabolic process, fatty acid metabolic process, regulation of transcription by RNA polymerase II, hormone-mediated signaling pathway
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9232\|UniProtKB=Q07869	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014505.6\|UniProtKB=H2QLW3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000042788.1\|UniProtKB=A0A2I2Z0P2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016258.4\|UniProtKB=G7N476	Macaca mulatta	O
MOUSE\|MGI=MGI=104740\|UniProtKB=P23204	Mus musculus	O
RAT\|RGD=3369\|UniProtKB=P37230	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000008063.5\|UniProtKB=Q5EA13	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000006.5\|UniProtKB=F1SM76	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000484.4\|UniProtKB=A0A9L0T8I5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005547.5\|UniProtKB=M3W486	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010405.1\|UniProtKB=A0A8I3NDH4	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00805026790\|UniProtKB=Q95N78	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000007365.3\|UniProtKB=F7ADB3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000006277.2\|UniProtKB=F6VPM6	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023058.1\|UniProtKB=A0A1D5PJQ2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004788.3\|UniProtKB=G1KD82	Anolis carolinensis	O
XENTR\|Xenbase=XB-GENE-480229\|UniProtKB=F7C0K4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000011091.2\|UniProtKB=H2M628	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002413.2\|UniProtKB=H2LAT3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041210-169\|UniProtKB=A0A8M1NRP3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-990415-211\|UniProtKB=A6XMH7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017030.1\|UniProtKB=W5NK92	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000013188.2\|UniProtKB=Q4H2X6	Ciona intestinalis	O
BRAFL\|Gene=LOC118405726\|UniProtKB=A0A9J7HKH0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC579208\|UniProtKB=A0A7M7RDK4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576339\|UniProtKB=A0A7M7NVX1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O