PANTHER Gene Information

Gene Symbol(s):

DEFA12

Organism:

Equus caballus

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Gene Name:

Paneth cell-specific alpha-defensin 12

Gene ID:

ENSECAG00000054883.1

Protein ID:

C8BNG5

Persistent Id:

PTN008984478

Alternate Ids:

C8BNG5_HORSE(UniProtKB-ID)	257167929(GI)
ENSECAG00000054883(Ensembl)	NM_001166071(refSeq)
ACV49738(EMBL-CDS)	GQ259775(EMBL)
ENSECAT00000034810(Ensembl_TRS)	C8BNG5(Synonym)
100306984(GeneID)	ENSECAP00000036619(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	ALPHA-DEFENSIN 1 (PTHR11876)
PANTHER Subfamily:	ALPHA-DEFENSIN 1 (PTHR11876:SF28)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular matrix extracellular space
PANTHER protein class:	antimicrobial response protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	-
GO BP Complete:	disruption of plasma membrane integrity in another organism, innate immune response in mucosa, defense response to Gram-negative bacterium, cellular response to lipopolysaccharide, antibacterial humoral response, defense response, defense response to bacterium, defense response to Gram-positive bacterium, antimicrobial humoral immune response mediated by antimicrobial peptide
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
GORGO\|Ensembl=ENSGGOG00000039811.1\|UniProtKB=A0A2I2YQC3	Gorilla gorilla gorilla	O
MACMU\|Gene=RTD3_MACMU\|UniProtKB=Q9GLR2	Macaca mulatta	O
MACMU\|Gene=RTD1B\|UniProtKB=P82271	Macaca mulatta	O
MACMU\|Gene=RTD1A\|UniProtKB=P82270	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000049881.1\|UniProtKB=A0A5F8AES1	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054742.1\|UniProtKB=A0A5F7Z7A6	Macaca mulatta	O
HUMAN\|HGNC=2763\|UniProtKB=P12838	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000034369\|UniProtKB=Q5G862	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010900.3\|UniProtKB=G3R5N8	Gorilla gorilla gorilla	O
HUMAN\|HGNC=2765\|UniProtKB=Q01524	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000051516\|UniProtKB=Q5G860	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010901.3\|UniProtKB=G3R5P2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000052512.1\|UniProtKB=F7DMC6	Macaca mulatta	O
PANTR\|Gene=DEFA7\|UniProtKB=Q5G859	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000040805.1\|UniProtKB=A0A2I2Y9B9	Gorilla gorilla gorilla	O
HUMAN\|HGNC=2762\|UniProtKB=P59666	Homo sapiens	O
HUMAN\|HGNC=2761\|UniProtKB=P59665	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000050573\|UniProtKB=Q5G863	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004514.3\|UniProtKB=G3QPD5	Gorilla gorilla gorilla	O
MACMU\|Gene=DEF8_MACMU\|UniProtKB=P60032	Macaca mulatta	O
MACMU\|Gene=DEF3_MACMU\|UniProtKB=P60031	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000018517\|UniProtKB=P60030	Macaca mulatta	O
HUMAN\|HGNC=2764\|UniProtKB=Q01523	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000049316\|UniProtKB=Q5G861	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016102.3\|UniProtKB=G3RJ35	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000040721.2\|UniProtKB=A0A1D5QQV7	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000045717.2\|UniProtKB=F7DY92	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054369.1\|UniProtKB=A0A5F7ZH18	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054195.1\|UniProtKB=A0A5F8AQZ0	Macaca mulatta	O
MACMU\|Gene=DEF4_MACMU\|UniProtKB=P82319	Macaca mulatta	O
MACMU\|Gene=DEF6_MACMU\|UniProtKB=P82320	Macaca mulatta	O
MOUSE\|MGI=MGI=99592\|UniProtKB=P17534	Mus musculus	O
MOUSE\|MGI=MGI=3705236\|UniProtKB=K9J724	Mus musculus	O
MOUSE\|MGI=MGI=3630385\|UniProtKB=Q5G864	Mus musculus	O
MOUSE\|MGI=MGI=3642780\|UniProtKB=F2Z403	Mus musculus	O
MOUSE\|MGI=MGI=94881\|UniProtKB=P17533	Mus musculus	O
MOUSE\|MGI=MGI=94883\|UniProtKB=P28310	Mus musculus	O
MOUSE\|MGI=MGI=94882\|UniProtKB=P28309	Mus musculus	O
MOUSE\|MGI=MGI=102516\|UniProtKB=Q64263	Mus musculus	O
MOUSE\|MGI=MGI=3709048\|UniProtKB=D3Z0J0	Mus musculus	O
MOUSE\|MGI=MGI=94880\|UniProtKB=P11477	Mus musculus	O
MOUSE\|MGI=MGI=99581\|UniProtKB=P50705	Mus musculus	O
MOUSE\|MGI=MGI=99584\|UniProtKB=P28311	Mus musculus	O
MOUSE\|MGI=MGI=3630390\|UniProtKB=Q3L180	Mus musculus	O
MOUSE\|MGI=MGI=3630381\|UniProtKB=Q5G866	Mus musculus	O
MOUSE\|MGI=MGI=99579\|UniProtKB=P50707	Mus musculus	O
MOUSE\|MGI=MGI=102514\|UniProtKB=P50716	Mus musculus	O
MOUSE\|MGI=MGI=99583\|UniProtKB=P28312	Mus musculus	O
MOUSE\|MGI=MGI=99580\|UniProtKB=P50706	Mus musculus	O
MOUSE\|MGI=MGI=3645033\|UniProtKB=D3YX03	Mus musculus	O
MOUSE\|MGI=MGI=3630303\|UniProtKB=Q5ERI8	Mus musculus	O
MOUSE\|MGI=MGI=99582\|UniProtKB=P50704	Mus musculus	O
MOUSE\|MGI=MGI=3711900\|UniProtKB=E9QLQ1	Mus musculus	O
MOUSE\|MGI=MGI=99591\|UniProtKB=P50708	Mus musculus	O
MOUSE\|MGI=MGI=99586\|UniProtKB=P50713	Mus musculus	O
MOUSE\|MGI=MGI=1915259\|UniProtKB=Q45VN2	Mus musculus	O
MOUSE\|MGI=MGI=99588\|UniProtKB=P50711	Mus musculus	O
MOUSE\|MGI=MGI=3611585\|UniProtKB=Q9D848	Mus musculus	O
MOUSE\|MGI=MGI=3646688\|UniProtKB=D3Z1V9	Mus musculus	O
MOUSE\|MGI=MGI=102509\|UniProtKB=P50715	Mus musculus	O
MOUSE\|MGI=MGI=3639039\|UniProtKB=Q8C1N8	Mus musculus	O
MOUSE\|MGI=MGI=3630383\|UniProtKB=Q5G865	Mus musculus	O
MOUSE\|MGI=MGI=1913548\|UniProtKB=Q8C1P2	Mus musculus	O
MOUSE\|MGI=MGI=99590\|UniProtKB=P50709	Mus musculus	O
MOUSE\|MGI=MGI=3708769\|UniProtKB=L7N231	Mus musculus	O
MOUSE\|MGI=MGI=3705230\|UniProtKB=D3YX02	Mus musculus	O
MOUSE\|MGI=MGI=99585\|UniProtKB=P50714	Mus musculus	O
MOUSE\|MGI=MGI=3709605\|UniProtKB=Q5ERJ0	Mus musculus	O
MOUSE\|MGI=MGI=1345152\|UniProtKB=Q64016	Mus musculus	O
MOUSE\|MGI=MGI=99587\|UniProtKB=P50712	Mus musculus	O
MOUSE\|MGI=MGI=3808881\|UniProtKB=E9QPZ2	Mus musculus	O
RAT\|RGD=1304852\|UniProtKB=Q4JEI9	Rattus norvegicus	O
RAT\|RGD=1566065\|UniProtKB=Q4JEI6	Rattus norvegicus	O
RAT\|RGD=1562293\|UniProtKB=Q4JEI8	Rattus norvegicus	O
RAT\|Gene=DEF5_RAT\|UniProtKB=P82106	Rattus norvegicus	O
RAT\|RGD=1564555\|UniProtKB=Q4JEI5	Rattus norvegicus	O
RAT\|RGD=150344900\|UniProtKB=A0A8I6GLV0	Rattus norvegicus	O
RAT\|RGD=1561398\|UniProtKB=Q4JEI2	Rattus norvegicus	O
RAT\|RGD=1587186\|UniProtKB=Q4JEI3	Rattus norvegicus	O
RAT\|Gene=DEF3A_RAT\|UniProtKB=Q62713	Rattus norvegicus	O
RAT\|Ensembl=ENSRNOG00000038135\|UniProtKB=Q9Z1F1	Rattus norvegicus	O
RAT\|RGD=727857\|UniProtKB=Q62714	Rattus norvegicus	O
RAT\|RGD=727951\|UniProtKB=Q62715	Rattus norvegicus	O
RAT\|RGD=1587187\|UniProtKB=F1LSU5	Rattus norvegicus	O
RAT\|Gene=DEF1_RAT\|UniProtKB=Q62716	Rattus norvegicus	O
ORNAN\|Gene=DEFA2_ORNAN\|UniProtKB=P0C8A2	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000037525.1\|UniProtKB=A0A6I8PB05	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000050290\|UniProtKB=P0C8A3	Ornithorhynchus anatinus	O
TRIAD\|EnsemblGenome=TriadG55945\|UniProtKB=B3RTJ3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55948\|UniProtKB=B3RTJ6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55947\|UniProtKB=B3RTJ5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63910\|UniProtKB=B3RTJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63869\|UniProtKB=B3RVQ0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55946\|UniProtKB=B3RTJ4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55949\|UniProtKB=B3RTJ7	Trichoplax adhaerens	O