PANTHER Gene Information

Gene Symbol(s):

DEFA6

Organism:

Macaca mulatta

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Gene Name:

Defensin alpha 6

Gene ID:

ENSMMUG00000052512.1

Protein ID:

F7DMC6

Persistent Id:

PTN008331693

Alternate Ids:

F7DMC6_MACMU(UniProtKB-ID)	XM_001098733(refSeq)
ENSMMUT00000097813(Ensembl_TRS)	ENSMMUP00000063497(Ensembl_PRO)
F7DMC6(Synonym)	717000(GeneID)
109085533(GI)	ENSMMUG00000052512(Ensembl)
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PANTHER Classification

PANTHER Family:	ALPHA-DEFENSIN 1 (PTHR11876)
PANTHER Subfamily:	DEFENSIN-6 (PTHR11876:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cellular response to lipopolysaccharide defense response to Gram-negative bacterium antibacterial humoral response innate immune response antimicrobial humoral immune response mediated by antimicrobial peptide defense response to Gram-positive bacterium
PANTHER GO-slim Cellular Component:	extracellular matrix extracellular space
PANTHER protein class:	antimicrobial response protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein homodimerization activity
GO BP Complete:	disruption of plasma membrane integrity in another organism, innate immune response in mucosa, defense response to Gram-negative bacterium, cellular response to lipopolysaccharide, killing of cells of another organism, antibacterial humoral response, defense response, defense response to fungus, defense response to bacterium, defense response to Gram-positive bacterium, antimicrobial humoral immune response mediated by antimicrobial peptide
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2763\|UniProtKB=P12838	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000034369\|UniProtKB=Q5G862	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010900.3\|UniProtKB=G3R5N8	Gorilla gorilla gorilla	O
HUMAN\|HGNC=2765\|UniProtKB=Q01524	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051516\|UniProtKB=Q5G860	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010901.3\|UniProtKB=G3R5P2	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=99592\|UniProtKB=P17534	Mus musculus	O
MOUSE\|MGI=MGI=3705236\|UniProtKB=K9J724	Mus musculus	O
MOUSE\|MGI=MGI=3630385\|UniProtKB=Q5G864	Mus musculus	O
MOUSE\|MGI=MGI=3642780\|UniProtKB=F2Z403	Mus musculus	O
MOUSE\|MGI=MGI=94881\|UniProtKB=P17533	Mus musculus	O
MOUSE\|MGI=MGI=94883\|UniProtKB=P28310	Mus musculus	O
MOUSE\|MGI=MGI=94882\|UniProtKB=P28309	Mus musculus	O
MOUSE\|MGI=MGI=102516\|UniProtKB=Q64263	Mus musculus	O
MOUSE\|MGI=MGI=3709048\|UniProtKB=D3Z0J0	Mus musculus	O
MOUSE\|MGI=MGI=94880\|UniProtKB=P11477	Mus musculus	O
MOUSE\|MGI=MGI=99581\|UniProtKB=P50705	Mus musculus	O
MOUSE\|MGI=MGI=99584\|UniProtKB=P28311	Mus musculus	O
MOUSE\|MGI=MGI=3630390\|UniProtKB=Q3L180	Mus musculus	O
MOUSE\|MGI=MGI=3630381\|UniProtKB=Q5G866	Mus musculus	O
MOUSE\|MGI=MGI=99579\|UniProtKB=P50707	Mus musculus	O
MOUSE\|MGI=MGI=102514\|UniProtKB=P50716	Mus musculus	O
MOUSE\|MGI=MGI=99583\|UniProtKB=P28312	Mus musculus	O
MOUSE\|MGI=MGI=99580\|UniProtKB=P50706	Mus musculus	O
MOUSE\|MGI=MGI=3645033\|UniProtKB=D3YX03	Mus musculus	O
MOUSE\|MGI=MGI=3630303\|UniProtKB=Q5ERI8	Mus musculus	O
MOUSE\|MGI=MGI=99582\|UniProtKB=P50704	Mus musculus	O
MOUSE\|MGI=MGI=3711900\|UniProtKB=E9QLQ1	Mus musculus	O
MOUSE\|MGI=MGI=99591\|UniProtKB=P50708	Mus musculus	O
MOUSE\|MGI=MGI=99586\|UniProtKB=P50713	Mus musculus	O
MOUSE\|MGI=MGI=1915259\|UniProtKB=Q45VN2	Mus musculus	O
MOUSE\|MGI=MGI=99588\|UniProtKB=P50711	Mus musculus	O
MOUSE\|MGI=MGI=3611585\|UniProtKB=Q9D848	Mus musculus	O
MOUSE\|MGI=MGI=3646688\|UniProtKB=D3Z1V9	Mus musculus	O
MOUSE\|MGI=MGI=102509\|UniProtKB=P50715	Mus musculus	O
MOUSE\|MGI=MGI=3639039\|UniProtKB=Q8C1N8	Mus musculus	O
MOUSE\|MGI=MGI=3630383\|UniProtKB=Q5G865	Mus musculus	O
MOUSE\|MGI=MGI=1913548\|UniProtKB=Q8C1P2	Mus musculus	O
MOUSE\|MGI=MGI=99590\|UniProtKB=P50709	Mus musculus	O
MOUSE\|MGI=MGI=3708769\|UniProtKB=L7N231	Mus musculus	O
MOUSE\|MGI=MGI=3705230\|UniProtKB=D3YX02	Mus musculus	O
MOUSE\|MGI=MGI=99585\|UniProtKB=P50714	Mus musculus	O
MOUSE\|MGI=MGI=3709605\|UniProtKB=Q5ERJ0	Mus musculus	O
MOUSE\|MGI=MGI=1345152\|UniProtKB=Q64016	Mus musculus	O
MOUSE\|MGI=MGI=99587\|UniProtKB=P50712	Mus musculus	O
MOUSE\|MGI=MGI=3808881\|UniProtKB=E9QPZ2	Mus musculus	O
RAT\|RGD=1304852\|UniProtKB=Q4JEI9	Rattus norvegicus	O
RAT\|RGD=1566065\|UniProtKB=Q4JEI6	Rattus norvegicus	O
RAT\|RGD=1562293\|UniProtKB=Q4JEI8	Rattus norvegicus	O
RAT\|Gene=DEF5_RAT\|UniProtKB=P82106	Rattus norvegicus	O
RAT\|RGD=1564555\|UniProtKB=Q4JEI5	Rattus norvegicus	O
RAT\|RGD=150344900\|UniProtKB=A0A8I6GLV0	Rattus norvegicus	O
RAT\|RGD=1561398\|UniProtKB=Q4JEI2	Rattus norvegicus	O
RAT\|RGD=1587186\|UniProtKB=Q4JEI3	Rattus norvegicus	O
RAT\|Gene=DEF3A_RAT\|UniProtKB=Q62713	Rattus norvegicus	O
RAT\|Ensembl=ENSRNOG00000038135\|UniProtKB=Q9Z1F1	Rattus norvegicus	O
RAT\|RGD=727857\|UniProtKB=Q62714	Rattus norvegicus	O
RAT\|RGD=727951\|UniProtKB=Q62715	Rattus norvegicus	O
RAT\|RGD=1587187\|UniProtKB=F1LSU5	Rattus norvegicus	O
RAT\|Gene=DEF1_RAT\|UniProtKB=Q62716	Rattus norvegicus	O
HORSE\|Ensembl=ENSECAG00000049963.1\|UniProtKB=C8BNH6	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000030501.2\|UniProtKB=C8BNG1	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000033357.1\|UniProtKB=C8BNI9	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000011787\|UniProtKB=A6YB85	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000027869.3\|UniProtKB=A0A3Q2HQJ5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039434.1\|UniProtKB=A0A3Q2GSZ3	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000032644.1\|UniProtKB=A0A3Q2IBF0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000028505.2\|UniProtKB=A0A3Q2L6V2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000043705.2\|UniProtKB=A0A5F5PG18	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000054883.1\|UniProtKB=C8BNG5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000037168.3\|UniProtKB=A0A5F5PU65	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000051382.1\|UniProtKB=F6WLD2	Equus caballus	O
ORNAN\|Gene=DEFA2_ORNAN\|UniProtKB=P0C8A2	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000037525.1\|UniProtKB=A0A6I8PB05	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000050290\|UniProtKB=P0C8A3	Ornithorhynchus anatinus	O
TRIAD\|EnsemblGenome=TriadG55945\|UniProtKB=B3RTJ3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55948\|UniProtKB=B3RTJ6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55947\|UniProtKB=B3RTJ5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63910\|UniProtKB=B3RTJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63869\|UniProtKB=B3RVQ0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55946\|UniProtKB=B3RTJ4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55949\|UniProtKB=B3RTJ7	Trichoplax adhaerens	O