PANTHER Gene Information

Gene Symbol(s):

8052988

Organism:

Ixodes scapularis

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Gene Name:

Ubiquitin protein ligase

Gene ID:

ISCW018551

Protein ID:

B7PKN3

Persistent Id:

PTN001177075

Alternate Ids:

ABJB010311023(EMBL)	XP_002434331(refSeq)
241999376(GI)	B7PKN3_IXOSC(UniProtKB-ID)
B7PKN3(Synonym)	ISCW018551(Ensembl)
ISCW018551-PA(Ensembl_PRO)	EEC07155(EMBL-CDS)
ISCW018551-RA(Ensembl_TRS)	8052988(GeneID)
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PANTHER Classification

PANTHER Family:	UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily:	UBIQUITIN-CONJUGATING ENZYME E2-17 KDA (PTHR24068:SF74)
PANTHER GO-slim Molecular Function:	ubiquitin conjugating enzyme activity
PANTHER GO-slim Biological Process:	protein polyubiquitination
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

Ubiquitin proteasome pathway

Ubiquitin-conjugating enzyme E2

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin-protein transferase activity, ATP binding, ubiquitin conjugating enzyme activity, transferase activity, ligase activity
GO BP Complete:	protein polyubiquitination, ubiquitin-dependent protein catabolic process
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
CIOIN\|Ensembl=ENSCING00000003855.3\|UniProtKB=A0A1W2WIY7	Ciona intestinalis	O
BRAFL\|Gene=LOC118411439\|UniProtKB=A0A9J7MJH5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC591005\|UniProtKB=A0A7M7SVW9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891780\|UniProtKB=A0A7M7SVX6	Strongylocentrotus purpuratus	O
HUMAN\|HGNC=12474\|UniProtKB=P51668	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002518.6\|UniProtKB=H2Q1X5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004811.3\|UniProtKB=A0A2I2YMV6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019825.4\|UniProtKB=G7N2F6	Macaca mulatta	O
MOUSE\|MGI=MGI=2384911\|UniProtKB=P61080	Mus musculus	O
RAT\|RGD=1307886\|UniProtKB=D3ZDK2	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020796\|UniProtKB=Q2TA10	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000033323.3\|UniProtKB=Q06AA8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000032782.3\|UniProtKB=A0A9L0T597	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845001917.1\|UniProtKB=A0A8I3MLM6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000013897.3\|UniProtKB=A0A5F8H9J8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000041165.1\|UniProtKB=A0A6I8P329	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010009086.1\|UniProtKB=A0A8V0Y1Y4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004368.3\|UniProtKB=H9G8V3	Anolis carolinensis	O
XENLA\|Gene=ube2d1.L\|UniProtKB=Q6DFK8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-954784\|UniProtKB=A0JM78	Xenopus tropicalis	O
DANRE\|ZFIN=ZDB-GENE-040426-1609\|UniProtKB=Q7SXH5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-2735\|UniProtKB=Q6PC58	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006441.1\|UniProtKB=W5MHC2	lepisosteus oculatus	O
PANTR\|Ensembl=ENSPTRG00000051267.1\|UniProtKB=A0A2I3SZE8	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037739.1\|UniProtKB=A0A2I2Z662	Gorilla gorilla gorilla	O
HUMAN\|HGNC=21647\|UniProtKB=Q9Y2X8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000045752.1\|UniProtKB=K7AUK2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000042519.1\|UniProtKB=A0A2I2ZSM0	Gorilla gorilla gorilla	LDO
BOVIN\|Ensembl=ENSBTAG00000003997.6\|UniProtKB=F1MFL6	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000019978.4\|UniProtKB=F7CFT7	Equus caballus	LDO
XENLA\|Gene=ube2d4\|UniProtKB=A5PKP9	Xenopus laevis	LDO
XENLA\|Gene=ube2d4.L\|UniProtKB=A0A8J0UQQ2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-962537\|UniProtKB=A0A803K2G6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011717.2\|UniProtKB=H2M874	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070424-86\|UniProtKB=A4QNX5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015062.1\|UniProtKB=W5ND29	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000003861.3\|UniProtKB=F6Y4V4	Ciona intestinalis	LDO
RAT\|RGD=2323338\|UniProtKB=A0A8I6GLC9	Rattus norvegicus	LDO
HORSE\|Ensembl=ENSECAG00000033999.2\|UniProtKB=A0A3Q2H7K7	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000035131.2\|UniProtKB=A0A3Q2HN60	Equus caballus	LDO
ORNAN\|Ensembl=ENSOANG00000048107.1\|UniProtKB=A0A6I8P0D4	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000028427.1\|UniProtKB=A0A3B3HWT6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-551\|UniProtKB=A9JRT4	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-030131-7384\|UniProtKB=Q6PBX6	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000021502.1\|UniProtKB=H2Y0Q2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018711.1\|UniProtKB=F6Y5B7	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_285353\|UniProtKB=C3ZGJ2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC753487\|UniProtKB=A0A7M7LSY5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587016\|UniProtKB=A0A7M7NIJ4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575905\|UniProtKB=A0A7M7NGU8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006719\|UniProtKB=Q20617	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024015\|UniProtKB=A8WND2	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00002344\|UniProtKB=P35129	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00028348\|UniProtKB=A8X150	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304562\|UniProtKB=A0A8R1Z6B0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0011217\|UniProtKB=P25867	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000145\|UniProtKB=Q7PRY1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000443\|UniProtKB=D6WA84	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_69870\|UniProtKB=E9I3T4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_120690\|UniProtKB=E9I205	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG82387\|UniProtKB=T1G4R6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG75560\|UniProtKB=T1G265	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG184920\|UniProtKB=T1FM60	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236730\|UniProtKB=A7RXR8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63134\|UniProtKB=B3S643	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_17710\|UniProtKB=A9UR38	Monosiga brevicollis	LDO
EMENI\|EnsemblGenome=ANIA_00883\|UniProtKB=Q5BEZ7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G15570\|UniProtKB=Q4WRP6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07665\|UniProtKB=Q7S9N5	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_06530\|UniProtKB=Q0UNY4	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNA02640\|UniProtKB=Q5KPI9	Cryptococcus neoformans	O
BATDJ\|Gene_ORFName=BATDEDRAFT_26696\|UniProtKB=F4P874	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_22905\|UniProtKB=F4NW55	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000002466\|UniProtKB=P15732	Saccharomyces cerevisiae	O
YEAST\|SGD=S000000286\|UniProtKB=P15731	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER173C\|UniProtKB=Q756T0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000178162\|UniProtKB=A0A1D8PU40	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D15312g\|UniProtKB=Q6C907	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02761\|UniProtKB=Q5B9M0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G06030\|UniProtKB=Q4WWI8	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02289\|UniProtKB=Q7RVS7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_11173\|UniProtKB=A7F0Q4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02749\|UniProtKB=Q0UZR5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC119.02\|UniProtKB=P46595	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04573\|UniProtKB=B6K767	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND02120\|UniProtKB=Q5KIQ6	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNF02760\|UniProtKB=Q5KF72	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00982\|UniProtKB=A0A0D1E680	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_02279\|UniProtKB=E3JXP3	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_14888\|UniProtKB=F4PEG9	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_070750\|UniProtKB=C4M5T2	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0284865\|UniProtKB=Q94490	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_48481\|UniProtKB=F0ZPB2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0290547\|UniProtKB=Q54FX4	Dictyostelium discoideum	LDO
LEIMA\|EnsemblGenome=LMJF_35_1300\|UniProtKB=Q9GNC1	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.5.1000\|UniProtKB=Q57W45	Trypanosoma brucei	LDO
GIAIC\|Gene_ORFName=GL50803_0015252\|UniProtKB=A0A644F7I8	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_191220\|UniProtKB=A2EFK5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_043860\|UniProtKB=A2E0E6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_153580\|UniProtKB=A2EPR3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_467860\|UniProtKB=A2E0M6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_257610\|UniProtKB=A2F4E2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_076890\|UniProtKB=A2D9T6	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1203900\|UniProtKB=Q8I607	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00013520001\|UniProtKB=A0D4V6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004931001\|UniProtKB=A0BJ41	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000658001\|UniProtKB=A0BUC8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039052001\|UniProtKB=A0CVS4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00038076001\|UniProtKB=A0CFR8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007512001\|UniProtKB=A0CH05	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006096001\|UniProtKB=A0C0C6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002619001\|UniProtKB=A0DQA2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012058001\|UniProtKB=A0D0D9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003257001\|UniProtKB=A0DZ21	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031081001\|UniProtKB=A0BQN5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013765001\|UniProtKB=A0D5L8	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_22432\|UniProtKB=B8C0C0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G8P2_PHYRM\|UniProtKB=H3G8P2	Phytophthora ramorum	O
PHYRM\|Gene=H3HAQ5_PHYRM\|UniProtKB=H3HAQ5	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g693700v5\|UniProtKB=A8JBJ3	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00089p00096280\|UniProtKB=W1P1R2	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_53G00060\|UniProtKB=A0A0K9NWT1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g09760\|UniProtKB=A0A804HS88	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g28520\|UniProtKB=A0A804KPP2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g12320\|UniProtKB=A0A804KIS4	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma03_g11680\|UniProtKB=A0A804IB03	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g28520\|UniProtKB=A0A804KPP2	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_031414mg\|UniProtKB=K3ZXT2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G155500\|UniProtKB=C5X897	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb309020\|UniProtKB=B4FCQ9	Zea mays	O
SETIT\|EnsemblGenome=SETIT_019237mg\|UniProtKB=K3YY87	Setaria italica	LDO
MAIZE\|EnsemblGenome=Zm00001eb097550\|UniProtKB=B6U4K0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0293400\|UniProtKB=Q69JN7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g27430v3\|UniProtKB=I1IP59	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0471520\|UniProtKB=A0A8I6XP97	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G181400\|UniProtKB=A0A3B6MQQ7	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G174300\|UniProtKB=A0A3B6LL01	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G177100\|UniProtKB=A0A3B6KHB9	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_025412\|UniProtKB=A0A1U7Z3R7	Nelumbo nucifera	O
NELNU\|Gene=LOC104609421\|UniProtKB=A0A1U8B034	Nelumbo nucifera	O
PRUPE\|EnsemblGenome=PRUPE_1G008300\|UniProtKB=A0A251QRV4	Prunus persica	O
NELNU\|Gene=LOC104594343\|UniProtKB=A0A1U7ZWL5	Nelumbo nucifera	LDO
TOBAC\|Gene=LOC107788577\|UniProtKB=A0A1S3ZMY8	Nicotiana tabacum	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E04235\|UniProtKB=A0A059CB82	Eucalyptus grandis	LDO
THECC\|EnsemblGenome=TCM_034533\|UniProtKB=A0A061FFI9	Theobroma cacao	LDO
POPTR\|Gene_ORFName=POPTR_017G055300\|UniProtKB=A0A3N7G574	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_1019510\|UniProtKB=B9RWH5	Ricinus communis	LDO
PRUPE\|EnsemblGenome=PRUPE_4G150600\|UniProtKB=M5X5F5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_187468\|UniProtKB=D8SFW4	Selaginella moellendorffii	LDO
MARPO\|EnsemblGenome=MARPO_0140s0024\|UniProtKB=A0A2R6W6L2	Marchantia polymorpha	LDO