PANTHER Gene Information   
Gene Symbol(s): UBE2D1
Organism: Sus scrofa
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Gene Name: UB2D1
Gene ID: ENSSSCG00000033323.3
Protein ID: Q06AA8
Persistent Id: PTN004660793
Alternate Ids:
NM_001078674(refSeq) Q06AA8(Synonym)
DQIR01148019(EMBL) HDB03496(EMBL-CDS)
ENSSSCP00000060970(Ensembl_PRO) 780419(GeneID)
ENSSSCG00000033323(Ensembl) 118403844(GI)
ENSSSCT00000080543(Ensembl_TRS) Q06AA8_PIG(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily: UBIQUITIN-CONJUGATING ENZYME E2 D1 (PTHR24068:SF36)  
PANTHER GO-slim Molecular Function: ubiquitin conjugating enzyme activity
ubiquitin protein ligase binding
PANTHER GO-slim Biological Process: protein K48-linked ubiquitination
ubiquitin-dependent protein catabolic process
PANTHER GO-slim Cellular Component: nucleus
ubiquitin ligase complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: Ubiquitin proteasome pathway
   Ubiquitin-conjugating enzyme E2
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, ubiquitin protein ligase activity, ubiquitin conjugating enzyme activity
GO BP Complete: proteasome-mediated ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, negative regulation of TORC1 signaling, positive regulation of protein ubiquitination, ubiquitin-dependent protein catabolic process
GO CC Complete: nucleus, cytoplasm, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Regulation of TNFR1 signaling, Signal Transduction, TNF signaling, Synthesis of active ubiquitin: roles of E1 and E2 enzymes, Peroxisomal protein import, Metabolism of proteins, Post-translational protein modification, Gene expression (Transcription), Senescence-Associated Secretory Phenotype (SASP), DNA Replication Pre-Initiation, S Phase, E3 ubiquitin ligases ubiquitinate target proteins, APC/C:Cdc20 mediated degradation of Cyclin B, Cellular response to hypoxia, Cellular Senescence, IKK complex recruitment mediated by RIP1, Innate Immune System, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha, Autodegradation of Cdh1 by Cdh1:APC/C, Protein ubiquitination, Assembly of the pre-replicative complex, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Signaling by TGF-beta Receptor Complex, Downregulation of SMAD2/3:SMAD4 transcriptional activity, Synthesis of DNA, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, Death Receptor Signaling, Cell Cycle, Mitotic, Cellular responses to stress, Cell Cycle, Phosphorylation of the APC/C, Antigen processing: Ubiquitination & Proteasome degradation, Deubiquitination, Class I MHC mediated antigen processing & presentation, Mitotic Metaphase and Anaphase, APC/C:Cdc20 mediated degradation of Securin, Toll Like Receptor 4 (TLR4) Cascade, Protein localization, Regulation of mitotic cell cycle, DNA Replication, Signaling by BMP, APC/C:Cdc20 mediated degradation of mitotic proteins, Adaptive Immune System, Regulation of APC/C activators between G1/S and early anaphase, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase, APC-Cdc20 mediated degradation of Nek2A, MyD88-independent TLR4 cascade , Cell Cycle Checkpoints, APC/C-mediated degradation of cell cycle proteins, Neddylation, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, TRIF(TICAM1)-mediated TLR4 signaling , RNA Polymerase II Transcription, Ovarian tumor domain proteases, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, Mitotic Spindle Checkpoint, Mitotic Anaphase, CDK-mediated phosphorylation and removal of Cdc6, Generic Transcription Pathway, Immune System, Signaling by TGFB family members, M Phase, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Toll-like Receptor Cascades, Inactivation of APC/C via direct inhibition of the APC/C complex, Cellular responses to stimuli, Separation of Sister Chromatids, Switching of origins to a post-replicative state

Orthologs