PANTHER Gene Information

Gene Symbol(s):

Organism:

lepisosteus oculatus

View Gene in Tree

Tree

Gene Name:

Phosphatidylinositol 3-kinase regulatory subunit alpha

Gene ID:

ENSLOCG00000010510.1

Protein ID:

W5MWX5

Persistent Id:

PTN002562661

Alternate Ids:

W5MWX5_LEPOC(UniProtKB-ID)	ENSLOCG00000010510(Ensembl)
AHAT01013338(EMBL)	ENSLOCP00000012884(Ensembl_PRO)
ENSLOCT00000012910(Ensembl_TRS)	W5MWX5(Synonym)
Show All

PANTHER Classification

PANTHER Family:	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)
PANTHER Subfamily:	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA (PTHR10155:SF3)
PANTHER GO-slim Molecular Function:	kinase regulator activity
PANTHER GO-slim Biological Process:	phosphatidylinositol phosphate biosynthetic process insulin receptor signaling pathway
PANTHER GO-slim Cellular Component:	phosphatidylinositol 3-kinase complex
PANTHER protein class:	kinase modulator

Pathway Categories:

VEGF signaling pathway

Phosphatidylinositol 3-kinase

PI3 kinase pathway

p85

T cell activation

Phosphatidylinositol 3-kinase

Hypoxia response via HIF activation

Phosphatidylinositol 3-kinase

Insulin/IGF pathway-protein kinase B signaling cascade

Phosphatidylinositol 3-kinase

Angiogenesis

Phosphatidylinositol 3-kinase

Integrin signalling pathway

Phosphatidylinositol 3-kinase

Axon guidance mediated by netrin

Phosphatidylinositol 3-kinase

Endothelin signaling pathway

Phosphatidylinositol 3-kinase

PDGF signaling pathway

Phosphatidylinositol 3-kinase

p53 pathway feedback loops 2

Phosphatidylinositol 3-kinase

Gonadotropin-releasing hormone receptor pathway

PI3K

CCKR signaling map

p85

p53 pathway

Phosphatidylinositol 3-kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	1-phosphatidylinositol-3-kinase regulator activity
GO BP Complete:	signal transduction, insulin receptor signaling pathway
GO CC Complete:	phosphatidylinositol 3-kinase complex, class IA

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8979\|UniProtKB=P27986	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016940.5\|UniProtKB=A0A2I3SIY1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004248.3\|UniProtKB=A0A2I2ZTD7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011532.4\|UniProtKB=F7BZL6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97583\|UniProtKB=P26450	Mus musculus	LDO
RAT\|RGD=3329\|UniProtKB=Q63787	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010989\|UniProtKB=P23727	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016958.6\|UniProtKB=F1SKR9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019837.3\|UniProtKB=F7CEQ6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011030.6\|UniProtKB=M3WED2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011717.1\|UniProtKB=A0A8I3N971	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019685.4\|UniProtKB=F6TD14	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045580.1\|UniProtKB=A0A6I8PD71	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011922.1\|UniProtKB=A0A3Q3ACS4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016290.3\|UniProtKB=G1KSH1	Anolis carolinensis	LDO
XENLA\|Gene=pik3r1-a\|UniProtKB=Q8UUU2	Xenopus laevis	O
XENLA\|Gene=pik3r1.S\|UniProtKB=A0A8J1LM99	Xenopus laevis	O
XENLA\|Gene=pik3r1.L\|UniProtKB=Q6GQ43	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6067221\|UniProtKB=F6Z0J4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017457.2\|UniProtKB=H2MSU3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002670.2\|UniProtKB=H2LBP9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-1280\|UniProtKB=B0S6V7	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000023616.1\|UniProtKB=F7BLX7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118432571\|UniProtKB=A0A9J7MFS2	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00000001\|UniProtKB=G5EDP9	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00032086\|UniProtKB=A8XBV2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00117228\|UniProtKB=A0A2A6BTE0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0020622\|UniProtKB=Q7KTZ2	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005583\|UniProtKB=A0A1S4GQF6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC030884\|UniProtKB=A0A139WP68	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_43714\|UniProtKB=E9G0D1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_111818\|UniProtKB=E9HA70	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011707\|UniProtKB=B7Q548	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG76166\|UniProtKB=T1G2G0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g84479\|UniProtKB=A7RK55	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_33139\|UniProtKB=A9V3X4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33736\|UniProtKB=A9V765	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10565\|UniProtKB=A9V6R6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_24251\|UniProtKB=A9UVV0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_9122\|UniProtKB=A9V255	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33646\|UniProtKB=A9V6S8	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10537\|UniProtKB=A9V6N4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_12142\|UniProtKB=A9VBC5	Monosiga brevicollis	O
PHYRM\|Gene=H3GME9_PHYRM\|UniProtKB=H3GME9	Phytophthora ramorum	O