PANTHER Gene Information   
Gene Symbol(s): PIK3R1
Organism: Ornithorhynchus anatinus
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Gene Name: Phosphoinositide-3-kinase regulatory subunit 1
Gene ID: ENSOANG00000045580.1
Protein ID: A0A6I8PD71
Persistent Id: PTN008938818
Alternate Ids:
A0A6I8PD71(Synonym) A0A6I8PD71_ORNAN(UniProtKB-ID)
ENSOANG00000045580(Ensembl) ENSOANT00000047306(Ensembl_TRS)
ENSOANP00000052559(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT (PTHR10155)
PANTHER Subfamily: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA (PTHR10155:SF3)  
PANTHER GO-slim Molecular Function: kinase regulator activity
PANTHER GO-slim Biological Process: phosphatidylinositol phosphate biosynthetic process
insulin receptor signaling pathway
PANTHER GO-slim Cellular Component: phosphatidylinositol 3-kinase complex
PANTHER protein class: kinase modulator
Pathway Categories: VEGF signaling pathway
   Phosphatidylinositol 3-kinase
PI3 kinase pathway
   p85
T cell activation
   Phosphatidylinositol 3-kinase
Hypoxia response via HIF activation
   Phosphatidylinositol 3-kinase
Insulin/IGF pathway-protein kinase B signaling cascade
   Phosphatidylinositol 3-kinase
Angiogenesis
   Phosphatidylinositol 3-kinase
Integrin signalling pathway
   Phosphatidylinositol 3-kinase
Axon guidance mediated by netrin
   Phosphatidylinositol 3-kinase
Endothelin signaling pathway
   Phosphatidylinositol 3-kinase
PDGF signaling pathway
   Phosphatidylinositol 3-kinase
p53 pathway feedback loops 2
   Phosphatidylinositol 3-kinase
Gonadotropin-releasing hormone receptor pathway
   PI3K
CCKR signaling map
   p85
p53 pathway
   Phosphatidylinositol 3-kinase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: phosphotyrosine residue binding, insulin binding, protein phosphatase binding, phosphatidylinositol 3-kinase regulator activity, ErbB-3 class receptor binding, insulin receptor binding, neurotrophin TRKA receptor binding, 1-phosphatidylinositol-3-kinase regulator activity, insulin-like growth factor receptor binding
GO BP Complete: growth hormone receptor signaling pathway, positive regulation of protein import into nucleus, signal transduction, insulin receptor signaling pathway, positive regulation of RNA splicing, regulation of toll-like receptor 4 signaling pathway, insulin-like growth factor receptor signaling pathway, natural killer cell mediated cytotoxicity, positive regulation of endoplasmic reticulum unfolded protein response, positive regulation of transcription by RNA polymerase II, cellular response to insulin stimulus, positive regulation of smooth muscle cell proliferation, phosphatidylinositol 3-kinase/protein kinase B signal transduction, cytokine-mediated signaling pathway, negative regulation of apoptotic process, protein stabilization, response to endoplasmic reticulum stress, interleukin-18-mediated signaling pathway
GO CC Complete: phosphatidylinositol 3-kinase complex, class IA, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs